Primpol (primase and DNA directed polymerase) - Rat Genome Database

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Gene: Primpol (primase and DNA directed polymerase) Ictidomys tridecemlineatus
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Symbol: Primpol
Name: primase and DNA directed polymerase
RGD ID: 12610371
Description: ENCODES a protein that exhibits chromatin binding (inferred); DNA primase activity (inferred); DNA-directed DNA polymerase activity (inferred); INVOLVED IN DNA replication, synthesis of primer (inferred); error-prone translesion synthesis (inferred); mitochondrial DNA repair (inferred); ASSOCIATED WITH genetic disease (ortholog); Myopia 22, Autosomal Dominant (ortholog); FOUND IN mitochondrial matrix (inferred); nucleus (inferred); replication fork (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Ccdc111; coiled-coil domain containing 111; primase and DNA directed polymerase, transcript variant X1; primase and DNA directed polymerase, transcript variant X2; primase and DNA directed polymerase, transcript variant X3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494333,412,746 - 33,573,466 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365544,534,970 - 4,569,549 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365544,536,246 - 4,571,000 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Primpol
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494333,412,746 - 33,573,466 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365544,534,970 - 4,569,549 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365544,536,246 - 4,571,000 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRIMPOL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384184,649,738 - 184,694,952 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4184,649,667 - 184,694,963 (+)EnsemblGRCh38hg38GRCh38
GRCh374185,570,892 - 185,616,106 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364185,807,896 - 185,853,106 (+)NCBINCBI36Build 36hg18NCBI36
Celera4182,899,431 - 182,944,944 (+)NCBICelera
Cytogenetic Map4q35.1NCBI
HuRef4181,325,094 - 181,369,754 (+)NCBIHuRef
CHM1_14185,547,294 - 185,592,636 (+)NCBICHM1_1
T2T-CHM13v2.04187,993,422 - 188,038,703 (+)NCBIT2T-CHM13v2.0
Primpol
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39847,028,614 - 47,070,282 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl847,028,629 - 47,070,247 (-)EnsemblGRCm39 Ensembl
GRCm38846,575,579 - 46,617,227 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl846,575,594 - 46,617,212 (-)EnsemblGRCm38mm10GRCm38
MGSCv37847,660,948 - 47,702,554 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36848,074,411 - 48,116,017 (-)NCBIMGSCv36mm8
Celera849,258,170 - 49,299,782 (-)NCBICelera
Cytogenetic Map8B1.1NCBI
cM Map826.39NCBI
Primpol
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81652,413,894 - 52,450,975 (+)NCBIGRCr8
mRatBN7.21645,681,252 - 45,715,758 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1645,681,326 - 45,715,565 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01648,863,385 - 48,900,409 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1648,863,418 - 48,897,795 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01648,578,483 - 48,615,806 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41648,968,598 - 48,997,032 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1643,684,349 - 43,721,241 (+)NCBICelera
Cytogenetic Map16q11NCBI
Primpol
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540324,279,122 - 24,303,682 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540324,278,727 - 24,307,312 (-)NCBIChiLan1.0ChiLan1.0
PRIMPOL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23182,373,488 - 182,419,142 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14182,735,279 - 182,780,912 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04176,815,122 - 176,860,682 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14189,040,324 - 189,085,335 (+)NCBIpanpan1.1PanPan1.1panPan2
PRIMPOL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11645,861,244 - 45,920,183 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1645,856,042 - 45,918,761 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1646,354,134 - 46,412,999 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01648,076,787 - 48,135,773 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1648,070,581 - 48,135,753 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11646,042,091 - 46,100,919 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01646,656,725 - 46,715,297 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01646,789,466 - 46,848,402 (-)NCBIUU_Cfam_GSD_1.0
PRIMPOL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1545,709,710 - 45,819,919 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11545,764,261 - 45,851,052 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21552,463,747 - 52,518,946 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRIMPOL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17130,611,105 - 130,653,614 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7130,611,133 - 130,657,450 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037110,862,699 - 110,906,635 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Primpol
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476915,425,234 - 15,453,613 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476915,414,510 - 15,451,711 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSSTOT00000004914   ⟹   ENSSTOP00000004408
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365544,534,970 - 4,569,549 (-)Ensembl
RefSeq Acc Id: XM_005329223   ⟹   XP_005329280
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494333,539,075 - 33,573,466 (+)NCBI
SpeTri2.0NW_0049365544,536,246 - 4,571,000 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021729061   ⟹   XP_021584736
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494333,539,075 - 33,573,466 (+)NCBI
SpeTri2.0NW_0049365544,536,778 - 4,571,000 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021729062   ⟹   XP_021584737
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494333,539,075 - 33,573,466 (+)NCBI
SpeTri2.0NW_0049365544,536,778 - 4,569,460 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040294325   ⟹   XP_040150259
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494333,412,746 - 33,573,466 (+)NCBI
RefSeq Acc Id: XM_040294333   ⟹   XP_040150267
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494333,539,225 - 33,573,466 (+)NCBI
RefSeq Acc Id: XM_040294336   ⟹   XP_040150270
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494333,538,797 - 33,573,466 (+)NCBI
RefSeq Acc Id: XM_040294354   ⟹   XP_040150288
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494333,539,075 - 33,570,009 (+)NCBI
RefSeq Acc Id: XR_005737966
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494333,539,075 - 33,573,095 (+)NCBI
RefSeq Acc Id: XP_005329280   ⟸   XM_005329223
- Peptide Label: isoform X1
- UniProtKB: I3M541 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021584736   ⟸   XM_021729061
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021584737   ⟸   XM_021729062
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_040150259   ⟸   XM_040294325
- Peptide Label: isoform X1
- UniProtKB: I3M541 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040150270   ⟸   XM_040294336
- Peptide Label: isoform X1
- UniProtKB: I3M541 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040150288   ⟸   XM_040294354
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040150267   ⟸   XM_040294333
- Peptide Label: isoform X1
- UniProtKB: I3M541 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000004408   ⟸   ENSSTOT00000004914


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004912 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004914.3 UniProtKB/TrEMBL
InterPro DNA_primase_S UniProtKB/TrEMBL
  PRIMPOL UniProtKB/TrEMBL
NCBI Gene Primpol ENTREZGENE
PANTHER DNA-DIRECTED PRIMASE/POLYMERASE PROTEIN UniProtKB/TrEMBL
  PTHR31399 UniProtKB/TrEMBL
Pfam DNA_primase_S UniProtKB/TrEMBL
  Herpes_UL52 UniProtKB/TrEMBL
UniProt I3M541 ENTREZGENE, UniProtKB/TrEMBL