Nars1 (asparaginyl-tRNA synthetase 1)

Gene: Nars1 (asparaginyl-tRNA synthetase 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Nars1

Name:

asparaginyl-tRNA synthetase 1

RGD ID:

12612250

Description:

ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); asparagine-tRNA ligase activity (inferred); ATP binding (inferred); INVOLVED IN asparaginyl-tRNA aminoacylation (inferred); cell migration (inferred); cerebral cortex development (inferred); PARTICIPATES IN Canavan disease pathway; ASSOCIATED WITH Developmental Disease (ortholog); genetic disease (ortholog); immunodeficiency 12 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

asparagine--tRNA ligase, cytoplasmic; asparaginyl-tRNA synthetase; asparaginyl-tRNA synthetase, transcript variant X1; asparaginyl-tRNA synthetase, transcript variant X2; Nars

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	31,488,718 - 31,506,297 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936497	6,727,676 - 6,745,417 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936497	6,727,676 - 6,745,187 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Developmental Disease (ISO)

genetic disease (ISO)

immunodeficiency 12 (ISO)

isolated microphthalmia 3 (ISO)

Neurodevelopmental Disorder with Microcephaly, Impaired Language, and Gait Abnormalities (ISO)

Neurodevelopmental Disorder with Microcephaly, Impaired Language, Epilepsy, and Gait Abnormalities (ISO)

Neurodevelopmental Disorders (ISO)

nuclear type mitochondrial complex I deficiency 35 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

asparaginyl-tRNA aminoacylation (IEA)

cell migration (IEA)

cerebral cortex development (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

Molecular Function

aminoacyl-tRNA ligase activity (IEA)

asparagine-tRNA ligase activity (IEA)

ATP binding (IEA)

CCR3 chemokine receptor binding (IEA)

nucleic acid binding (IEA)

protein binding (ISO)

protein dimerization activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

Canavan disease pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Nars1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	31,488,718 - 31,506,297 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936497	6,727,676 - 6,745,417 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936497	6,727,676 - 6,745,187 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NARS1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	57,600,656 - 57,621,836 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	57,600,656 - 57,622,213 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	55,267,888 - 55,289,068 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	53,418,889 - 53,440,175 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	18	53,418,893 - 53,440,011	NCBI
Celera	18	51,984,720 - 52,006,007 (-)	NCBI		Celera
Cytogenetic Map	18	q21.31	NCBI
HuRef	18	51,978,101 - 51,999,377 (-)	NCBI		HuRef
CHM1_1	18	55,263,118 - 55,284,404 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	18	57,801,009 - 57,822,190 (-)	NCBI		T2T-CHM13v2.0

Nars1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	64,632,726 - 64,649,586 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	64,632,718 - 64,649,723 (-)	Ensembl		GRCm39 Ensembl
GRCm38	18	64,499,655 - 64,516,515 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	64,499,647 - 64,516,652 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	64,659,301 - 64,676,211 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	64,625,027 - 64,641,906 (-)	NCBI		MGSCv36	mm8
Celera	18	65,766,039 - 65,782,941 (-)	NCBI		Celera
Cytogenetic Map	18	E1	NCBI
cM Map	18	37.47	NCBI

Nars1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	60,259,506 - 60,275,782 (-)	NCBI		GRCr8
mRatBN7.2	18	57,989,308 - 58,005,584 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	57,989,308 - 58,005,622 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	60,071,361 - 60,087,924 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	60,783,120 - 60,799,457 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	58,613,019 - 58,629,294 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	59,986,350 - 60,002,644 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	59,986,360 - 60,002,569 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	59,196,509 - 59,212,779 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	60,719,399 - 60,736,058 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	60,792,599 - 60,809,219 (-)	NCBI
Celera	18	56,126,436 - 56,142,652 (-)	NCBI		Celera
Cytogenetic Map	18	q12.1	NCBI

Nars1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	41,946,098 - 41,967,644 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	41,947,592 - 41,967,136 (-)	NCBI	ChiLan1.0	ChiLan1.0

NARS1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	75,140,709 - 75,161,623 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	60,833,321 - 60,854,234 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	50,991,047 - 51,011,628 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	54,326,053 - 54,346,454 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	54,326,053 - 54,346,454 (-)	Ensembl	panpan1.1		panPan2

NARS1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	18,320,941 - 18,338,185 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	18,321,021 - 18,337,430 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	19,304,396 - 19,321,648 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	18,201,902 - 18,219,139 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	18,201,978 - 18,239,035 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	18,258,533 - 18,275,798 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	18,156,275 - 18,173,532 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	18,425,195 - 18,442,461 (+)	NCBI		UU_Cfam_GSD_1.0

