Itga4 (integrin subunit alpha 4) - Rat Genome Database

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Gene: Itga4 (integrin subunit alpha 4) Ictidomys tridecemlineatus
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Symbol: Itga4
Name: integrin subunit alpha 4
RGD ID: 12620996
Description: ENCODES a protein that exhibits antigen binding (ortholog); C-X3-C chemokine binding (ortholog); cell adhesion molecule binding (ortholog); INVOLVED IN axonogenesis involved in innervation (ortholog); blood vessel remodeling (ortholog); cell adhesion (ortholog); PARTICIPATES IN altered integrin mediated signaling pathway; integrin mediated signaling pathway; pancreatic cancer pathway; ASSOCIATED WITH anti-basement membrane glomerulonephritis (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN cell surface (ortholog); cell-cell junction (ortholog); external side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: integrin alpha-4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303141,661,380 - 141,739,750 (+)NCBI
SpeTri2.0NW_00493650910,215,283 - 10,293,653 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Itga4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303141,661,380 - 141,739,750 (+)NCBI
SpeTri2.0NW_00493650910,215,283 - 10,293,653 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITGA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2181,457,202 - 181,538,940 (+)EnsemblGRCh38hg38GRCh38
GRCh382181,457,205 - 181,538,940 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372182,321,932 - 182,403,667 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362182,029,864 - 182,110,719 (+)NCBINCBI36hg18NCBI36
Build 342182,146,716 - 182,226,420NCBI
Celera2175,917,712 - 175,998,559 (+)NCBI
Cytogenetic Map2q31.3NCBI
HuRef2174,178,675 - 174,259,339 (+)NCBIHuRef
CHM1_12182,327,169 - 182,408,848 (+)NCBICHM1_1
Itga4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39279,084,767 - 79,163,458 (+)NCBIGRCm39mm39
GRCm39 Ensembl279,085,770 - 79,163,467 (+)Ensembl
GRCm38279,255,426 - 79,333,114 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl279,255,426 - 79,333,123 (+)EnsemblGRCm38mm10GRCm38
MGSCv37279,095,583 - 79,173,271 (+)NCBIGRCm37mm9NCBIm37
MGSCv36279,056,484 - 79,131,613 (+)NCBImm8
Celera280,914,099 - 80,991,875 (+)NCBICelera
Cytogenetic Map2C3NCBI
cM Map247.38NCBI
Itga4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2364,162,764 - 64,235,010 (+)NCBI
Rnor_6.0 Ensembl366,193,059 - 66,263,960 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0366,178,745 - 66,265,547 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0372,754,339 - 72,825,872 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4362,024,747 - 62,097,456 (+)NCBIRGSC3.4rn4RGSC3.4
Celera363,623,691 - 63,694,098 (+)NCBICelera
Cytogenetic Map3q24NCBI
Itga4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540315,723,785 - 15,807,111 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540315,726,296 - 15,807,055 (-)NCBIChiLan1.0ChiLan1.0
ITGA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B186,530,187 - 186,613,398 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B186,530,187 - 186,612,203 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B68,719,376 - 68,802,488 (+)NCBIMhudiblu_PPA_v0panPan3
ITGA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13624,670,464 - 24,686,719 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3624,653,408 - 24,729,057 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3624,675,932 - 24,755,430 (+)NCBI
ROS_Cfam_1.03624,815,313 - 24,895,039 (+)NCBI
UMICH_Zoey_3.13624,904,710 - 24,984,278 (+)NCBI
UNSW_CanFamBas_1.03624,869,937 - 24,949,662 (+)NCBI
UU_Cfam_GSD_1.03625,004,898 - 25,084,914 (+)NCBI
ITGA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1586,947,021 - 87,029,777 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11586,942,054 - 87,028,428 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21596,521,473 - 96,602,512 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ITGA4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11066,984,687 - 67,063,158 (+)NCBI
ChlSab1.1 Ensembl1066,984,887 - 67,061,636 (+)Ensembl
Itga4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248443,264,794 - 3,353,355 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005324694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005324694   ⟹   XP_005324751
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303141,661,380 - 141,739,750 (+)NCBI
SpeTri2.0NW_00493650910,215,283 - 10,293,653 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005324751 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005324751   ⟸   XM_005324694
- UniProtKB: I3MED3 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Integrin_alpha2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000009849 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000008842 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000009860 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.130 UniProtKB/TrEMBL
InterPro FG-GAP UniProtKB/TrEMBL
  Int_alpha_beta-p UniProtKB/TrEMBL
  Integrin_alpha UniProtKB/TrEMBL
  Integrin_alpha-2 UniProtKB/TrEMBL
  Integrin_alpha_C_CS UniProtKB/TrEMBL
  Integrin_alpha_N UniProtKB/TrEMBL
  Integrin_dom_sf UniProtKB/TrEMBL
NCBI Gene Itga4 ENTREZGENE
Pfam FG-GAP UniProtKB/TrEMBL
  Integrin_alpha2 UniProtKB/TrEMBL
PRINTS INTEGRINA UniProtKB/TrEMBL
PROSITE FG_GAP UniProtKB/TrEMBL
  INTEGRIN_ALPHA UniProtKB/TrEMBL
SMART Int_alpha UniProtKB/TrEMBL
Superfamily-SCOP SSF69179 UniProtKB/TrEMBL
UniProt I3MED3 ENTREZGENE, UniProtKB/TrEMBL