Ywhae (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon) - Rat Genome Database

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Gene: Ywhae (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon) Ictidomys tridecemlineatus
Analyze
Symbol: Ywhae
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
RGD ID: 12622655
Description: ENCODES a protein that exhibits calcium channel inhibitor activity (ortholog); calcium channel regulator activity (ortholog); enzyme binding (ortholog); INVOLVED IN cellular response to heat (ortholog); cerebral cortex development (ortholog); cytoplasmic pattern recognition receptor signaling pathway (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; insulin-like growth factor signaling pathway; mTOR signaling pathway; ASSOCIATED WITH chromosome 17p13.3 duplication syndrome (ortholog); Hirschsprung's disease (ortholog); left ventricular noncompaction (ortholog); FOUND IN axon (ortholog); central region of growth cone (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 14-3-3 protein epsilon; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560244,640,329 - 44,680,511 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365387,517,271 - 7,558,854 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365387,518,283 - 7,558,458 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ywhae
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560244,640,329 - 44,680,511 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365387,517,271 - 7,558,854 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365387,518,283 - 7,558,458 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
YWHAE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38171,344,275 - 1,400,222 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl171,344,275 - 1,400,222 (-)EnsemblGRCh38hg38GRCh38
GRCh37171,247,569 - 1,303,516 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36171,194,590 - 1,250,267 (-)NCBINCBI36Build 36hg18NCBI36
Build 34171,194,594 - 1,250,267NCBI
Celera171,261,362 - 1,317,358 (-)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef171,148,526 - 1,204,512 (-)NCBIHuRef
CHM1_1171,256,607 - 1,312,325 (-)NCBICHM1_1
T2T-CHM13v2.0171,232,983 - 1,288,946 (-)NCBIT2T-CHM13v2.0
Ywhae
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,620,121 - 75,656,667 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1175,623,695 - 75,656,671 (+)EnsemblGRCm39 Ensembl
GRCm381175,732,887 - 75,765,841 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,732,869 - 75,765,845 (+)EnsemblGRCm38mm10GRCm38
MGSCv371175,546,389 - 75,579,343 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361175,549,134 - 75,582,033 (+)NCBIMGSCv36mm8
Celera1183,242,083 - 83,275,058 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.92NCBI
Ywhae
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81061,082,934 - 61,120,618 (+)NCBIGRCr8
mRatBN7.21060,584,665 - 60,622,352 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1060,584,652 - 60,671,589 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1065,231,325 - 65,269,017 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01064,736,744 - 64,774,435 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01060,199,320 - 60,237,010 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01063,884,338 - 63,921,709 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1063,884,338 - 63,921,709 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01064,084,793 - 64,121,811 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41063,072,128 - 63,109,833 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11063,085,750 - 63,123,456 (+)NCBI
Celera1059,610,373 - 59,647,466 (+)NCBICelera
Cytogenetic Map10q24NCBI
Ywhae
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554811,752,778 - 1,808,583 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554811,752,778 - 1,805,700 (+)NCBIChiLan1.0ChiLan1.0
YWHAE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,919,694 - 8,974,995 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11710,886,159 - 10,941,234 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0171,332,004 - 1,387,120 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1171,229,080 - 1,285,470 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl171,229,080 - 1,285,470 (-)Ensemblpanpan1.1panPan2
YWHAE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1945,506,830 - 45,562,081 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl945,507,282 - 45,562,086 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha944,657,120 - 44,712,199 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0946,326,319 - 46,383,522 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl946,324,061 - 46,383,527 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1945,103,428 - 45,158,578 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0945,397,360 - 45,452,634 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0945,476,152 - 45,531,404 (-)NCBIUU_Cfam_GSD_1.0
YWHAE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1247,600,745 - 47,645,301 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11247,601,133 - 47,645,327 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
YWHAE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1161,031,840 - 1,086,950 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl161,035,250 - 1,087,013 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605920,911,242 - 20,971,138 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ywhae
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247864,080,427 - 4,135,459 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247864,080,650 - 4,135,200 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000005083   ⟹   ENSSTOP00000004563
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365387,517,271 - 7,558,854 (-)Ensembl
RefSeq Acc Id: XM_005327890   ⟹   XP_005327947
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560244,640,329 - 44,680,509 (-)NCBI
SpeTri2.0NW_0049365387,518,283 - 7,558,458 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013359808   ⟹   XP_013215262
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560244,640,329 - 44,680,511 (-)NCBI
SpeTri2.0NW_0049365387,518,283 - 7,558,458 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005327947 (Get FASTA)   NCBI Sequence Viewer  
  XP_013215262 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000004563.3
GenBank Protein KAG3269716 (Get FASTA)   NCBI Sequence Viewer  
  KAG3269717 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005327947   ⟸   XM_005327890
- Peptide Label: isoform X1
- UniProtKB: I3M5F9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013215262   ⟸   XM_013359808
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSTOP00000004563   ⟸   ENSSTOT00000005083
Protein Domains
14-3-3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000005084 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000005083.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.190.20 UniProtKB/TrEMBL
InterPro 14-3-3 UniProtKB/TrEMBL
  14-3-3_CS UniProtKB/TrEMBL
  14-3-3_dom_sf UniProtKB/TrEMBL
  14-3-3_domain UniProtKB/TrEMBL
NCBI Gene Ywhae ENTREZGENE
PANTHER 14-3-3 PROTEIN EPSILON UniProtKB/TrEMBL
  PTHR18860 UniProtKB/TrEMBL
Pfam 14-3-3 UniProtKB/TrEMBL
PIRSF 14-3-3 UniProtKB/TrEMBL
PRINTS 1433ZETA UniProtKB/TrEMBL
PROSITE 1433_1 UniProtKB/TrEMBL
  1433_2 UniProtKB/TrEMBL
SMART 14_3_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48445 UniProtKB/TrEMBL
UniProt I3M5F9 ENTREZGENE, UniProtKB/TrEMBL