NARS1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	106,911,277 - 106,933,118 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	106,911,267 - 106,933,105 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	117,493,562 - 117,510,483 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NARS1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	22,107,287 - 22,129,378 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	22,107,291 - 22,131,140 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666060	3,438,660 - 3,461,189 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nars1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624792	3,109,779 - 3,128,957 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624792	3,109,779 - 3,128,949 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005323035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005323036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000002122 ⟹ ENSSTOP00000001891

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936497	6,728,805 - 6,744,175 (+)	Ensembl

RefSeq Acc Id:

ENSSTOT00000036322 ⟹ ENSSTOP00000031130

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936497	6,727,676 - 6,745,417 (+)	Ensembl

RefSeq Acc Id:

XM_005323035 ⟹ XP_005323092

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404944	31,488,718 - 31,506,297 (+)	NCBI
SpeTri2.0	NW_004936497	6,727,676 - 6,745,187 (+)	NCBI

Sequence:

show sequence

CCGGAAGTTATCTCTGCCCTGACAAAAGATGGCGGCCGTGGCGTCTCTCGCCCACCTGCCGTAG
CCAATGGAACCCCGACGCTCGACTGACTCACACCTGCGACCTGCGGCACTACGTTGCATGATGC
AACCCTGGAGTCAAGGAAGCTTTTCCCGCACGTTGGGGTGACTGGGCGGTGGCGGTGTTGGGAC
CATGTCCTTGGAAGTGACCAGGGCGACTGCAGGGATGGTGCTAGCAGAGCTGTATGTCTCAGAT
CGAGAGGGAAATGATGCCACCGGAGATGGAACCAAAGAGAAGCCATTTAAAACAGGCCTAAAGG
CTTTGATGACAGTAGGAAAAGAACCATTTCCTACCATTTATGTAGATTCACAAAAAGAAAATGA
GAGGTGGGACATTATTTCTAAATCACAGATGAAGAACATTAGGAAAATGTGGCATAGGGAACAA
ATGAAGAGTGAATCCCGAGAGAAGAAAGAGGCAGAAGATAATTTGCGAAGAGAAAAGAACCTCG
AAGAAGCAAAGAAGATTACCATTAAAAATGATCCAAGTCTGCCAGAGCCACAGTGTGTGAAGAT
TCATGCATTAGAAGGATATAGAGGCCAGAGAGTGAAGGTTTTTGGCTGGGTCCATAGGCTGCGT
AGGCAAGGAAAGAATTTAATGTTCCTGGTGTTGCGGGATGGTACGGGTTATCTTCAGTGTGTCT
TGTCGGATGAGTTGTGTCAGTGTTATAATGGAGTAGTTTTGTCTACTGAGAGTAGTGTTGCTGT
ATATGGAATGCTAAATCTTACTCCAAAGGGCAAACAGGCTCCAGGGGGCCACGAGCTGAGTTGT
GACTTCTGGGAACTTATGGGGTTAGCCCCTGCTGGAGGAGCAGATAACTTAATCAATGAAGAAT
CTGATGTTGATGTCCAGCTGAACAATAGGCATATGATGATCCGAGGAGAAAATATGTCCAAAAT
CCTAAAAGCACGTTCCATGATCACCAGATGCTTCAGAGATCACTTCTTTGATAGGGGTTACTGT
GAAGTTACTCCTCCAACGTTGGTGCAGACGCAGGTAGAAGGTGGTGCCACGCTCTTCAAGCTTG
ACTATTTCGGGGAAGAGGCATTTTTGACTCAGTCCTCTCAGTTGTACCTGGAGACCTGCCTTCC
ATCCTTGGGAGATGTTTTTTGTATTGCACAGTCATACAGAGCAGAACAATCCAGAACACGAAGG
CACCTGGCTGAGTACACTCACGTGGAAGCTGAGTGCCCTTTCCTGACCTTTGAGGATCTCCTGA
ACAGATTGGAGGACTTGGTTTGTGATGTGGTAGATAGAGTCTTAAAATCACCGGCAGCAAGCAT
AGTGTATGACCTCAACCCGAACTTTAAACCCCCTAAACGGCCTTTCAAACGGATGAACTACTCA
GATGCTATTGTGTGGCTAAAAGAACACAATGTAAAGAAAGAAGATGGGACTTTCTATGAATTTG
GAGAAGATATCCCAGAAGCTCCTGAGAGACTAATGACAGACACCATTAATGAACCAATCTTGCT
GTGTCGATTTCCTGTGGAGATCAAGTCCTTCTACATGCAGCGATGTCCTGAGGATTCCCGCCTT
ACTGAATCTGTTGACGTGTTGATGCCCAATGTTGGTGAGATTGTGGGAGGCTCAATGCGTATCT
GGGATAGTGAAGAAATTCTGGCAGGTTATAAAAGGGAAGGGATTGACCCCACTCCTTATTACTG
GTATACAGATCAGAGGAAATATGGTACATGTCCTCATGGAGGATACGGCTTGGGCTTAGAACGA
TTCCTGACTTGGATTCTGAATAGATATCACATCCGAGATGTATGCTTGTACCCTCGATTTGTCC
AGCGCTGTAAGCCATAACTGATTCCTCCTAAAGCATGAAGAAAAGATGGTCATGAAAGGAACAG
ACTGCCTCATTAAAAAAGGAACAAAATGCCAAATTGTCCCATGTTTATTCCATTGGGGTACAGC
TTTCTGTTTTTTATTCCCAGCTACCATAAAACCATAAAAAGTAGTTCACATTATTTGAATATCA
GGGGACATTGATATCATTTTAAGAAAAAATATCCACTACAAAGTCTGGGGAAAATATGTGGCAT
GTAACTGTAGTTATGGATACATTTCGGAATTTTATCCAGTTATAGCAATTGTGTTAAATATGCC
ATCCATAATTAGTTTTTAATTATCATGTAAGGTATCCTAAAAAATATATTTAAAGCTTAAACTT
TCTGTACTTTTAAATGTAACTGGAATTCTTTAATTTGTATCATTTTATTGTATCAGTGATTTAA
AACACATCTGTGGGGGCAGTTCACAGTGTGGGCATAAAGATTTGCTAGTGTTAGAGTGTACCTC
AGCAGTAGATTCTGGAATCTAATGAGTACATTGTTTTACATCAGTTAATCTTTTCTGAATCCAC
ATAGTTGCTTTTAATTTTGAGGCATATGATTTGATATGGAAGAATTTGTAAAAGTGGATTTGCC
TTAAAATTTAAAGTGAGCATAATTGTTGGGGAGAGGCGTGGTATTTAAATGATTGACAACATCC
TTCATAGCATTAGTTTAAGATAAAGGGGTAGACCGAGCTTCCTTCTTTCCTGGTGATTTTTAAA
ATTAAAAATATGTTCCAAAAGAATTTGGCAGTTTGAATCTTAACAAAACTGACTGGCTGGTTGA
GTCATCCCTCCCACGTCCTTAGAGCTGGTCTGTGCTACCTTACATACTTCATAGCAGGATTACT
GAATGGCTTCAGAGCAGATTTAGTTAATTTTTCCCTCAAATGCATGCCATGTATTCTCAATAGG
CTGTATTTTCCCAGTGATCAATAAATGGAACACTCATTAAAAACTCTTTGCTGGTTTAATGTTC
TCAAA

