Ptprr (protein tyrosine phosphatase receptor type R) - Rat Genome Database

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Gene: Ptprr (protein tyrosine phosphatase receptor type R) Ictidomys tridecemlineatus
Analyze
Symbol: Ptprr
Name: protein tyrosine phosphatase receptor type R (Ensembl:receptor-type tyrosine-protein phosphatase R)
RGD ID: 12635468
Description: ENCODES a protein that exhibits protein kinase binding (inferred); protein tyrosine phosphatase activity (inferred); INVOLVED IN nervous system development (ortholog); neuron differentiation (ortholog); regulation of homophilic cell adhesion (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cell junction (inferred); cytosol (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC101964395; receptor-type tyrosine-protein phosphatase R; receptor-type tyrosine-protein phosphatase R, transcript variant X1; receptor-type tyrosine-protein phosphatase R, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494545,732,053 - 45,841,891 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365458,268,218 - 8,377,169 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365458,268,227 - 8,377,427 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ptprr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494545,732,053 - 45,841,891 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365458,268,218 - 8,377,169 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365458,268,227 - 8,377,427 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381270,638,073 - 70,920,738 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1270,638,073 - 70,920,738 (-)EnsemblGRCh38hg38GRCh38
GRCh371271,031,853 - 71,314,518 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361269,318,129 - 69,600,853 (-)NCBINCBI36Build 36hg18NCBI36
Build 341269,318,128 - 69,434,632NCBI
Celera1270,695,535 - 70,977,822 (-)NCBICelera
Cytogenetic Map12q15NCBI
HuRef1268,081,248 - 68,364,028 (-)NCBIHuRef
CHM1_11271,001,121 - 71,283,977 (-)NCBICHM1_1
T2T-CHM13v2.01270,617,477 - 70,900,236 (-)NCBIT2T-CHM13v2.0
Ptprr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910115,854,093 - 116,110,837 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10115,854,118 - 116,110,837 (+)EnsemblGRCm39 Ensembl
GRCm3810116,018,188 - 116,274,932 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10116,018,213 - 116,274,932 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710115,455,419 - 115,711,985 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610115,422,509 - 115,679,039 (+)NCBIMGSCv36mm8
Celera10117,959,423 - 118,215,461 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1064.01NCBI
Ptprr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8753,548,611 - 53,815,632 (+)NCBIGRCr8
mRatBN7.2751,662,595 - 51,929,605 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl751,662,595 - 51,929,603 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx753,569,319 - 53,836,323 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0755,772,411 - 56,039,410 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0755,550,399 - 55,817,402 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0759,039,717 - 59,325,925 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl759,039,720 - 59,325,947 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0759,041,711 - 59,084,462 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0759,207,155 - 59,335,376 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4755,324,246 - 55,612,945 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1755,344,975 - 55,633,672 (+)NCBI
Celera748,446,749 - 48,710,763 (+)NCBICelera
Cytogenetic Map7q22NCBI
Ptprr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540510,767,507 - 11,026,914 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540510,767,548 - 11,133,695 (-)NCBIChiLan1.0ChiLan1.0
PTPRR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21078,653,652 - 78,936,078 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11278,650,051 - 78,932,477 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01268,148,200 - 68,430,618 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11270,915,951 - 71,197,146 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1270,915,951 - 71,196,732 (-)Ensemblpanpan1.1panPan2
PTPRR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11012,385,121 - 12,618,438 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1012,385,107 - 12,594,004 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1012,324,091 - 12,557,686 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01012,517,368 - 12,751,240 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1012,517,368 - 12,751,216 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11012,382,959 - 12,616,783 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01012,630,054 - 12,863,956 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01012,754,267 - 12,988,172 (-)NCBIUU_Cfam_GSD_1.0
PTPRR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl534,794,977 - 35,047,818 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1534,794,970 - 35,048,550 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2537,346,846 - 37,511,950 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11166,222,495 - 66,496,247 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1166,223,605 - 66,353,700 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037179,171,480 - 179,454,986 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptprr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475026,906,871 - 27,188,249 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475026,907,292 - 27,188,129 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000013136   ⟹   ENSSTOP00000011775
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365458,268,218 - 8,377,169 (-)Ensembl
RefSeq Acc Id: XM_005328751   ⟹   XP_005328808
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494545,732,053 - 45,841,891 (+)NCBI
SpeTri2.0NW_0049365458,268,227 - 8,377,427 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040280318   ⟹   XP_040136252
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494545,740,572 - 45,841,891 (+)NCBI
RefSeq Acc Id: XM_040280319   ⟹   XP_040136253
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494545,733,081 - 45,841,891 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005328808 (Get FASTA)   NCBI Sequence Viewer  
  XP_040136252 (Get FASTA)   NCBI Sequence Viewer  
  XP_040136253 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000011775.3
GenBank Protein KAG3291375 (Get FASTA)   NCBI Sequence Viewer  
  KAG3291376 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005328808   ⟸   XM_005328751
- Peptide Label: isoform X1
- UniProtKB: I3MKG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040136253   ⟸   XM_040280319
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040136252   ⟸   XM_040280318
- Peptide Label: isoform X1
- UniProtKB: I3MKG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000011775   ⟸   ENSSTOT00000013136
Protein Domains
Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000013134 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000013136.3 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/TrEMBL
InterPro Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTPase_domain UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_KIM-con UniProtKB/TrEMBL
  Tyr_Pase_rcpt_R/non-rcpt_5 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
NCBI Gene Ptprr ENTREZGENE
PANTHER PTHR46198 UniProtKB/TrEMBL
  RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE R UniProtKB/TrEMBL
Pfam Y_phosphatase UniProtKB/TrEMBL
PIRSF PTPRR UniProtKB/TrEMBL
PRINTS KIMPTPASE UniProtKB/TrEMBL
  PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/TrEMBL
UniProt I3MKG3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-26 Ptprr  protein tyrosine phosphatase receptor type R  LOC101964395  receptor-type tyrosine-protein phosphatase R  Symbol and/or name change 5135510 APPROVED
2017-07-13 LOC101964395  receptor-type tyrosine-protein phosphatase R  Ptprr  protein tyrosine phosphatase, receptor type R  Symbol and/or name change 5135510 APPROVED