Efcab6 (EF-hand calcium binding domain 6) - Rat Genome Database

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Gene: Efcab6 (EF-hand calcium binding domain 6) Ictidomys tridecemlineatus
Analyze
Symbol: Efcab6
Name: EF-hand calcium binding domain 6
RGD ID: 12609326
Description: ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); Phelan-McDermid syndrome (ortholog); FOUND IN axonemal A tubule inner sheath (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: EF-hand calcium-binding domain-containing protein 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049455,455,456 - 5,687,089 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367181,293,322 - 1,517,952 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367181,293,088 - 1,501,664 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Efcab6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049455,455,456 - 5,687,089 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367181,293,322 - 1,517,952 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367181,293,088 - 1,501,664 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EFCAB6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382243,528,778 - 43,812,305 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2243,528,744 - 43,812,337 (-)EnsemblGRCh38hg38GRCh38
GRCh372243,924,658 - 44,208,185 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362242,255,987 - 42,539,451 (-)NCBINCBI36Build 36hg18NCBI36
Celera2227,835,968 - 28,119,513 (-)NCBICelera
Cytogenetic Map22q13.2-q13.31NCBI
HuRef2226,879,130 - 27,162,643 (-)NCBIHuRef
CHM1_12243,883,348 - 44,166,936 (-)NCBICHM1_1
T2T-CHM13v2.02244,011,227 - 44,295,198 (-)NCBIT2T-CHM13v2.0
Efcab6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391583,750,913 - 83,959,226 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1583,750,913 - 83,949,580 (-)EnsemblGRCm39 Ensembl
GRCm381583,866,712 - 84,075,025 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1583,866,712 - 84,065,379 (-)EnsemblGRCm38mm10GRCm38
MGSCv371583,697,142 - 83,895,779 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361583,694,478 - 83,893,115 (-)NCBIMGSCv36mm8
Celera1585,994,081 - 86,195,377 (-)NCBICelera
Cytogenetic Map15E1- E2NCBI
cM Map1539.48NCBI
Efcab6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87116,899,022 - 117,085,998 (-)NCBIGRCr8
mRatBN7.27115,018,971 - 115,200,121 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7115,019,010 - 115,206,092 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.07124,758,376 - 124,948,428 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7124,758,378 - 124,929,025 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07124,747,917 - 124,928,085 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47121,890,922 - 122,024,252 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17121,925,151 - 122,061,799 (-)NCBI
Celera7111,328,391 - 111,511,964 (-)NCBICelera
Cytogenetic Map7q34NCBI
Efcab6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541328,567,634 - 28,783,565 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541328,569,080 - 28,783,455 (-)NCBIChiLan1.0ChiLan1.0
EFCAB6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22353,346,432 - 53,639,641 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12256,039,219 - 56,333,005 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02224,414,362 - 24,700,901 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12242,608,067 - 42,893,414 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2242,608,067 - 42,893,414 (-)Ensemblpanpan1.1panPan2
EFCAB6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11021,829,783 - 22,064,034 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1021,831,430 - 22,064,030 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1021,770,460 - 22,004,508 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01022,578,629 - 22,812,813 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1022,580,306 - 22,812,813 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11022,297,954 - 22,531,928 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01022,618,101 - 22,851,011 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01022,792,207 - 23,026,524 (+)NCBIUU_Cfam_GSD_1.0
EFCAB6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.155,166,994 - 5,408,130 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.252,560,013 - 2,802,403 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EFCAB6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11926,023,566 - 26,327,309 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1926,023,643 - 26,295,493 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604599,076,207 - 99,384,797 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Efcab6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247525,313,804 - 5,552,248 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000004051   ⟹   ENSSTOP00000003635
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367181,293,322 - 1,517,952 (-)Ensembl
RefSeq Acc Id: XM_040281790   ⟹   XP_040137724
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049455,455,456 - 5,687,089 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040137724 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000003635.3
GenBank Protein KAG3290778 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040137724   ⟸   XM_040281790
RefSeq Acc Id: ENSSTOP00000003635   ⟸   ENSSTOT00000004051
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004012 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004051.3 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_DJBP UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
NCBI Gene Efcab6 ENTREZGENE
PANTHER EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6 UniProtKB/TrEMBL
  EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED UniProtKB/TrEMBL
Pfam EF-hand_11 UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt I3M3I3_ICTTR UniProtKB/TrEMBL