Aldh1a3 (aldehyde dehydrogenase 1 family member A3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Aldh1a3 (aldehyde dehydrogenase 1 family member A3) Ictidomys tridecemlineatus
Analyze
Symbol: Aldh1a3
Name: aldehyde dehydrogenase 1 family member A3
RGD ID: 12631018
Description: ENCODES a protein that exhibits aldehyde dehydrogenase [NAD(P)+] activity (ortholog); INVOLVED IN apoptotic process (ortholog); embryonic camera-type eye development (ortholog); embryonic eye morphogenesis (ortholog); PARTICIPATES IN retinoic acid metabolic pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 15q26-qter deletion syndrome (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: aldehyde dehydrogenase family 1 member A3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640143,367,150 - 143,403,705 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364832,930,789 - 2,967,346 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364832,930,781 - 2,967,309 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Aldh1a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640143,367,150 - 143,403,705 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364832,930,789 - 2,967,346 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364832,930,781 - 2,967,309 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALDH1A3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3815100,879,831 - 100,916,626 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl15100,877,714 - 100,916,626 (+)EnsemblGRCh38hg38GRCh38
GRCh3715101,420,036 - 101,456,831 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361599,237,532 - 99,274,354 (+)NCBINCBI36Build 36hg18NCBI36
Build 341599,237,583 - 99,274,352NCBI
Celera1577,832,935 - 77,870,170 (+)NCBICelera
Cytogenetic Map15q26.3NCBI
HuRef1577,542,416 - 77,578,726 (+)NCBIHuRef
CHM1_115101,260,984 - 101,297,814 (+)NCBICHM1_1
T2T-CHM13v2.01598,634,889 - 98,671,163 (+)NCBIT2T-CHM13v2.0
Aldh1a3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39766,040,640 - 66,077,225 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl766,040,638 - 66,077,265 (-)EnsemblGRCm39 Ensembl
GRCm38766,390,892 - 66,427,477 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl766,390,890 - 66,427,517 (-)EnsemblGRCm38mm10GRCm38
MGSCv37773,535,778 - 73,572,363 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36766,269,842 - 66,313,378 (-)NCBIMGSCv36mm8
Celera763,845,586 - 63,882,073 (-)NCBICelera
Cytogenetic Map7CNCBI
cM Map735.73NCBI
Aldh1a3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81129,392,516 - 129,436,552 (-)NCBIGRCr8
mRatBN7.21119,982,272 - 120,017,416 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1119,982,277 - 120,017,436 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1127,975,926 - 128,009,224 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01135,147,379 - 135,180,677 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01127,957,727 - 127,991,000 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01127,302,920 - 127,337,828 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1127,301,128 - 127,337,882 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01128,382,914 - 128,415,160 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41120,847,746 - 120,881,883 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11120,926,088 - 120,960,226 (-)NCBI
Celera1112,188,129 - 112,221,404 (-)NCBICelera
Cytogenetic Map1q22NCBI
Aldh1a3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541627,823,611 - 27,858,173 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541627,823,611 - 27,858,112 (+)NCBIChiLan1.0ChiLan1.0
ALDH1A3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21690,469,977 - 90,506,962 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11594,170,122 - 94,207,128 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01579,603,893 - 79,640,866 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11598,891,776 - 98,928,286 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1598,891,770 - 98,928,396 (+)Ensemblpanpan1.1panPan2
ALDH1A3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1340,130,904 - 40,168,686 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl340,132,726 - 40,168,664 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha342,820,112 - 42,857,782 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0340,522,454 - 40,560,130 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl340,522,340 - 40,560,113 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1340,054,895 - 40,092,579 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0340,292,280 - 40,329,945 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0340,494,117 - 40,531,822 (-)NCBIUU_Cfam_GSD_1.0
ALDH1A3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1139,451,049 - 139,491,511 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11139,451,080 - 139,491,514 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21155,732,334 - 155,751,055 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ALDH1A3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12919,347,101 - 19,383,600 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605927,159,145 - 27,196,034 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aldh1a3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247683,851,257 - 3,885,609 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247683,851,361 - 3,885,609 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005320083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010003700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000008962   ⟹   ENSSTOP00000008032
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364832,932,765 - 2,967,215 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000039150   ⟹   ENSSTOP00000025364
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364832,930,789 - 2,967,346 (-)Ensembl
RefSeq Acc Id: XM_005320083   ⟹   XP_005320140
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640143,367,150 - 143,403,705 (+)NCBI
SpeTri2.0NW_0049364832,930,781 - 2,967,309 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005320140 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000008032.3
  ENSSTOP00000025364.1
GenBank Protein KAG3262673 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005320140   ⟸   XM_005320083
- UniProtKB: A0A287CVR7 (UniProtKB/TrEMBL),   I3MCN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000008032   ⟸   ENSSTOT00000008962
RefSeq Acc Id: ENSSTOP00000025364   ⟸   ENSSTOT00000039150
Protein Domains
Aldehyde dehydrogenase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008968 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000008962.3 UniProtKB/TrEMBL
  ENSSTOT00000039150.1 UniProtKB/TrEMBL
InterPro Ald_DH/histidinol_DH UniProtKB/TrEMBL
  Ald_DH_C UniProtKB/TrEMBL
  Ald_DH_CS_CYS UniProtKB/TrEMBL
  Ald_DH_CS_GLU UniProtKB/TrEMBL
  Ald_DH_N UniProtKB/TrEMBL
  Aldehyde_DH_dom UniProtKB/TrEMBL
NCBI Gene Aldh1a3 ENTREZGENE
PANTHER ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3 UniProtKB/TrEMBL
  ALDEHYDE DEHYDROGENASE-RELATED UniProtKB/TrEMBL
Pfam Aldedh UniProtKB/TrEMBL
PROSITE ALDEHYDE_DEHYDR_CYS UniProtKB/TrEMBL
  ALDEHYDE_DEHYDR_GLU UniProtKB/TrEMBL
Superfamily-SCOP SSF53720 UniProtKB/TrEMBL
UniProt A0A287CVR7 ENTREZGENE, UniProtKB/TrEMBL
  I3MCN2 ENTREZGENE, UniProtKB/TrEMBL