hide sequence

RefSeq Acc Id:

XM_005323036 ⟹ XP_005323093

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404944	31,488,723 - 31,506,297 (+)	NCBI
SpeTri2.0	NW_004936497	6,727,761 - 6,745,187 (+)	NCBI

Sequence:

show sequence

ACTGACTCACACCTGCGACCTGCGGCACTACGTTGCATGATGCAACCCTGGAGTCAAGGAAGCT
TTTCCCGCACGTTGGGGTGACTGGGCGGTGGCGGTGTTGGGACCATGTCCTTGGAAGTGACCAG
GGCGACTGCAGGGATGGTGCTAGAGCTGTATGTCTCAGATCGAGAGGGAAATGATGCCACCGGA
GATGGAACCAAAGAGAAGCCATTTAAAACAGGCCTAAAGGCTTTGATGACAGTAGGAAAAGAAC
CATTTCCTACCATTTATGTAGATTCACAAAAAGAAAATGAGAGGTGGGACATTATTTCTAAATC
ACAGATGAAGAACATTAGGAAAATGTGGCATAGGGAACAAATGAAGAGTGAATCCCGAGAGAAG
AAAGAGGCAGAAGATAATTTGCGAAGAGAAAAGAACCTCGAAGAAGCAAAGAAGATTACCATTA
AAAATGATCCAAGTCTGCCAGAGCCACAGTGTGTGAAGATTCATGCATTAGAAGGATATAGAGG
CCAGAGAGTGAAGGTTTTTGGCTGGGTCCATAGGCTGCGTAGGCAAGGAAAGAATTTAATGTTC
CTGGTGTTGCGGGATGGTACGGGTTATCTTCAGTGTGTCTTGTCGGATGAGTTGTGTCAGTGTT
ATAATGGAGTAGTTTTGTCTACTGAGAGTAGTGTTGCTGTATATGGAATGCTAAATCTTACTCC
AAAGGGCAAACAGGCTCCAGGGGGCCACGAGCTGAGTTGTGACTTCTGGGAACTTATGGGGTTA
GCCCCTGCTGGAGGAGCAGATAACTTAATCAATGAAGAATCTGATGTTGATGTCCAGCTGAACA
ATAGGCATATGATGATCCGAGGAGAAAATATGTCCAAAATCCTAAAAGCACGTTCCATGATCAC
CAGATGCTTCAGAGATCACTTCTTTGATAGGGGTTACTGTGAAGTTACTCCTCCAACGTTGGTG
CAGACGCAGGTAGAAGGTGGTGCCACGCTCTTCAAGCTTGACTATTTCGGGGAAGAGGCATTTT
TGACTCAGTCCTCTCAGTTGTACCTGGAGACCTGCCTTCCATCCTTGGGAGATGTTTTTTGTAT
TGCACAGTCATACAGAGCAGAACAATCCAGAACACGAAGGCACCTGGCTGAGTACACTCACGTG
GAAGCTGAGTGCCCTTTCCTGACCTTTGAGGATCTCCTGAACAGATTGGAGGACTTGGTTTGTG
ATGTGGTAGATAGAGTCTTAAAATCACCGGCAGCAAGCATAGTGTATGACCTCAACCCGAACTT
TAAACCCCCTAAACGGCCTTTCAAACGGATGAACTACTCAGATGCTATTGTGTGGCTAAAAGAA
CACAATGTAAAGAAAGAAGATGGGACTTTCTATGAATTTGGAGAAGATATCCCAGAAGCTCCTG
AGAGACTAATGACAGACACCATTAATGAACCAATCTTGCTGTGTCGATTTCCTGTGGAGATCAA
GTCCTTCTACATGCAGCGATGTCCTGAGGATTCCCGCCTTACTGAATCTGTTGACGTGTTGATG
CCCAATGTTGGTGAGATTGTGGGAGGCTCAATGCGTATCTGGGATAGTGAAGAAATTCTGGCAG
GTTATAAAAGGGAAGGGATTGACCCCACTCCTTATTACTGGTATACAGATCAGAGGAAATATGG
TACATGTCCTCATGGAGGATACGGCTTGGGCTTAGAACGATTCCTGACTTGGATTCTGAATAGA
TATCACATCCGAGATGTATGCTTGTACCCTCGATTTGTCCAGCGCTGTAAGCCATAACTGATTC
CTCCTAAAGCATGAAGAAAAGATGGTCATGAAAGGAACAGACTGCCTCATTAAAAAAGGAACAA
