Trim21 (tripartite motif containing 21) - Rat Genome Database

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Gene: Trim21 (tripartite motif containing 21) Ictidomys tridecemlineatus
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Symbol: Trim21
Name: tripartite motif containing 21
RGD ID: 12631202
Description: ENCODES a protein that exhibits identical protein binding (ortholog); transcription coactivator activity (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN innate immune response (ortholog); negative regulation of innate immune response (ortholog); negative regulation of NF-kappaB transcription factor activity (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: E3 ubiquitin-protein ligase TRIM21
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494759,090,839 - 59,097,841 (+)NCBI
SpeTri2.0NW_004936498690,481 - 697,305 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
Trim21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494759,090,839 - 59,097,841 (+)NCBI
SpeTri2.0NW_004936498690,481 - 697,305 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl114,384,897 - 4,393,702 (-)EnsemblGRCh38hg38GRCh38
GRCh38114,384,897 - 4,393,702 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37114,406,127 - 4,414,932 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36114,362,703 - 4,371,502 (-)NCBINCBI36hg18NCBI36
Build 34114,362,702 - 4,371,502NCBI
Celera114,530,327 - 4,539,126 (-)NCBI
Cytogenetic Map11p15.4NCBI
HuRef114,064,388 - 4,073,231 (-)NCBIHuRef
CHM1_1114,406,038 - 4,414,832 (-)NCBICHM1_1
Trim21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397102,207,127 - 102,214,689 (-)NCBIGRCm39mm39
GRCm39 Ensembl7102,207,128 - 102,214,693 (-)Ensembl
GRCm387102,557,920 - 102,565,482 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7102,557,921 - 102,565,486 (-)EnsemblGRCm38mm10GRCm38
MGSCv377109,706,436 - 109,713,983 (-)NCBIGRCm37mm9NCBIm37
MGSCv367102,431,745 - 102,439,243 (-)NCBImm8
Celera7102,922,872 - 102,930,525 (-)NCBICelera
Cytogenetic Map7E3NCBI
Trim21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21156,964,896 - 156,987,504 (-)NCBI
Rnor_6.0 Ensembl1167,686,173 - 167,708,714 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01167,686,148 - 167,708,735 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01173,871,557 - 173,894,155 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41160,175,882 - 160,187,661 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11160,254,898 - 160,276,114 (-)NCBI
Celera1155,032,978 - 155,043,976 (-)NCBICelera
Cytogenetic Map1q32NCBI
Trim21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541420,070,359 - 20,077,595 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541420,066,109 - 20,077,331 (-)NCBIChiLan1.0ChiLan1.0
TRIM21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1114,254,152 - 4,262,981 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl114,254,152 - 4,262,981 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0114,588,083 - 4,596,942 (-)NCBIMhudiblu_PPA_v0panPan3
TRIM21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12126,775,227 - 26,783,180 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2126,775,672 - 26,783,725 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2126,545,768 - 26,553,727 (-)NCBI
ROS_Cfam_1.02127,008,568 - 27,016,531 (-)NCBI
UMICH_Zoey_3.12126,775,451 - 26,783,414 (-)NCBI
UNSW_CanFamBas_1.02127,014,746 - 27,022,703 (-)NCBI
UU_Cfam_GSD_1.02126,901,794 - 26,909,757 (-)NCBI
TRIM21
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl95,782,200 - 5,791,577 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.195,782,133 - 5,790,628 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.296,536,099 - 6,544,261 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1162,451,808 - 62,460,658 (+)NCBI
ChlSab1.1 Ensembl162,451,830 - 62,460,659 (+)Ensembl
Vero_WHO_p1.0NW_02366604363,449,436 - 63,458,306 (-)NCBI
Trim21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248175,643,788 - 5,651,514 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005323314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005323314   ⟹   XP_005323371
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494759,090,839 - 59,097,841 (+)NCBI
SpeTri2.0NW_004936498690,481 - 697,305 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005323371 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3286009 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005323371   ⟸   XM_005323314
- UniProtKB: I3M569 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
B box-type   B30.2/SPRY   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004965 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000004448 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004960 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
  Ubox_domain UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
  Znf_B-box_chordata UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene Trim21 ENTREZGENE
Pfam PRY UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/TrEMBL
PRINTS BBOXZNFINGER UniProtKB/TrEMBL
  BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART BBOX UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
  Ubox UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/TrEMBL
UniProt I3M569 ENTREZGENE, UniProtKB/TrEMBL