Mtmr3 (myotubularin related protein 3) - Rat Genome Database

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Gene: Mtmr3 (myotubularin related protein 3) Ictidomys tridecemlineatus
Analyze
Symbol: Mtmr3
Name: myotubularin related protein 3 (Ensembl:myotubularin-related protein 3-like)
RGD ID: 12611139
Description: ENCODES a protein that exhibits metal ion binding (inferred); phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity (inferred); phosphatidylinositol-3-phosphate phosphatase activity (inferred); INVOLVED IN cellular response to glucose starvation (inferred); phosphatidylinositol 5-phosphate metabolic process (inferred); phosphatidylinositol dephosphorylation (inferred); ASSOCIATED WITH Breast Cancer, Familial (ortholog); genetic disease (ortholog); vestibular schwannomatosis (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC101972939; myotubularin-related protein 3; myotubularin-related protein 3-like
RGD Orthologs
Human
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118111,819,583 - 111,830,880 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493721155,221 - 92,040 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493721167,199 - 92,204 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mtmr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118111,819,583 - 111,830,880 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493721155,221 - 92,040 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493721167,199 - 92,204 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTMR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382229,883,174 - 30,030,868 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2229,883,169 - 30,030,868 (+)EnsemblGRCh38hg38GRCh38
GRCh372230,279,163 - 30,426,857 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362228,609,158 - 28,756,857 (+)NCBINCBI36Build 36hg18NCBI36
Build 342228,603,752 - 28,748,423NCBI
Celera2214,078,881 - 14,226,583 (+)NCBICelera
Cytogenetic Map22q12.2NCBI
HuRef2213,241,277 - 13,388,890 (+)NCBIHuRef
CHM1_12230,238,335 - 30,386,025 (+)NCBICHM1_1
T2T-CHM13v2.02230,346,548 - 30,494,210 (+)NCBIT2T-CHM13v2.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021721534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000042322   ⟹   ENSSTOP00000031073
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493721155,221 - 92,040 (+)Ensembl
RefSeq Acc Id: XM_021721534   ⟹   XP_021577209
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118111,819,583 - 111,830,880 (-)NCBI
SpeTri2.0NW_00493721167,199 - 92,204 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_021577209 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000031073.1
Reference Protein Sequences
RefSeq Acc Id: XP_021577209   ⟸   XM_021721534
- Sequence:
RefSeq Acc Id: ENSSTOP00000031073   ⟸   ENSSTOT00000042322
Protein Domains
FYVE-type   Myotubularin phosphatase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000032750 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000042322.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro Myotubularin-like_Pase_dom UniProtKB/TrEMBL
  Myotubularin_fam UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Znf_FYVE UniProtKB/TrEMBL
  Znf_FYVE-rel UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene LOC101972939 ENTREZGENE
PANTHER MYOTUBULARIN-RELATED PROTEIN 3 UniProtKB/TrEMBL
  PTHR10807 UniProtKB/TrEMBL
Pfam FYVE UniProtKB/TrEMBL
  Myotub-related UniProtKB/TrEMBL
PROSITE PPASE_MYOTUBULARIN UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  ZF_FYVE UniProtKB/TrEMBL
SMART FYVE UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
UniProt A0A287DC02_ICTTR UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-26 Mtmr3  myotubularin related protein 3  LOC101972939  myotubularin-related protein 3-like  Symbol and/or name change 5135510 APPROVED