Rrp8 (ribosomal RNA processing 8) - Rat Genome Database

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Gene: Rrp8 (ribosomal RNA processing 8) Ictidomys tridecemlineatus
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Symbol: Rrp8
Name: ribosomal RNA processing 8
RGD ID: 12611588
Description: ENCODES a protein that exhibits methylated histone binding (inferred); methyltransferase activity (inferred); INVOLVED IN regulation of G1 to G0 transition (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); neuronal ceroid lipofuscinosis (ortholog); FOUND IN nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ribosomal RNA processing 8, methyltransferase, homolog; ribosomal RNA processing 8, methyltransferase, homolog (yeast); ribosomal RNA-processing protein 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494756,013,586 - 56,018,997 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936842657,727 - 661,757 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936842656,508 - 661,894 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rrp8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494756,013,586 - 56,018,997 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936842657,727 - 661,757 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936842656,508 - 661,894 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RRP8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,595,072 - 6,603,616 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl116,595,072 - 6,603,616 (-)EnsemblGRCh38hg38GRCh38
GRCh37116,616,302 - 6,624,846 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,577,728 - 6,581,387 (-)NCBINCBI36Build 36hg18NCBI36
Celera116,740,219 - 6,743,878 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef116,280,081 - 6,283,817 (-)NCBIHuRef
CHM1_1116,620,046 - 6,623,782 (-)NCBICHM1_1
T2T-CHM13v2.0116,653,543 - 6,662,088 (-)NCBIT2T-CHM13v2.0
Rrp8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397105,380,937 - 105,386,592 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7105,380,937 - 105,386,592 (-)EnsemblGRCm39 Ensembl
GRCm387105,731,730 - 105,737,385 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7105,731,730 - 105,737,385 (-)EnsemblGRCm38mm10GRCm38
MGSCv377112,880,723 - 112,885,014 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367105,606,030 - 105,610,321 (-)NCBIMGSCv36mm8
Celera7106,003,509 - 106,007,800 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.97NCBI
Rrp8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81169,489,829 - 169,500,551 (-)NCBIGRCr8
mRatBN7.21160,081,092 - 160,088,709 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1160,084,295 - 160,089,331 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1168,107,178 - 168,111,204 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01175,293,176 - 175,297,202 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01168,194,934 - 168,198,960 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01170,574,670 - 170,578,693 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1170,574,349 - 170,579,616 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01177,580,522 - 177,584,545 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41163,477,028 - 163,481,051 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11163,572,506 - 163,576,528 (-)NCBI
Celera1158,016,713 - 158,020,738 (-)NCBICelera
Cytogenetic Map1q32NCBI
Rrp8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541422,311,038 - 22,316,144 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541422,311,038 - 22,316,144 (-)NCBIChiLan1.0ChiLan1.0
RRP8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v298,933,905 - 9,040,858 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1118,899,731 - 9,004,646 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0116,630,695 - 6,735,711 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1116,314,285 - 6,418,557 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl116,415,003 - 6,418,414 (-)Ensemblpanpan1.1panPan2
RRP8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12129,907,555 - 29,917,142 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2129,907,361 - 29,918,408 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2129,609,154 - 29,619,614 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02130,733,473 - 30,743,933 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2130,733,473 - 30,737,354 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12130,054,253 - 30,064,707 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02130,219,908 - 30,230,374 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02130,415,227 - 30,425,693 (-)NCBIUU_Cfam_GSD_1.0
RRP8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl93,152,209 - 3,162,540 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.193,152,162 - 3,169,380 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.293,810,391 - 3,814,833 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RRP8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1158,221,861 - 58,225,470 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl158,221,869 - 58,225,329 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038156,047,610 - 156,051,373 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rrp8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248178,092,664 - 8,096,358 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248178,089,320 - 8,096,447 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005341112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSTOT00000016274   ⟹   ENSSTOP00000014571
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936842657,727 - 661,757 (-)Ensembl
RefSeq Acc Id: XM_005341112   ⟹   XP_005341169
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494756,013,586 - 56,018,997 (+)NCBI
SpeTri2.0NW_004936842656,508 - 661,894 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005341169 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000014571.2
GenBank Protein KAG3285832 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005341169   ⟸   XM_005341112
- UniProtKB: I3MR87 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000014571   ⟸   ENSSTOT00000016274


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000016272 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000016274.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.2150 UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/TrEMBL
InterPro RRP8 UniProtKB/TrEMBL
  RRP8_N UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
  UbiE/COQ5_MeTrFase_CS UniProtKB/TrEMBL
NCBI Gene Rrp8 ENTREZGENE
PANTHER PTHR12787 UniProtKB/TrEMBL
  RIBOSOMAL RNA-PROCESSING PROTEIN 8 UniProtKB/TrEMBL
Pfam Methyltransf_8 UniProtKB/TrEMBL
PROSITE UBIE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt I3MR87 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-30 Rrp8  ribosomal RNA processing 8    ribosomal RNA processing 8, methyltransferase, homolog (yeast)  Symbol and/or name change 5135510 APPROVED