AATGCCAAATTGTCCCATGTTTATTCCATTGGGGTACAGCTTTCTGTTTTTTATTCCCAGCTAC
CATAAAACCATAAAAAGTAGTTCACATTATTTGAATATCAGGGGACATTGATATCATTTTAAGA
AAAAATATCCACTACAAAGTCTGGGGAAAATATGTGGCATGTAACTGTAGTTATGGATACATTT
CGGAATTTTATCCAGTTATAGCAATTGTGTTAAATATGCCATCCATAATTAGTTTTTAATTATC
ATGTAAGGTATCCTAAAAAATATATTTAAAGCTTAAACTTTCTGTACTTTTAAATGTAACTGGA
ATTCTTTAATTTGTATCATTTTATTGTATCAGTGATTTAAAACACATCTGTGGGGGCAGTTCAC
AGTGTGGGCATAAAGATTTGCTAGTGTTAGAGTGTACCTCAGCAGTAGATTCTGGAATCTAATG
AGTACATTGTTTTACATCAGTTAATCTTTTCTGAATCCACATAGTTGCTTTTAATTTTGAGGCA
TATGATTTGATATGGAAGAATTTGTAAAAGTGGATTTGCCTTAAAATTTAAAGTGAGCATAATT
GTTGGGGAGAGGCGTGGTATTTAAATGATTGACAACATCCTTCATAGCATTAGTTTAAGATAAA
GGGGTAGACCGAGCTTCCTTCTTTCCTGGTGATTTTTAAAATTAAAAATATGTTCCAAAAGAAT
TTGGCAGTTTGAATCTTAACAAAACTGACTGGCTGGTTGAGTCATCCCTCCCACGTCCTTAGAG
CTGGTCTGTGCTACCTTACATACTTCATAGCAGGATTACTGAATGGCTTCAGAGCAGATTTAGT
TAATTTTTCCCTCAAATGCATGCCATGTATTCTCAATAGGCTGTATTTTCCCAGTGATCAATAA
ATGGAACACTCATTAAAAACTCTTTGCTGGTTTAATGTTCTCAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005323092	(Get FASTA)	NCBI Sequence Viewer
	XP_005323093	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000001891.3
	ENSSTOP00000031130.1
GenBank Protein	KAG3293830	(Get FASTA)	NCBI Sequence Viewer
	KAG3293831	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005323092 ⟸ XM_005323035
- Peptide Label:	isoform X1
- UniProtKB:	A0A287DC26 (UniProtKB/TrEMBL), I3LZT6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSLEVTRATAGMVLAELYVSDREGNDATGDGTKEKPFKTGLKALMTVGKEPFPTIYVDSQKENE RWDIISKSQMKNIRKMWHREQMKSESREKKEAEDNLRREKNLEEAKKITIKNDPSLPEPQCVKI HALEGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLSDELCQCYNGVVLSTESSVAV YGMLNLTPKGKQAPGGHELSCDFWELMGLAPAGGADNLINEESDVDVQLNNRHMMIRGENMSKI LKARSMITRCFRDHFFDRGYCEVTPPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLP SLGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFEDLLNRLEDLVCDVVDRVLKSPAASI VYDLNPNFKPPKRPFKRMNYSDAIVWLKEHNVKKEDGTFYEFGEDIPEAPERLMTDTINEPILL CRFPVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIWDSEEILAGYKREGIDPTPYYW YTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYPRFVQRCKP hide sequence

