Thy1 (Thy-1 cell surface antigen)

Gene: Thy1 (Thy-1 cell surface antigen) Ictidomys tridecemlineatus

Analyze

Symbol:

Thy1

Name:

Thy-1 cell surface antigen

RGD ID:

12615701

Description:

ENCODES a protein that exhibits enzyme binding (ortholog); GPI anchor binding (ortholog); protein kinase binding (ortholog); INVOLVED IN cell-cell signaling (ortholog); cytoskeleton organization (ortholog); focal adhesion assembly (ortholog); PARTICIPATES IN interleukin-4 signaling pathway; ASSOCIATED WITH CD3epsilon deficiency (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); Dwarfism (ortholog); FOUND IN axolemma (ortholog); cell surface (ortholog); cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

thy-1 membrane glycoprotein

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	101,402,496 - 101,408,588 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936542	4,323,408 - 4,330,077 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936542	4,323,905 - 4,329,940 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

CD3epsilon deficiency (ISO)

Chromosome 11, Partial Trisomy 11q (ISO)

Dwarfism (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

immunodeficiency 17 (ISO)

immunodeficiency 18 (ISO)

immunodeficiency 19 (ISO)

inflammatory bowel disease 28 (ISO)

isolated microphthalmia 5 (ISO)

RASopathy (ISO)

Reperfusion Injury (ISO)

retinal disease (ISO)

retinal ischemia (ISO)

schizophrenia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (IEA)

cell adhesion (IEA)

cell-cell adhesion (IEA)

cell-cell signaling (IEA,ISO)

cytoskeleton organization (ISO)

focal adhesion assembly (ISO)

heterotypic cell-cell adhesion (IEA)

integrin-mediated signaling pathway (IEA)

negative regulation of axonogenesis (ISO)

negative regulation of cell migration (ISO)

negative regulation of neuron projection regeneration (IEA,ISO)

negative regulation of T cell receptor signaling pathway (IEA)

positive regulation of cellular extravasation (IEA)

positive regulation of focal adhesion assembly (IEA)

positive regulation of release of sequestered calcium ion into cytosol (ISO)

positive regulation of T cell activation (ISO)

receptor clustering (ISO)

regulation of cell migration (IEA)

regulation of cell-matrix adhesion (IEA)

response to axon injury (ISO)

retinal cone cell development (IEA)

T cell receptor signaling pathway (IEA)

Cellular Component

apical plasma membrane (IEA)

axolemma (ISO)

cell surface (IEA,ISO)

cytosol (ISO)

dendrite (IEA)

dendrite membrane (ISO)

endoplasmic reticulum (IEA)

external side of plasma membrane (IEA)

focal adhesion (IEA)

glutamatergic synapse (ISO)

growth cone (ISO)

membrane (IEA)

membrane raft (IEA)

myelin sheath (IEA)

neuronal cell body membrane (ISO)

plasma membrane (IEA)

postsynapse (ISO)

presynapse (ISO)

Molecular Function

enzyme binding (ISO)

GPI anchor binding (ISO)

GTPase activator activity (IEA)

integrin binding (IEA)

protein binding (ISO)

protein kinase binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

interleukin-4 signaling pathway (ISO)

References

Genomics

Comparative Map Data

Thy1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	101,402,496 - 101,408,588 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936542	4,323,408 - 4,330,077 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936542	4,323,905 - 4,329,940 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

THY1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	119,415,476 - 119,424,985 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	119,415,476 - 119,424,985 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	119,286,186 - 119,295,695 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	118,794,098 - 118,799,064 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	118,794,097 - 118,799,064	NCBI
Celera	11	116,449,333 - 116,454,924 (-)	NCBI		Celera
Cytogenetic Map	11	q23.3	NCBI
HuRef	11	115,230,310 - 115,235,710 (-)	NCBI		HuRef
CHM1_1	11	119,175,213 - 119,180,804 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	119,437,019 - 119,446,528 (-)	NCBI		T2T-CHM13v2.0

