Chrnb1 (cholinergic receptor nicotinic beta 1 subunit) - Rat Genome Database

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Gene: Chrnb1 (cholinergic receptor nicotinic beta 1 subunit) Ictidomys tridecemlineatus
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Symbol: Chrnb1
Name: cholinergic receptor nicotinic beta 1 subunit
RGD ID: 12612690
Description: ENCODES a protein that exhibits acetylcholine receptor activity (ortholog); acetylcholine-gated monoatomic cation-selective channel activity (ortholog); ligand-gated monoatomic ion channel activity (ortholog); INVOLVED IN monoatomic cation transport (ortholog); regulation of membrane potential (ortholog); skeletal muscle contraction (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH common variable immunodeficiency (ortholog); congenital myasthenic syndrome (ortholog); congenital myasthenic syndrome 2A (ortholog); FOUND IN acetylcholine-gated channel complex (ortholog); neuromuscular junction (ortholog); postsynaptic specialization membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acetylcholine receptor subunit beta; cholinergic receptor nicotinic beta 1 subunit, transcript variant X1; cholinergic receptor nicotinic beta 1 subunit, transcript variant X2; cholinergic receptor nicotinic beta 1 subunit, transcript variant X3; cholinergic receptor nicotinic beta 1 subunit, transcript variant X4; cholinergic receptor nicotinic beta 1 subunit, transcript variant X5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,253,704 - 47,261,819 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936595727,980 - 735,783 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936595727,907 - 735,783 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Chrnb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,253,704 - 47,261,819 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936595727,980 - 735,783 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936595727,907 - 735,783 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHRNB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,445,061 - 7,457,710 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,445,061 - 7,457,710 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,348,380 - 7,361,029 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,289,130 - 7,301,656 (+)NCBINCBI36Build 36hg18NCBI36
Build 34177,289,129 - 7,301,656NCBI
Celera177,374,294 - 7,386,883 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,242,351 - 7,254,625 (+)NCBIHuRef
CHM1_1177,357,504 - 7,370,035 (+)NCBICHM1_1
T2T-CHM13v2.0177,349,120 - 7,361,750 (+)NCBIT2T-CHM13v2.0
Chrnb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,674,862 - 69,686,742 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,674,862 - 69,686,769 (-)EnsemblGRCm39 Ensembl
GRCm381169,784,036 - 69,795,966 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,784,036 - 69,795,943 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,597,538 - 69,609,439 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,600,232 - 69,612,138 (-)NCBIMGSCv36mm8
MGSCv361170,368,144 - 70,380,050 (-)NCBIMGSCv36mm8
Cytogenetic Map11B3NCBI
cM Map1142.87NCBI
Chrnb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,999,943 - 55,015,137 (-)NCBIGRCr8
mRatBN7.21054,501,096 - 54,516,418 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,501,093 - 54,516,345 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,166,354 - 59,178,879 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,654,919 - 58,667,445 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,162,545 - 54,175,096 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,390,671 - 56,403,255 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,390,671 - 56,403,188 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,135,720 - 56,148,237 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,604,907 - 56,617,423 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11056,618,529 - 56,631,046 (-)NCBI
Celera1053,658,103 - 53,670,628 (-)NCBICelera
Cytogenetic Map10q24NCBI
Chrnb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,471,962 - 9,482,370 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554679,471,962 - 9,482,370 (-)NCBIChiLan1.0ChiLan1.0
CHRNB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21915,041,812 - 15,053,022 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11717,007,603 - 17,018,838 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,479,056 - 7,490,314 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,465,229 - 7,476,099 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,465,229 - 7,476,099 (+)Ensemblpanpan1.1panPan2
CHRNB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,375,152 - 32,383,517 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,375,215 - 32,382,929 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,513,277 - 32,521,649 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,480,862 - 32,489,239 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,480,903 - 32,489,017 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,446,084 - 32,454,448 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,404,809 - 32,413,162 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,582,085 - 32,590,461 (+)NCBIUU_Cfam_GSD_1.0
CHRNB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,749,473 - 52,758,488 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,749,422 - 52,774,642 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21254,977,614 - 55,002,976 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHRNB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,821,842 - 6,832,758 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl166,822,065 - 6,833,768 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,575,541 - 14,586,609 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chrnb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478610,056,478 - 10,065,735 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478610,056,458 - 10,065,768 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Sequence


Ensembl Acc Id: ENSSTOT00000000340   ⟹   ENSSTOP00000000304
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936595727,980 - 735,783 (+)Ensembl
RefSeq Acc Id: XM_005332796   ⟹   XP_005332853
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,253,704 - 47,261,819 (+)NCBI
SpeTri2.0NW_004936595727,907 - 735,783 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040269362   ⟹   XP_040125296
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,254,298 - 47,261,819 (+)NCBI
RefSeq Acc Id: XP_005332853   ⟸   XM_005332796
- Peptide Label: isoform X1
- UniProtKB: I3LWF2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040125296   ⟸   XM_040269362
- Peptide Label: isoform X2
Ensembl Acc Id: ENSSTOP00000000304   ⟸   ENSSTOT00000000340

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000341 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000340.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.390 UniProtKB/TrEMBL
  2.70.170.10 UniProtKB/TrEMBL
InterPro Neur_chan_lig-bd UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/TrEMBL
  Neur_channel UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/TrEMBL
  Nicotinic_acetylcholine_rcpt UniProtKB/TrEMBL
NCBI Gene Chrnb1 ENTREZGENE
PANTHER ACETYLCHOLINE RECEPTOR SUBUNIT BETA UniProtKB/TrEMBL
  PTHR18945 UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/TrEMBL
PRINTS NICOTINICR UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF63712 UniProtKB/TrEMBL
  SSF90112 UniProtKB/TrEMBL
UniProt I3LWF2 ENTREZGENE, UniProtKB/TrEMBL