Apip (APAF1 interacting protein) - Rat Genome Database

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Gene: Apip (APAF1 interacting protein) Ictidomys tridecemlineatus
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Symbol: Apip
Name: APAF1 interacting protein
RGD ID: 12623240
Description: ENCODES a protein that exhibits identical protein binding (inferred); methylthioribulose 1-phosphate dehydratase activity (inferred); zinc ion binding (inferred); INVOLVED IN apoptotic process (ortholog); negative regulation of apoptotic process (ortholog); ASSOCIATED WITH intellectual disability (ortholog); Pyruvate Dehydrogenase E3-Binding Protein Deficiency (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC101975600; methylthioribulose-1-phosphate dehydratase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494730,091,219 - 30,114,204 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365333,216,187 - 3,238,776 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365333,216,020 - 3,238,999 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Apip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494730,091,219 - 30,114,204 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365333,216,187 - 3,238,776 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365333,216,020 - 3,238,999 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381134,882,295 - 34,916,379 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1134,853,094 - 34,916,379 (-)EnsemblGRCh38hg38GRCh38
GRCh371134,903,842 - 34,937,926 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361134,860,421 - 34,894,484 (-)NCBINCBI36Build 36hg18NCBI36
Celera1135,051,185 - 35,085,276 (-)NCBICelera
Cytogenetic Map11p13NCBI
HuRef1134,602,325 - 34,636,417 (-)NCBIHuRef
CHM1_11134,902,113 - 34,936,196 (-)NCBICHM1_1
T2T-CHM13v2.01135,020,271 - 35,054,314 (-)NCBIT2T-CHM13v2.0
Apip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392102,904,020 - 102,922,994 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2102,904,020 - 102,922,989 (+)EnsemblGRCm39 Ensembl
GRCm382103,073,675 - 103,092,649 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2103,073,675 - 103,092,644 (+)EnsemblGRCm38mm10GRCm38
MGSCv372102,913,832 - 102,932,806 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362102,874,514 - 102,893,460 (+)NCBIMGSCv36mm8
Celera2104,317,769 - 104,336,727 (+)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.29NCBI
Apip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83109,886,919 - 109,913,295 (+)NCBIGRCr8
mRatBN7.2389,431,964 - 89,458,000 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl389,432,037 - 89,458,340 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx392,931,217 - 92,957,295 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03101,530,251 - 101,556,331 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0399,359,187 - 99,385,302 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0392,969,128 - 92,998,104 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl392,969,141 - 92,995,483 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0399,612,110 - 99,640,878 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4388,306,123 - 88,332,800 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera388,509,653 - 88,535,688 (+)NCBICelera
Cytogenetic Map3q32NCBI
Apip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542211,405,721 - 11,429,146 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542211,405,721 - 11,426,700 (+)NCBIChiLan1.0ChiLan1.0
APIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2937,103,066 - 37,137,097 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11137,107,771 - 37,141,802 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01134,855,437 - 34,889,486 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11134,730,671 - 34,764,732 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1134,730,671 - 34,764,732 (-)Ensemblpanpan1.1panPan2
APIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11833,012,049 - 33,033,453 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1833,011,121 - 33,033,435 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1832,617,866 - 32,639,261 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01833,623,160 - 33,644,563 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11833,183,124 - 33,204,482 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01832,774,401 - 32,795,973 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01833,409,813 - 33,431,215 (+)NCBIUU_Cfam_GSD_1.0
APIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl226,095,038 - 26,115,464 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1226,095,020 - 26,115,462 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2228,461,921 - 28,482,434 (+)NCBISscrofa10.2Sscrofa10.2susScr3
APIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1130,344,658 - 30,374,741 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl130,344,690 - 30,374,737 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038127,458,535 - 127,492,516 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Apip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476712,257,597 - 12,280,154 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476712,257,591 - 12,285,968 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000004383   ⟹   ENSSTOP00000003932
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365333,216,187 - 3,238,776 (+)Ensembl
RefSeq Acc Id: XM_040283731   ⟹   XP_040139665
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494730,091,219 - 30,114,204 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040139665 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000003932.3
GenBank Protein KAG3285475 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_040139665   ⟸   XM_040283731
- UniProtKB: I3M448 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000003932   ⟸   ENSSTOT00000004383

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004390 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004383.3 UniProtKB/TrEMBL
Gene3D-CATH 3.40.225.10 UniProtKB/TrEMBL
InterPro Aldolase_II/adducin_N UniProtKB/TrEMBL
  Aldolase_II/adducin_N_sf UniProtKB/TrEMBL
NCBI Gene Apip ENTREZGENE
PANTHER METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE UniProtKB/TrEMBL
  PTHR10640 UniProtKB/TrEMBL
Pfam Aldolase_II UniProtKB/TrEMBL
SMART Aldolase_II UniProtKB/TrEMBL
Superfamily-SCOP SSF53639 UniProtKB/TrEMBL
UniProt I3M448 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-09 Apip  APAF1 interacting protein  LOC101975600  APAF1 interacting protein  Symbol and/or name change 5135510 APPROVED
2021-03-26 LOC101975600  APAF1 interacting protein  Apip  APAF1 interacting protein  Symbol and/or name change 5135510 APPROVED