Thy1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	43,954,681 - 43,959,876 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	43,954,681 - 43,959,876 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	44,043,384 - 44,048,579 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	44,043,384 - 44,048,579 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	43,851,467 - 43,856,662 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	43,796,949 - 43,799,573 (+)	NCBI		MGSCv36	mm8
Celera	9	41,300,956 - 41,306,126 (+)	NCBI		Celera
Cytogenetic Map	9	A5.1	NCBI
cM Map	9	24.52	NCBI

Thy1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	53,286,396 - 53,291,541 (+)	NCBI		GRCr8
mRatBN7.2	8	44,389,495 - 44,394,688 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	44,389,513 - 44,394,659 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	49,887,923 - 49,892,732 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	48,166,622 - 48,171,433 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	46,034,211 - 46,039,022 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	48,382,121 - 48,387,271 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	48,382,121 - 48,386,935 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	46,998,623 - 47,003,773 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	47,027,721 - 47,031,857 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	47,036,486 - 47,040,623 (+)	NCBI
Celera	8	43,976,742 - 43,981,520 (+)	NCBI		Celera
RH 3.4 Map	2	1191.8	RGD
Cytogenetic Map	8	q22	NCBI

Thy1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	20,480,284 - 20,484,958 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	20,480,284 - 20,484,958 (-)	NCBI	ChiLan1.0	ChiLan1.0

THY1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	120,120,258 - 120,125,745 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	121,223,735 - 121,228,812 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	114,253,535 - 114,259,495 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	118,180,717 - 118,186,901 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	118,180,717 - 118,186,901 (-)	Ensembl	panpan1.1		panPan2

THY1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	14,503,902 - 14,509,113 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	14,503,902 - 14,509,113 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	14,557,503 - 14,562,714 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	14,447,441 - 14,452,656 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	14,447,423 - 14,452,742 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	14,585,674 - 14,590,877 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	14,489,710 - 14,494,914 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	14,529,873 - 14,535,084 (+)	NCBI		UU_Cfam_GSD_1.0

THY1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	46,607,494 - 46,612,269 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	46,607,022 - 46,612,691 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	51,639,467 - 51,644,315 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

THY1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	110,787,213 - 110,791,536 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	110,783,877 - 110,791,569 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	15,243,058 - 15,247,526 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Thy1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624784	14,780,698 - 14,784,897 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624784	14,779,533 - 14,784,315 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005328377	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040285373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000005437 ⟹ ENSSTOP00000004865

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936542	4,323,408 - 4,330,077 (-)	Ensembl

RefSeq Acc Id:

XM_005328377 ⟹ XP_005328434

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	101,402,496 - 101,408,588 (-)	NCBI
SpeTri2.0	NW_004936542	4,323,905 - 4,329,940 (-)	NCBI

Sequence:

