Fcer1a (Fc fragment of IgE receptor Ia)

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Gene: Fcer1a (Fc fragment of IgE receptor Ia) Ictidomys tridecemlineatus

Analyze

Symbol:

Fcer1a

Name:

Fc fragment of IgE receptor Ia

RGD ID:

12616261

Description:

ENCODES a protein that exhibits IgE binding (ortholog); IgE receptor activity (ortholog); INVOLVED IN activation of JUN kinase activity (ortholog); activation of MAPK activity (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH asthma (ortholog); drug allergy (ortholog); Drug Eruptions (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); integral component of plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

high affinity immunoglobulin epsilon receptor subunit alpha

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Dog

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936740	1,201,370 - 1,206,871 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asthma (ISO)

drug allergy (ISO)

Drug Eruptions (ISO)

rhinitis (ISO)

urticaria (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activation of JUN kinase activity (ISO)

activation of MAPK activity (ISO)

cell surface receptor signaling pathway (ISO)

leukotriene biosynthetic process (ISO)

positive regulation of calcium-mediated signaling (ISO)

positive regulation of granulocyte macrophage colony-stimulating factor production (ISO)

positive regulation of interleukin-3 production (ISO)

positive regulation of mast cell degranulation (ISO)

positive regulation of peptidyl-tyrosine phosphorylation (ISO)

positive regulation of type I hypersensitivity (ISO)

serotonin secretion (ISO)

signal transduction (ISO)

Cellular Component

cell surface (ISO)

external side of plasma membrane (ISO)

integral component of plasma membrane (ISO)

Molecular Function

IgE binding (ISO)

IgE receptor activity (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Fc epsilon receptor mediated signaling pathway (ISO)

References

Genomics

Comparative Map Data

Fcer1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936740	1,201,370 - 1,206,871 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FCER1A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	1	159,289,714 - 159,308,224 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	1	159,283,575 - 159,308,202 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	1	159,253,365 - 159,277,992 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	157,526,128 - 157,544,638 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	1	156,072,576 - 156,091,086	NCBI
Celera	1	132,329,745 - 132,348,256 (+)	NCBI
Cytogenetic Map	1	q23.2	NCBI
HuRef	1	130,610,827 - 130,635,025 (+)	NCBI		HuRef
CHM1_1	1	160,649,107 - 160,673,443 (+)	NCBI		CHM1_1

Fcer1a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	173,048,836 - 173,054,799 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	1	173,048,851 - 173,054,781 (-)	Ensembl
GRCm38	1	173,221,269 - 173,227,232 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	173,221,284 - 173,227,214 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	175,151,402 - 175,157,360 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	1	175,057,959 - 175,063,889 (-)	NCBI			mm8
Celera	1	176,073,170 - 176,079,126 (-)	NCBI		Celera
Cytogenetic Map	1	H3	NCBI
cM Map	1	80.33	NCBI

Fcer1a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	85,686,099 - 85,692,394 (-)	NCBI
Rnor_6.0 Ensembl	13	91,730,925 - 91,737,053 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	13	91,727,253 - 91,737,106 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	13	96,245,261 - 96,251,522 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	89,429,982 - 89,436,507 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	13	89,618,865 - 89,625,338 (-)	NCBI
Celera	13	85,289,763 - 85,295,958 (-)	NCBI		Celera
RH 3.4 Map	13	566.1	RGD
Cytogenetic Map	13	q24	NCBI

Fcer1a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	11,094,788 - 11,101,173 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	11,094,792 - 11,101,191 (+)	NCBI	ChiLan1.0	ChiLan1.0

FCER1A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	138,439,921 - 138,458,258 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	138,439,921 - 138,458,258 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	1	134,655,230 - 134,660,961 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

FCER1A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	38	22,683,477 - 22,690,763 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	38	22,683,478 - 22,688,842 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

FCER1A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	91,118,879 - 91,125,437 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	91,118,867 - 91,125,448 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	99,069,615 - 99,075,656 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FCER1A
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	4,635,316 - 4,640,787 (-)	NCBI
ChlSab1.1 Ensembl	20	4,635,328 - 4,640,590 (-)	Ensembl

Fcer1a
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624794	2,003,031 - 2,008,930 (-)	NCBI

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005339418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGTP01101631	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

XM_005339418 ⟹ XP_005339475

RefSeq Status:

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0	NW_004936740	1,201,370 - 1,206,871 (-)	NCBI

Sequence:

show sequence

ATGGATGTAGATCTCATCCCCACACCCAGATCCCAGTACTGTGGAGTCCCAGAAGACTGGGGAG
AGATGCTAACTTCTCCTTTCTGGACTTTTGCAGCTCTGGCTGGCACGCTAACAGGCAATAGAAA
ATCTATTCTGACCTTGAACCCCCCATGGAATAGAATTTTTAGAGGAGAGAATGTGACTCTCGAA
TGTAAAGGGAATAATTTCACCGAGGACAGCCACACTGTGTGGACCCATAATGGCACCATTTCAG
AAGTGACAACTTCAAAATGGAGCATCGTGAATGCCACCTATCAACACAGTGGGAAATACACATG
TCATGGCCGAAATTTTTACAAGAGTAAACCTGTGTACTTGGAAGTGATCAGTGACTGGATGCTC
CTCCAGGCCTCTGCTGAGCAGGTGTTGGAAGGGGAGTCGCTCTTCCTCAGGTGCCACGGTTGGA
GAAACTGGAAGATCAGAAAGGTGATCTACTACAAGAATGACATGGCTCTCAAGTACTCCTACGA
GAACCAAGTGTTCTCCATTACAAATGCCTCACTTAACGACACTGGCAGCTATCTCTGTAAGGGC
CGACTTCAGAAGCTGCCCTGTGTCTCTGAGCCCCTTCAAATTACAGTAATAACAGCATACCAAA
CCAAGTATATGTGGCTACAAATTATTGTCCCCTTGTTGGTGGCGACTCTGTTTGCTGTGGACAC
AGGACTGTTTTTCTTGACGGAGCAGCAGTTTAAACCTCTCTTGAAGATTAAGGAAACTGAAAAA
GTCAACAAACCTAGGAAGTCGCTTCCTAAGCCAGAGCCTGAAAAGAGCTGATGTCACTTCTTAA
GGGAGAATTGGCAACAGCAATATTTTACTGCACCAGCAATTGCTTCTCCATGGTCAGACACAAC
TCAAGATGTACATAGAAGCCTATGTTTGAGGATTTGCAGAATTATCTCATTAAACCAACTGTAC
CTGG

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Protein Sequences


Protein RefSeqs	XP_005339475	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_005339475 ⟸ XM_005339418

- Sequence:

show sequence

MDVDLIPTPRSQYCGVPEDWGEMLTSPFWTFAALAGTLTGNRKSILTLNPPWNRIFRGENVTLE
CKGNNFTEDSHTVWTHNGTISEVTTSKWSIVNATYQHSGKYTCHGRNFYKSKPVYLEVISDWML
LQASAEQVLEGESLFLRCHGWRNWKIRKVIYYKNDMALKYSYENQVFSITNASLNDTGSYLCKG
RLQKLPCVSEPLQITVITAYQTKYMWLQIIVPLLVATLFAVDTGLFFLTEQQFKPLLKIKETEK
VNKPRKSLPKPEPEKS

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Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Fcer1a	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - SMPDB