Rictor (RPTOR independent companion of MTOR complex 2) - Rat Genome Database

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Gene: Rictor (RPTOR independent companion of MTOR complex 2) Ictidomys tridecemlineatus
Analyze
Symbol: Rictor
Name: RPTOR independent companion of MTOR complex 2
RGD ID: 12633115
Description: ENCODES a protein that exhibits molecular adaptor activity (inferred); protein kinase binding (inferred); protein serine/threonine kinase activator activity (inferred); INVOLVED IN positive regulation of actin filament polymerization (ortholog); positive regulation of endothelial cell proliferation (ortholog); positive regulation of peptidyl-tyrosine phosphorylation (ortholog); PARTICIPATES IN mTOR signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); colon cancer (ortholog); colorectal adenocarcinoma (ortholog); FOUND IN TORC2 complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rapamycin-insensitive companion of mTOR
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213228,057,440 - 228,173,553 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365183,198,337 - 3,310,000 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365183,198,312 - 3,314,393 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
TORC2 complex  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Rictor
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213228,057,440 - 228,173,553 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365183,198,337 - 3,310,000 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365183,198,312 - 3,314,393 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RICTOR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38538,937,920 - 39,074,399 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl538,937,920 - 39,074,402 (-)EnsemblGRCh38hg38GRCh38
GRCh37538,938,022 - 39,074,501 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36538,973,779 - 39,110,260 (-)NCBINCBI36Build 36hg18NCBI36
Celera538,824,519 - 38,961,093 (-)NCBICelera
Cytogenetic Map5p13.1NCBI
HuRef538,889,559 - 39,026,140 (-)NCBIHuRef
CHM1_1538,939,974 - 39,076,492 (-)NCBICHM1_1
T2T-CHM13v2.0539,187,325 - 39,323,906 (-)NCBIT2T-CHM13v2.0
Rictor
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39156,737,827 - 6,829,882 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl156,737,860 - 6,829,882 (+)EnsemblGRCm39 Ensembl
GRCm38156,708,349 - 6,800,401 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl156,708,379 - 6,800,401 (+)EnsemblGRCm38mm10GRCm38
MGSCv37156,658,381 - 6,750,401 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36156,655,598 - 6,747,602 (+)NCBIMGSCv36mm8
Celera156,556,757 - 6,648,820 (+)NCBICelera
Cytogenetic Map15A1NCBI
cM Map153.25NCBI
Rictor
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8257,539,279 - 57,631,291 (+)NCBIGRCr8
mRatBN7.2255,811,877 - 55,903,893 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl255,811,322 - 55,901,426 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0256,013,898 - 56,105,818 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl256,052,643 - 56,101,803 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0275,754,848 - 75,846,705 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4255,982,784 - 56,071,528 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1255,911,016 - 55,999,761 (+)NCBI
Celera251,432,223 - 51,524,001 (+)NCBICelera
Cytogenetic Map2q16NCBI
Rictor
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542623,468,112 - 23,582,587 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542623,468,112 - 23,582,587 (-)NCBIChiLan1.0ChiLan1.0
RICTOR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2471,261,938 - 71,398,082 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1569,415,572 - 69,551,716 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0571,299,215 - 71,435,290 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1576,390,408 - 76,474,207 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl576,389,130 - 76,469,830 (+)Ensemblpanpan1.1panPan2
RICTOR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1469,903,393 - 70,013,168 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl469,936,379 - 70,010,566 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha469,572,398 - 69,689,560 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0470,411,989 - 70,529,395 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl470,412,019 - 70,529,395 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1470,160,959 - 70,278,302 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0470,273,578 - 70,390,878 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0470,812,437 - 70,929,811 (+)NCBIUU_Cfam_GSD_1.0
RICTOR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1624,109,939 - 24,311,132 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11624,109,934 - 24,250,019 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21625,357,044 - 25,498,055 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RICTOR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1437,758,531 - 37,885,323 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl437,762,901 - 37,873,766 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607128,126,791 - 28,254,601 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rictor
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475915,837,064 - 15,968,894 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475915,837,027 - 15,973,248 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000005750   ⟹   ENSSTOP00000005142
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365183,198,337 - 3,310,000 (+)Ensembl
RefSeq Acc Id: XM_040273380   ⟹   XP_040129314
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213228,057,440 - 228,173,553 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040129314 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000005142.3
GenBank Protein KAG3266836 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040129314   ⟸   XM_040273380
- UniProtKB: I3M6M2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000005142   ⟸   ENSSTOT00000005750
Protein Domains
Rapamycin-insensitive companion of mTOR   Rapamycin-insensitive companion of mTOR middle   Rapamycin-insensitive companion of mTOR N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000005716 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000005750.3 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  Pianissimo_fam UniProtKB/TrEMBL
  Pianissimo_N UniProtKB/TrEMBL
  Rictor_IV UniProtKB/TrEMBL
  RICTOR_M UniProtKB/TrEMBL
  RICTOR_phospho UniProtKB/TrEMBL
  RICTOR_V UniProtKB/TrEMBL
NCBI Gene Rictor ENTREZGENE
PANTHER PTHR13298 UniProtKB/TrEMBL
  RAPAMYCIN-INSENSITIVE COMPANION OF MTOR UniProtKB/TrEMBL
Pfam RasGEF_N_2 UniProtKB/TrEMBL
  RICTOR_M UniProtKB/TrEMBL
  RICTOR_N UniProtKB/TrEMBL
  RICTOR_phospho UniProtKB/TrEMBL
  RICTOR_V UniProtKB/TrEMBL
SMART RasGEF_N_2 UniProtKB/TrEMBL
  RICTOR_M UniProtKB/TrEMBL
  RICTOR_N UniProtKB/TrEMBL
  RICTOR_phospho UniProtKB/TrEMBL
  RICTOR_V UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt I3M6M2 ENTREZGENE, UniProtKB/TrEMBL