show sequence

AACTGCGGGCTCTTTGCAGGGTGCAGCAACTGGAGGCGGCGGTGCATCCAGAGGAGGCTGCTGC
AGCAGAGCAACAGAGCGCAGGACTGAGCTCGTGGCACCATGAACCCGGCCATCGGCATCGCTGT
CCTGCTGGCAGTCTTACAGGTATCCCGAGGGCAGAAGGTGACCAGCCTAACGGCCTGCCTGGTG
AACCAGAGCCTCCGTCTGGACTGCCACCATGAGAATACCACCACCTCGCCCATCCAGTACGAAT
TCAGCCTGACCCGTGAGAAAAAGAAGCACGTGCTCTTTGGCACCGTGGGGGTACCCGAGCACTC
ATACCGCTCCCGGACCAACTTCACCAGCAAGTACAACATGAAGGTCCTCTACTTAGCCGACTTT
ACCAACAAGGATGAGGGGATCTACTCGTGCGAACTCCGCCTCTCCGGTCAGCCTCAAAGCATGC
CCCAGTCACAGAATATCTCTGTGCTCAGAGACAAGCTGGTCAAGTGTGAGGGCATAAGCCTGCT
GGCTCAGAATACCTCATGGCTGCTGCTGCTCCTGCTCTCACTCTCCCTCCTCCAGGCCACGGAT
TTCATTTCCCTGTGACTGGTTGGGCCCACGGAGGACACAGGAAGCCTCAAGGCCTGTGCAGAGA
AGGTCCTGCTTCTCTGAGTTGGCTGACCCTCTCCTCCCAGTCCCTCTCACACCTTGGGGAAACA
TGGGGACCCCACCCCTTGTAAGGAATCCCAGTGCTGCATGCCATCATCCACCCACCTAACCCAC
TGCCACTTCACCCTCTCCGCACGCCACTGGCTGTCTTTTTGTACTCTTTGTTCCAGAGCTGCTT
CTGTCTGGTTTATTTAGGGTTTATCCTTCCTTTTCTTTGGGAGTTTGTGACAAGGGAAGCCAGG
GTAGGAGACCTGGTGGAGAGTGAGGTCATGTGACCAGTAGAGGGTACCAGTCTCTGGGTGAGTC
TATCCACACCCACCAGAACCACAGGCCTGGGAGAGACCTGGACAGGGAGGAGGTGAGGTATGTC
TGGGTCTGGCACCTCAAGACCCCGATGTGAGGGCACCACCCAGCATGTGTAGCCATGGCGTGAG
GGTGAGAACTGAGCGTCTCCAGGAACATTCTCGGGCACAGCAAATAAGCCACCCTCTTGCCACA
GCAGAAGTCTCCTAGGGACATTGGGCCAGAGGCCTGATCCAGTGGAGATGCAGAGTCGGCCAGG
AAGCAGCAGCACAAAATGGAGGGGTGGAGAAGCGGGTGGGAGGTAAGGGCACATCACCCCTCCA
CAGTGAAAGACGCTGAAATGTGAGGCTGCTGTCCCTCACTGCTGCAGCCTGCAGTTGTGAGGGT
GGCAGAGGAGGACAAACCCCTTCCTGGATTGTCCCAAGCTCCTAAGAGCTTCCAGATCACTAAC
CTGCAGGCTCTGCAAGGAAGAAGGAGAGAGTCCCAGAGCCACACAGCTTGGCCCAAGTTCCTAA
AGGAGGCTCTTCTTTCCCTTGCCCATAAGTGCCAGCCCCTGCTGGCTGGGCCTTGAGCCCCCAG
ACAGCCCCTGCCCCACAGACTTGCCTCCTCCGGAACCGAGGGGGGCCCAAGGCAGGCCATGGAG
TGAGACCCTGAAGTTGCACACTCCTTGGGAGATGGCTTTTCCCAACACCCAGCTCCCCACCCGG
CAGCTCTGCCTGTCCCGTGACTGTGTATAGTGCCACAGCTTAATGGCATCTCATTGAGGAAAAA
GCAAACTGCACAATAAAACCAAGCCTCTGGAGTCTG

hide sequence

RefSeq Acc Id:

XM_040285373 ⟹ XP_040141307

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	101,402,496 - 101,408,197 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005328434	(Get FASTA)	NCBI Sequence Viewer
	XP_040141307	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000004865.2
GenBank Protein	KAG3286735	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005328434 ⟸ XM_005328377
- UniProtKB:	I3M627 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNPAIGIAVLLAVLQVSRGQKVTSLTACLVNQSLRLDCHHENTTTSPIQYEFSLTREKKKHVLF GTVGVPEHSYRSRTNFTSKYNMKVLYLADFTNKDEGIYSCELRLSGQPQSMPQSQNISVLRDKL VKCEGISLLAQNTSWLLLLLLSLSLLQATDFISL hide sequence

RefSeq Acc Id:	XP_040141307 ⟸ XM_040285373
- UniProtKB:	I3M627 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000004865 ⟸ ENSSTOT00000005437

Protein Domains

Ig-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000005455	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000005437.3	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	Ig-like_dom	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/TrEMBL
	Immunoglobulin	UniProtKB/TrEMBL
	THY1	UniProtKB/TrEMBL
NCBI Gene	Thy1	ENTREZGENE
PANTHER	PTHR19226	UniProtKB/TrEMBL
	THY-1 MEMBRANE GLYCOPROTEIN	UniProtKB/TrEMBL
Pfam	PF00047	UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/TrEMBL
SMART	IGv	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
UniProt	I3M627	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)