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Gene: App (amyloid beta precursor protein) Ictidomys tridecemlineatus
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Symbol: App
Name: amyloid beta precursor protein
RGD ID: 12612074
Description: ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); apolipoprotein binding (ortholog); chaperone binding (ortholog); INVOLVED IN activation of MAPK activity (ortholog); activation of MAPKKK activity (ortholog); adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN glypican signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Alzheimer's disease 1 (ortholog); Alzheimer's Disease, Early-Onset, with Cerebral Amyloid Angiopathy (ortholog); FOUND IN amyloid-beta complex (ortholog); apical part of cell (ortholog); astrocyte projection (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Orthologs:
Homo sapiens (human) : APP (amyloid beta precursor protein)  HGNC  Alliance
Mus musculus (house mouse) : App (amyloid beta (A4) precursor protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : App (amyloid beta precursor protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : App (amyloid beta precursor protein)
Pan paniscus (bonobo/pygmy chimpanzee) : APP (amyloid beta precursor protein)
Canis lupus familiaris (dog) : APP (amyloid beta precursor protein)
Sus scrofa (pig) : APP (amyloid beta precursor protein)
Chlorocebus sabaeus (African green monkey) : APP (amyloid beta precursor protein)
Heterocephalus glaber (naked mole-rat) : App (amyloid beta precursor protein)
more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366401,549,977 - 1,787,436 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on App
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12612074
Created: 2017-01-27
Species: Ictidomys tridecemlineatus
Last Modified: 2020-08-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.