Nbn (nibrin) - Rat Genome Database

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Gene: Nbn (nibrin) Ictidomys tridecemlineatus
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Symbol: Nbn
Name: nibrin
RGD ID: 12632895
Description: ENCODES a protein that exhibits damaged DNA binding (ortholog); DNA-binding transcription factor binding (ortholog); protein N-terminus binding (ortholog); INVOLVED IN blastocyst growth (ortholog); cell population proliferation (ortholog); DNA damage checkpoint signaling (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; homologous recombination pathway of double-strand break repair; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); Alzheimer's disease (ortholog); aplastic anemia (ortholog); FOUND IN chromosome, telomeric region (ortholog); Mre11 complex (ortholog); nuclear inclusion body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530343,980,776 - 44,018,864 (+)NCBI
SpeTri2.0NW_0049365443,773,828 - 3,812,673 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Nbn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530343,980,776 - 44,018,864 (+)NCBI
SpeTri2.0NW_0049365443,773,828 - 3,812,673 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NBN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl889,933,331 - 90,003,228 (-)EnsemblGRCh38hg38GRCh38
GRCh38889,933,331 - 89,984,698 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37890,945,559 - 90,996,895 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36891,014,740 - 91,066,075 (-)NCBINCBI36hg18NCBI36
Build 34891,014,888 - 91,066,072NCBI
Celera887,140,375 - 87,191,710 (-)NCBI
Cytogenetic Map8q21.3NCBI
HuRef886,155,741 - 86,207,078 (-)NCBIHuRef
CHM1_1890,986,489 - 91,037,825 (-)NCBICHM1_1
Nbn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39415,955,388 - 15,992,589 (+)NCBIGRCm39mm39
GRCm39 Ensembl415,957,925 - 15,992,589 (+)Ensembl
GRCm38415,957,587 - 15,992,589 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl415,957,925 - 15,992,589 (+)EnsemblGRCm38mm10GRCm38
MGSCv37415,885,114 - 15,919,736 (+)NCBIGRCm37mm9NCBIm37
MGSCv36415,885,115 - 15,919,736 (+)NCBImm8
Celera415,761,229 - 15,795,887 (+)NCBICelera
Cytogenetic Map4A2NCBI
Nbn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2529,459,574 - 29,494,152 (+)NCBI
Rnor_6.0 Ensembl529,622,281 - 29,656,864 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0529,622,347 - 29,656,877 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0534,300,932 - 34,335,393 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4530,541,610 - 30,576,168 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1530,541,609 - 30,576,168 (+)NCBI
Celera528,665,088 - 28,699,404 (+)NCBICelera
Cytogenetic Map5q13NCBI
Nbn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554176,839,312 - 6,880,133 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554176,840,916 - 6,880,479 (-)NCBIChiLan1.0ChiLan1.0
NBN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1888,575,198 - 88,626,200 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl888,575,198 - 88,626,307 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0886,622,797 - 86,674,202 (-)NCBIMhudiblu_PPA_v0panPan3
NBN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12935,416,093 - 35,477,569 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2935,416,093 - 35,477,563 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2935,567,773 - 35,628,935 (-)NCBI
ROS_Cfam_1.02935,612,774 - 35,674,851 (-)NCBI
UMICH_Zoey_3.12935,604,159 - 35,665,432 (-)NCBI
UNSW_CanFamBas_1.02935,624,597 - 35,685,889 (-)NCBI
UU_Cfam_GSD_1.02936,059,084 - 36,120,657 (-)NCBI
NBN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl446,787,659 - 46,903,999 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1446,787,664 - 46,854,331 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2451,264,106 - 51,288,533 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NBN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1885,017,807 - 85,069,219 (-)NCBI
ChlSab1.1 Ensembl885,015,752 - 85,069,028 (-)Ensembl
Vero_WHO_p1.0NW_02366603955,810,092 - 55,861,864 (+)NCBI
Nbn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247442,013,936 - 2,061,726 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005328678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005328678   ⟹   XP_005328735
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530343,980,776 - 44,018,864 (+)NCBI
SpeTri2.0NW_0049365443,773,828 - 3,812,673 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005328735 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3273923 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005328735   ⟸   XM_005328678
- Sequence:
Protein Domains
FHA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015180 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000013605 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015184 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10190 UniProtKB/TrEMBL
  3.40.50.10980 UniProtKB/TrEMBL
InterPro BRCT_dom_sf UniProtKB/TrEMBL
  DNA-repair_Nbs1_C UniProtKB/TrEMBL
  FHA_dom UniProtKB/TrEMBL
  Nibrin-rel UniProtKB/TrEMBL
  Nibrin_BRCT2 UniProtKB/TrEMBL
  Nibrin_BRCT2_sf UniProtKB/TrEMBL
  Nibrin_met UniProtKB/TrEMBL
  SMAD_FHA_dom_sf UniProtKB/TrEMBL
NCBI Gene Nbn ENTREZGENE
PANTHER PTHR12162 UniProtKB/TrEMBL
Pfam FHA UniProtKB/TrEMBL
  Nbs1_C UniProtKB/TrEMBL
  NIBRIN_BRCT_II UniProtKB/TrEMBL
PIRSF Nibrin_animal UniProtKB/TrEMBL
PROSITE FHA_DOMAIN UniProtKB/TrEMBL
SMART FHA UniProtKB/TrEMBL
  Nbs1_C UniProtKB/TrEMBL
Superfamily-SCOP SSF49879 UniProtKB/TrEMBL
  SSF52113 UniProtKB/TrEMBL
UniProt I3MPB1_ICTTR UniProtKB/TrEMBL