RefSeq Acc Id:	XP_005323093 ⟸ XM_005323036
- Peptide Label:	isoform X2
- UniProtKB:	I3LZT6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSLEVTRATAGMVLELYVSDREGNDATGDGTKEKPFKTGLKALMTVGKEPFPTIYVDSQKENER WDIISKSQMKNIRKMWHREQMKSESREKKEAEDNLRREKNLEEAKKITIKNDPSLPEPQCVKIH ALEGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLSDELCQCYNGVVLSTESSVAVY GMLNLTPKGKQAPGGHELSCDFWELMGLAPAGGADNLINEESDVDVQLNNRHMMIRGENMSKIL KARSMITRCFRDHFFDRGYCEVTPPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPS LGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFEDLLNRLEDLVCDVVDRVLKSPAASIV YDLNPNFKPPKRPFKRMNYSDAIVWLKEHNVKKEDGTFYEFGEDIPEAPERLMTDTINEPILLC RFPVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIWDSEEILAGYKREGIDPTPYYWY TDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYPRFVQRCKP hide sequence

RefSeq Acc Id:

ENSSTOP00000001891 ⟸ ENSSTOT00000002122

RefSeq Acc Id:

ENSSTOP00000031130 ⟸ ENSSTOT00000036322

Protein Domains

Aminoacyl-transfer RNA synthetases class-II family

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000002118	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000002122.3	UniProtKB/TrEMBL
	ENSSTOT00000036322.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.50.140	UniProtKB/TrEMBL
	asparaginyl-tRNA synthetase, N-terminal domain	UniProtKB/TrEMBL
InterPro	Aa-tRNA-synt_II	UniProtKB/TrEMBL
	aa-tRNA-synth_II	UniProtKB/TrEMBL
	aa-tRNA-synth_II/BPL/LPL	UniProtKB/TrEMBL
	Asn-tRNA-ligase	UniProtKB/TrEMBL
	AsnRS_N	UniProtKB/TrEMBL
	Asp/Asn-tRNA-synth_IIb	UniProtKB/TrEMBL
	NA-bd_OB-fold	UniProtKB/TrEMBL
	NA-bd_OB_tRNA	UniProtKB/TrEMBL
NCBI Gene	Nars	ENTREZGENE
PANTHER	ASPARAGINE--TRNA LIGASE, CYTOPLASMIC	UniProtKB/TrEMBL
	ASPARTYL/LYSYL-TRNA SYNTHETASE	UniProtKB/TrEMBL
Pfam	AsnRS_N	UniProtKB/TrEMBL
	tRNA-synt_2	UniProtKB/TrEMBL
	tRNA_anti-codon	UniProtKB/TrEMBL
PRINTS	TRNASYNTHASP	UniProtKB/TrEMBL
PROSITE	AA_TRNA_LIGASE_II	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50249	UniProtKB/TrEMBL
	SSF55681	UniProtKB/TrEMBL
UniProt	A0A287DC26	ENTREZGENE, UniProtKB/TrEMBL
	I3LZT6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-07-23	Nars1	asparaginyl-tRNA synthetase 1	Nars	asparaginyl-tRNA synthetase	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB