Lrit2 (leucine rich repeat, Ig-like and transmembrane domains 2) - Rat Genome Database

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Gene: Lrit2 (leucine rich repeat, Ig-like and transmembrane domains 2) Ictidomys tridecemlineatus
Analyze
Symbol: Lrit2
Name: leucine rich repeat, Ig-like and transmembrane domains 2
RGD ID: 12624908
Description: ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721346,250,847 - 46,255,149 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936767833,890 - 837,647 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936767833,219 - 838,283 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Lrit2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721346,250,847 - 46,255,149 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936767833,890 - 837,647 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936767833,219 - 838,283 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRIT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381084,220,485 - 84,225,589 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1084,220,571 - 84,225,544 (-)EnsemblGRCh38hg38GRCh38
GRCh371085,980,241 - 85,985,345 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361085,970,221 - 85,975,264 (-)NCBINCBI36Build 36hg18NCBI36
Celera1079,975,750 - 79,980,793 (-)NCBICelera
Cytogenetic Map10q23.1NCBI
HuRef1079,825,720 - 79,830,763 (-)NCBIHuRef
CHM1_11086,262,008 - 86,267,051 (-)NCBICHM1_1
T2T-CHM13v2.01085,099,011 - 85,104,115 (-)NCBIT2T-CHM13v2.0
Lrit2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391436,784,923 - 36,795,700 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1436,789,886 - 36,795,700 (+)EnsemblGRCm39 Ensembl
GRCm381437,064,433 - 37,073,743 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1437,067,929 - 37,073,743 (+)EnsemblGRCm38mm10GRCm38
MGSCv371437,881,235 - 37,886,921 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361435,979,290 - 35,984,976 (+)NCBIMGSCv36mm8
Celera1433,279,110 - 33,284,754 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1421.29NCBI
Lrit2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81612,855,257 - 12,860,289 (+)NCBIGRCr8
mRatBN7.21612,834,996 - 12,840,028 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1612,835,051 - 12,839,482 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1612,779,340 - 12,783,776 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01613,924,075 - 13,928,511 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01612,771,836 - 12,776,271 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01614,315,980 - 14,325,053 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1614,319,777 - 14,324,208 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01614,220,595 - 14,226,565 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41613,275,634 - 13,280,065 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1613,093,227 - 13,097,658 (+)NCBICelera
Cytogenetic Map16p14NCBI
Lrit2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555103,732,436 - 3,736,557 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555103,732,436 - 3,736,557 (-)NCBIChiLan1.0ChiLan1.0
LRIT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2896,201,349 - 96,207,644 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11096,206,669 - 96,212,964 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01080,636,045 - 80,641,129 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11084,205,958 - 84,211,052 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1084,205,967 - 84,211,052 (-)Ensemblpanpan1.1panPan2
LRIT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1432,464,825 - 32,468,988 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl432,464,825 - 32,468,988 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha432,450,256 - 32,454,419 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0432,780,362 - 32,784,526 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl432,780,362 - 32,784,526 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1432,642,970 - 32,647,135 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0432,835,251 - 32,839,416 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0433,331,859 - 33,336,023 (-)NCBIUU_Cfam_GSD_1.0
LRIT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1485,460,549 - 85,465,274 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11485,461,325 - 85,465,274 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21492,266,178 - 92,270,127 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRIT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1947,603,280 - 47,610,230 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl947,604,868 - 47,608,805 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660487,781,490 - 7,786,836 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrit2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248412,804,741 - 2,808,760 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248412,804,741 - 2,808,760 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021719994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010002273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000010343   ⟹   ENSSTOP00000009281
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936767833,890 - 837,647 (-)Ensembl
RefSeq Acc Id: XM_021719994   ⟹   XP_021575669
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721346,250,847 - 46,255,149 (+)NCBI
SpeTri2.0NW_004936767833,219 - 838,283 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_021575669 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000009281.3
GenBank Protein KAG3264564 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021575669   ⟸   XM_021719994
- UniProtKB: I3MFB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000009281   ⟸   ENSSTOT00000010343
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000010349 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000010343.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  Prtase_inh_Kunz-CS UniProtKB/TrEMBL
NCBI Gene Lrit2 ENTREZGENE
PANTHER LEUCINE-RICH REPEAT, IMMUNOGLOBULIN-LIKE DOMAIN AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  SYNAPTIC ADHESION-LIKE MOLECULE SALM UniProtKB/TrEMBL
Pfam Ig_3 UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
PROSITE BPTI_KUNITZ_1 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  LRR_BAC UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
UniProt I3MFB5 ENTREZGENE, UniProtKB/TrEMBL