Mmp17 (matrix metallopeptidase 17) - Rat Genome Database

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Gene: Mmp17 (matrix metallopeptidase 17) Ictidomys tridecemlineatus
Analyze
Symbol: Mmp17
Name: matrix metallopeptidase 17
RGD ID: 12621232
Description: ENCODES a protein that exhibits metal ion binding (inferred); metalloendopeptidase activity (inferred); metallopeptidase activity (inferred); INVOLVED IN drinking behavior (ortholog); kidney development (ortholog); FOUND IN extracellular matrix (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: matrix metalloproteinase-17
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118122,568,921 - 122,590,193 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366602,139,129 - 2,150,741 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366602,139,777 - 2,152,159 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mmp17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118122,568,921 - 122,590,193 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366602,139,129 - 2,150,741 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366602,139,777 - 2,152,159 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMP17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812131,828,393 - 131,851,771 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12131,828,393 - 131,851,783 (+)EnsemblGRCh38hg38GRCh38
GRCh3712132,312,938 - 132,336,316 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612130,878,894 - 130,902,272 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412130,979,170 - 131,002,546NCBI
Celera12131,939,471 - 131,953,072 (+)NCBICelera
Cytogenetic Map12q24.33NCBI
HuRef12129,198,895 - 129,222,033 (+)NCBIHuRef
CHM1_112132,133,920 - 132,157,125 (+)NCBICHM1_1
T2T-CHM13v2.012131,872,417 - 131,895,761 (+)NCBIT2T-CHM13v2.0
Mmp17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395129,661,215 - 129,688,163 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5129,661,233 - 129,688,163 (+)EnsemblGRCm39 Ensembl
GRCm385129,584,151 - 129,611,099 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5129,584,169 - 129,611,099 (+)EnsemblGRCm38mm10GRCm38
MGSCv375130,090,089 - 130,114,086 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365129,898,922 - 129,922,919 (+)NCBIMGSCv36mm8
Celera5126,627,110 - 126,651,274 (+)NCBICelera
Cytogenetic Map5G1.3NCBI
cM Map568.18NCBI
Mmp17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81232,710,504 - 32,735,418 (-)NCBIGRCr8
mRatBN7.21227,074,398 - 27,099,317 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1227,074,409 - 27,099,316 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1228,210,833 - 28,235,729 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01228,821,391 - 28,846,290 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01227,882,871 - 27,907,767 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01230,353,874 - 30,356,526 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.01230,701,900 - 30,728,683 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1230,702,571 - 30,728,655 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,636,484 - 32,663,678 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41228,142,947 - 28,168,483 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11228,007,827 - 28,031,804 (-)NCBI
Celera1228,778,275 - 28,803,185 (-)NCBICelera
Cytogenetic Map12q13NCBI
Mmp17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955482789,968 - 797,301 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955482788,921 - 797,301 (-)NCBIChiLan1.0ChiLan1.0
MMP17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210139,918,156 - 139,943,785 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112139,914,706 - 139,940,301 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012129,481,501 - 129,505,696 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112133,922,882 - 133,936,152 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12133,922,882 - 133,936,152 (+)Ensemblpanpan1.1panPan2
MMP17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1261,008,651 - 1,019,131 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl261,009,109 - 1,018,662 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha261,054,484 - 1,073,216 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0261,072,479 - 1,091,195 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl261,072,934 - 1,091,431 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1261,009,626 - 1,028,354 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0261,106,771 - 1,124,956 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0261,029,400 - 1,048,084 (-)NCBIUU_Cfam_GSD_1.0
MMP17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1423,481,227 - 23,506,919 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11423,481,220 - 23,506,936 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21424,946,584 - 24,972,449 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MMP17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111127,204,811 - 127,229,202 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11127,214,890 - 127,230,731 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037117,730,300 - 117,813,072 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mmp17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474727,659,060 - 27,670,447 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474727,658,997 - 27,671,377 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005336367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSTOT00000004801   ⟹   ENSSTOP00000004312
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366602,139,129 - 2,150,741 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000033816   ⟹   ENSSTOP00000029083
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366602,139,129 - 2,150,741 (+)Ensembl
RefSeq Acc Id: XM_005336367   ⟹   XP_005336424
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118122,568,921 - 122,590,193 (-)NCBI
SpeTri2.0NW_0049366602,139,777 - 2,152,159 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005336424 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000004312.3
  ENSSTOP00000029083.1
GenBank Protein KAG3278581 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005336424   ⟸   XM_005336367
- UniProtKB: A0A287D6C2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000029083   ⟸   ENSSTOT00000033816
Ensembl Acc Id: ENSSTOP00000004312   ⟸   ENSSTOT00000004801
Protein Domains
Peptidase metallopeptidase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004804 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004801.3 UniProtKB/TrEMBL
  ENSSTOT00000033816.1 UniProtKB/TrEMBL
Gene3D-CATH 2.110.10.10 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro Hemopexin-like_dom UniProtKB/TrEMBL
  Hemopexin-like_dom_sf UniProtKB/TrEMBL
  Hemopexin-like_repeat UniProtKB/TrEMBL
  M10A_MMP UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Pept_M10_metallopeptidase UniProtKB/TrEMBL
  Pept_M10A UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/TrEMBL
  Peptidoglycan-bd-like UniProtKB/TrEMBL
  PGBD-like_sf UniProtKB/TrEMBL
NCBI Gene Mmp17 ENTREZGENE
PANTHER MATRIX METALLOPROTEINASE UniProtKB/TrEMBL
  PTHR10201:SF21 UniProtKB/TrEMBL
Pfam Hemopexin UniProtKB/TrEMBL
  Peptidase_M10 UniProtKB/TrEMBL
  PG_binding_1 UniProtKB/TrEMBL
PIRSF Peptidase_M10A_matrix UniProtKB/TrEMBL
PRINTS MATRIXIN UniProtKB/TrEMBL
PROSITE HEMOPEXIN_2 UniProtKB/TrEMBL
SMART SM00120 UniProtKB/TrEMBL
  ZnMc UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF47090 UniProtKB/TrEMBL
  SSF50923 UniProtKB/TrEMBL
UniProt A0A287D6C2 ENTREZGENE, UniProtKB/TrEMBL
  I3M4W7_ICTTR UniProtKB/TrEMBL