Prss56 (serine protease 56) - Rat Genome Database

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Gene: Prss56 (serine protease 56) Ictidomys tridecemlineatus
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Symbol: Prss56
Name: serine protease 56
RGD ID: 12625846
Description: ENCODES a protein that exhibits serine-type endopeptidase activity (inferred); serine-type peptidase activity (inferred); INVOLVED IN camera-type eye development (ortholog); ASSOCIATED WITH angle-closure glaucoma (ortholog); cholangiocarcinoma (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protease, serine 56; protease, serine 56, transcript variant X1; protease, serine 56, transcript variant X2; protease, serine 56, transcript variant X3; protease, serine 56, transcript variant X4; protease, serine 56, transcript variant X5; protease, serine 56, transcript variant X6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303186,363,727 - 186,370,867 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365254,568,802 - 4,574,396 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365254,568,854 - 4,574,332 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Prss56
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303186,363,727 - 186,370,867 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365254,568,802 - 4,574,396 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365254,568,854 - 4,574,332 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRSS56
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382232,520,388 - 232,525,716 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2232,520,388 - 232,525,716 (+)EnsemblGRCh38hg38GRCh38
GRCh372233,385,098 - 233,390,426 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362233,093,553 - 233,098,667 (+)NCBINCBI36Build 36hg18NCBI36
Celera2227,149,624 - 227,154,738 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2225,236,065 - 225,241,318 (+)ENTREZGENEHuRef
CHM1_12233,391,262 - 233,396,515 (+)NCBICHM1_1
T2T-CHM13v2.02233,007,207 - 233,012,535 (+)NCBIT2T-CHM13v2.0
Prss56
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39187,111,002 - 87,116,127 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl187,111,035 - 87,116,127 (+)EnsemblGRCm39 Ensembl
GRCm38187,183,102 - 87,188,405 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,183,313 - 87,188,405 (+)EnsemblGRCm38mm10GRCm38
MGSCv37189,080,068 - 89,084,979 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36189,014,485 - 89,019,578 (+)NCBIMGSCv36mm8
Celera190,156,389 - 90,161,389 (+)NCBICelera
Cytogenetic Map1C5NCBI
cM Map144.07NCBI
Prss56
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,289,984 - 95,307,877 (+)NCBIGRCr8
mRatBN7.2987,842,806 - 87,859,978 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl987,854,805 - 87,859,978 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0994,278,981 - 94,284,111 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,279,155 - 94,283,919 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,002,598 - 94,007,707 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4985,988,860 - 85,993,978 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera985,267,921 - 85,273,051 (+)NCBICelera
Cytogenetic Map9q35NCBI
Prss56
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554533,441,109 - 3,446,090 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554533,440,871 - 3,446,090 (-)NCBIChiLan1.0ChiLan1.0
PRSS56
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213135,125,817 - 135,131,174 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B135,140,780 - 135,146,136 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B119,751,950 - 119,757,308 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B238,670,795 - 238,676,049 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B238,670,931 - 238,675,839 (+)Ensemblpanpan1.1panPan2
PRSS56
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12544,157,247 - 44,165,625 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2544,160,615 - 44,165,625 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2544,651,702 - 44,660,089 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02544,414,634 - 44,423,021 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2544,417,825 - 44,423,024 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12544,340,498 - 44,348,884 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02544,185,781 - 44,194,164 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02544,340,898 - 44,349,293 (+)NCBIUU_Cfam_GSD_1.0
PRSS56
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15133,034,255 - 133,039,367 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115133,033,848 - 133,039,583 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215146,933,579 - 146,939,004 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRSS56
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110118,538,752 - 118,545,759 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10118,540,863 - 118,545,740 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604080,956,137 - 80,961,372 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prss56
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248435,281,709 - 5,287,026 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248435,281,581 - 5,287,060 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSSTOT00000022834   ⟹   ENSSTOP00000022658
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365254,568,802 - 4,574,396 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000041029   ⟹   ENSSTOP00000029023
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365254,568,802 - 4,574,396 (-)Ensembl
RefSeq Acc Id: XM_021727070   ⟹   XP_021582745
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303186,363,727 - 186,370,867 (+)NCBI
SpeTri2.0NW_0049365254,568,854 - 4,574,332 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727071   ⟹   XP_021582746
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303186,363,727 - 186,370,867 (+)NCBI
SpeTri2.0NW_0049365254,568,854 - 4,574,329 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727072   ⟹   XP_021582747
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303186,363,727 - 186,370,867 (+)NCBI
SpeTri2.0NW_0049365254,568,854 - 4,574,332 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727073   ⟹   XP_021582748
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303186,363,727 - 186,370,867 (+)NCBI
SpeTri2.0NW_0049365254,568,854 - 4,574,329 (-)NCBI
Sequence:
RefSeq Acc Id: XP_021582747   ⟸   XM_021727072
- Peptide Label: isoform X3
- UniProtKB: A0A287D662 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021582745   ⟸   XM_021727070
- Peptide Label: isoform X1
- UniProtKB: A0A287D662 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021582748   ⟸   XM_021727073
- Peptide Label: isoform X4
- UniProtKB: I3NE61 (UniProtKB/TrEMBL),   A0A287D662 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021582746   ⟸   XM_021727071
- Peptide Label: isoform X2
- UniProtKB: A0A287D662 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000029023   ⟸   ENSSTOT00000041029
RefSeq Acc Id: ENSSTOP00000022658   ⟸   ENSSTOT00000022834
Protein Domains
Peptidase S1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000021941 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000022834.2 UniProtKB/TrEMBL
  ENSSTOT00000041029.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
NCBI Gene Prss56 ENTREZGENE
PANTHER HYALURONAN-BINDING PROTEIN 2 UniProtKB/TrEMBL
  TRYPSIN-RELATED UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt A0A287D662 ENTREZGENE, UniProtKB/TrEMBL
  I3NE61 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-01-23 Prss56  serine protease 56    protease, serine 56  Symbol and/or name change 5135510 APPROVED