G3bp1 (G3BP stress granule assembly factor 1) - Rat Genome Database

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Gene: G3bp1 (G3BP stress granule assembly factor 1) Ictidomys tridecemlineatus
Analyze
Symbol: G3bp1
Name: G3BP stress granule assembly factor 1
RGD ID: 12623378
Description: ENCODES a protein that exhibits DNA helicase activity (inferred); DNA/RNA helicase activity (inferred); molecular condensate scaffold activity (inferred); INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); ASSOCIATED WITH Disease Progression (ortholog); familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); FOUND IN cytoplasmic stress granule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras GTPase-activating protein-binding protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213112,467,088 - 112,499,763 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651510,916,442 - 10,949,085 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651510,916,442 - 10,949,080 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
G3bp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213112,467,088 - 112,499,763 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651510,916,442 - 10,949,085 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651510,916,442 - 10,949,080 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
G3BP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385151,771,954 - 151,812,785 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5151,771,045 - 151,812,911 (+)EnsemblGRCh38hg38GRCh38
GRCh375151,151,515 - 151,192,346 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365151,131,669 - 151,165,108 (+)NCBINCBI36Build 36hg18NCBI36
Celera5147,232,867 - 147,266,308 (+)NCBICelera
Cytogenetic Map5q33.1NCBI
HuRef5146,296,870 - 146,330,324 (+)NCBIHuRef
CHM1_15150,583,918 - 150,617,337 (+)NCBICHM1_1
T2T-CHM13v2.05152,310,934 - 152,351,769 (+)NCBIT2T-CHM13v2.0
G3bp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,360,521 - 55,391,722 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1155,360,511 - 55,395,664 (+)EnsemblGRCm39 Ensembl
GRCm381155,469,657 - 55,500,888 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1155,469,685 - 55,504,838 (+)EnsemblGRCm38mm10GRCm38
MGSCv371155,283,254 - 55,314,389 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361155,313,175 - 55,344,310 (+)NCBIMGSCv36mm8
Celera1160,271,641 - 60,286,911 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1133.09NCBI
G3bp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81040,087,533 - 40,120,931 (+)NCBIGRCr8
mRatBN7.21039,586,864 - 39,620,268 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1039,586,864 - 39,620,268 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1044,270,665 - 44,304,038 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01043,760,770 - 43,794,148 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01039,264,441 - 39,297,820 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01040,812,858 - 40,846,252 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1040,812,858 - 40,846,252 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01040,644,334 - 40,678,457 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41040,880,198 - 40,913,723 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11040,922,239 - 40,922,700 (+)NCBI
Celera1038,918,605 - 38,949,887 (+)NCBICelera
Cytogenetic Map10q22NCBI
G3bp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554086,197,361 - 6,215,979 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554086,197,988 - 6,223,135 (+)NCBIChiLan1.0ChiLan1.0
G3BP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24147,000,002 - 147,033,451 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15145,139,497 - 145,172,996 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05147,195,100 - 147,234,576 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15153,197,988 - 153,237,329 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5153,197,813 - 153,230,414 (+)Ensemblpanpan1.1panPan2
G3BP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1457,541,627 - 57,585,375 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl457,481,908 - 57,585,241 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha457,361,381 - 57,405,136 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0457,984,264 - 58,028,046 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl457,962,892 - 58,027,993 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1457,800,420 - 57,844,163 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0457,898,867 - 57,942,698 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0458,402,150 - 58,445,909 (-)NCBIUU_Cfam_GSD_1.0
G3BP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1671,236,339 - 71,276,078 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11671,236,025 - 71,276,111 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21677,426,673 - 77,442,846 (-)NCBISscrofa10.2Sscrofa10.2susScr3
G3BP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12354,335,996 - 54,369,956 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2354,336,113 - 54,368,674 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603423,329,228 - 23,368,946 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
G3bp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473337,253,054 - 37,274,067 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473337,246,989 - 37,279,818 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005325475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010002273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000015937   ⟹   ENSSTOP00000014260
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493651510,916,442 - 10,949,085 (-)Ensembl
RefSeq Acc Id: XM_005325475   ⟹   XP_005325532
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213112,467,088 - 112,499,763 (-)NCBI
SpeTri2.0NW_00493651510,916,442 - 10,949,080 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005325532 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000014260.2
GenBank Protein KAG3265434 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005325532   ⟸   XM_005325475
- UniProtKB: I3MQL7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000014260   ⟸   ENSSTOT00000015937
Protein Domains
NTF2   RRM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015928 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015937.3 UniProtKB/TrEMBL
Gene3D-CATH 3.10.450.50 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
InterPro G3BP1_RRM UniProtKB/TrEMBL
  NTF2 UniProtKB/TrEMBL
  NTF2-like_dom_sf UniProtKB/TrEMBL
  Nuclear_transport_factor_2_euk UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  Ras_GTPase_bind_prot UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
NCBI Gene G3bp1 ENTREZGENE
PANTHER PTHR10693 UniProtKB/TrEMBL
  PTHR10693:SF21 UniProtKB/TrEMBL
Pfam NTF2 UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
PROSITE NTF2_DOMAIN UniProtKB/TrEMBL
  RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54427 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt I3MQL7 ENTREZGENE, UniProtKB/TrEMBL