Mbd2 (methyl-CpG binding domain protein 2) - Rat Genome Database

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Gene: Mbd2 (methyl-CpG binding domain protein 2) Ictidomys tridecemlineatus
Analyze
Symbol: Mbd2
Name: methyl-CpG binding domain protein 2
RGD ID: 12613956
Description: ENCODES a protein that exhibits chromatin binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to organic cyclic compound (ortholog); embryonic organ development (ortholog); epigenetic regulation of gene expression (ortholog); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; DNA modification pathway; ASSOCIATED WITH Brain Hypoxia-Ischemia (ortholog); choline deficiency disease (ortholog); Familial Prostate Cancer (ortholog); FOUND IN chromatin (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: methyl-CpG-binding domain protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494434,305,611 - 34,380,215 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364979,545,907 - 9,619,267 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364979,512,350 - 9,619,250 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Mbd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494434,305,611 - 34,380,215 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364979,545,907 - 9,619,267 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364979,512,350 - 9,619,250 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MBD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381854,151,606 - 54,224,669 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1854,151,606 - 54,224,669 (-)EnsemblGRCh38hg38GRCh38
GRCh371851,677,976 - 51,751,039 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361849,934,573 - 50,005,156 (-)NCBINCBI36Build 36hg18NCBI36
Build 341849,983,044 - 50,005,156NCBI
Celera1848,536,865 - 48,607,453 (-)NCBICelera
Cytogenetic Map18q21.2NCBI
HuRef1848,533,225 - 48,606,305 (-)NCBIHuRef
CHM1_11851,672,993 - 51,746,130 (-)NCBICHM1_1
T2T-CHM13v2.01854,354,681 - 54,427,744 (-)NCBIT2T-CHM13v2.0
Mbd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391870,701,298 - 70,761,769 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1870,701,260 - 70,759,202 (+)EnsemblGRCm39 Ensembl
GRCm381870,568,225 - 70,629,134 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1870,568,189 - 70,626,131 (+)EnsemblGRCm38mm10GRCm38
MGSCv371870,727,946 - 70,785,785 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361870,693,557 - 70,751,499 (+)NCBIMGSCv36mm8
Celera1871,855,127 - 71,913,052 (+)NCBICelera
Cytogenetic Map18E2NCBI
cM Map1844.54NCBI
Mbd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81866,449,196 - 66,516,112 (+)NCBIGRCr8
mRatBN7.21864,174,002 - 64,240,795 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1864,174,002 - 64,240,794 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1866,250,441 - 66,317,290 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01866,943,914 - 67,010,763 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01864,791,202 - 64,858,194 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01865,814,026 - 65,885,115 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1865,814,026 - 65,885,114 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01864,990,480 - 65,060,941 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41867,281,440 - 67,348,558 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11867,378,120 - 67,421,847 (+)NCBI
Celera1862,237,373 - 62,304,615 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Mbd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540238,767,419 - 38,830,204 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540238,761,668 - 38,829,830 (-)NCBIChiLan1.0ChiLan1.0
MBD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21771,682,971 - 71,755,813 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11857,372,347 - 57,448,428 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01847,534,356 - 47,609,481 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11850,876,490 - 50,946,077 (-)NCBIpanpan1.1PanPan1.1panPan2
MBD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,232,260 - 21,283,687 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,235,967 - 21,283,346 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,214,129 - 22,277,156 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,116,138 - 21,179,161 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,116,177 - 21,179,029 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,172,397 - 21,235,448 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,064,613 - 21,127,587 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,336,222 - 21,399,248 (+)NCBIUU_Cfam_GSD_1.0
MBD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1103,735,192 - 103,752,402 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11103,683,077 - 103,768,372 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21113,947,945 - 113,959,372 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MBD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11826,714,610 - 26,785,028 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666050632,587 - 703,065 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mbd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477817,883,933 - 17,959,880 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477817,880,480 - 17,959,879 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000011249   ⟹   ENSSTOP00000010090
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364979,545,907 - 9,619,267 (+)Ensembl
RefSeq Acc Id: XM_040270252   ⟹   XP_040126186
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494434,305,611 - 34,380,215 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040126186 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000010090.3
GenBank Protein KAG3293864 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040126186   ⟸   XM_040270252
RefSeq Acc Id: ENSSTOP00000010090   ⟸   ENSSTOT00000011249
Protein Domains
MBD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000011253 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000011249.3 UniProtKB/TrEMBL
InterPro DNA-bd_dom_sf UniProtKB/TrEMBL
  MBD2/MBD3_p55-bd UniProtKB/TrEMBL
  MeCpG-bd_2/3_C_dom UniProtKB/TrEMBL
  Methyl_CpG_DNA-bd UniProtKB/TrEMBL
NCBI Gene Mbd2 ENTREZGENE
PANTHER METHYL-CPG BINDING PROTEIN, MBD UniProtKB/TrEMBL
  METHYL-CPG-BINDING DOMAIN PROTEIN 2 UniProtKB/TrEMBL
Pfam MBD UniProtKB/TrEMBL
  MBD_C UniProtKB/TrEMBL
  MBDa UniProtKB/TrEMBL
PROSITE MBD UniProtKB/TrEMBL
SMART MBD UniProtKB/TrEMBL
Superfamily-SCOP SSF54171 UniProtKB/TrEMBL
UniProt I3MGY7_ICTTR UniProtKB/TrEMBL