Mlxip (MLX interacting protein) - Rat Genome Database

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Gene: Mlxip (MLX interacting protein) Ictidomys tridecemlineatus
Analyze
Symbol: Mlxip
Name: MLX interacting protein
RGD ID: 12607899
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); protein dimerization activity (inferred); INVOLVED IN nucleocytoplasmic transport (ortholog); ASSOCIATED WITH Coronary Disease (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC101976350
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118157,108,248 - 157,162,495 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365582,321,231 - 2,371,178 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365582,316,938 - 2,371,172 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mlxip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118157,108,248 - 157,162,495 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365582,321,231 - 2,371,178 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365582,316,938 - 2,371,172 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MLXIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812122,078,756 - 122,147,344 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12122,078,756 - 122,147,344 (+)EnsemblGRCh38hg38GRCh38
GRCh3712122,516,662 - 122,631,891 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612121,177,744 - 121,194,942 (+)NCBINCBI36Build 36hg18NCBI36
Celera12122,201,038 - 122,218,235 (+)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12119,572,720 - 119,589,917 (+)NCBIHuRef
CHM1_112122,580,087 - 122,597,283 (+)NCBICHM1_1
CHM1_112122,484,942 - 122,493,214 (+)NCBICHM1_1
T2T-CHM13v2.012122,074,570 - 122,143,121 (+)NCBIT2T-CHM13v2.0
Mlxip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395123,532,438 - 123,595,998 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5123,532,861 - 123,595,995 (+)EnsemblGRCm39 Ensembl
GRCm385123,394,521 - 123,457,932 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5123,394,798 - 123,457,932 (+)EnsemblGRCm38mm10GRCm38
MGSCv375123,844,828 - 123,907,941 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365123,655,416 - 123,714,131 (+)NCBIMGSCv36mm8
Celera5120,482,164 - 120,544,846 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map562.95NCBI
Mlxip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81238,789,404 - 38,853,059 (-)NCBIGRCr8
mRatBN7.21233,128,524 - 33,192,300 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1233,128,520 - 33,192,374 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01238,567,438 - 38,638,952 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1238,567,247 - 38,638,536 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01240,443,314 - 40,510,190 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41234,271,250 - 34,287,210 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1234,811,820 - 34,875,479 (-)NCBICelera
Cytogenetic Map12q16NCBI
Mlxip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554826,411,890 - 6,456,580 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554826,410,182 - 6,456,582 (-)NCBIChiLan1.0ChiLan1.0
MLXIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210130,166,310 - 130,234,756 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112130,162,671 - 130,231,135 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012119,679,514 - 119,747,932 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112123,048,309 - 123,115,376 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12123,048,304 - 123,112,241 (+)Ensemblpanpan1.1panPan2
MLXIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1267,188,078 - 7,247,388 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl267,192,716 - 7,247,276 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha267,344,037 - 7,407,439 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0267,435,843 - 7,499,356 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl267,440,028 - 7,499,280 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1267,367,788 - 7,431,256 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0267,458,407 - 7,521,860 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,414,456 - 7,477,957 (-)NCBIUU_Cfam_GSD_1.0
MLXIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1430,577,661 - 30,646,243 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11430,575,098 - 30,646,275 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21432,288,338 - 32,305,140 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MLXIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111117,432,633 - 117,496,567 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11117,432,862 - 117,494,541 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666136271,286 - 336,472 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mlxip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474722,340,436 - 22,385,088 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474722,340,315 - 22,388,683 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005329656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000001761   ⟹   ENSSTOP00000001571
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365582,321,231 - 2,371,178 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000036075   ⟹   ENSSTOP00000026370
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365582,327,130 - 2,371,178 (-)Ensembl
RefSeq Acc Id: XM_005329656   ⟹   XP_005329713
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118157,108,248 - 157,162,495 (+)NCBI
SpeTri2.0NW_0049365582,316,938 - 2,371,172 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005329713 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000001571.3
  ENSSTOP00000026370.1
GenBank Protein KAG3279088 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005329713   ⟸   XM_005329656
- UniProtKB: I3LZ59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000001571   ⟸   ENSSTOT00000001761
RefSeq Acc Id: ENSSTOP00000026370   ⟸   ENSSTOT00000036075
Protein Domains
bHLH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000001742 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000001761.3 UniProtKB/TrEMBL
  ENSSTOT00000036075.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene Mlxip ENTREZGENE
PANTHER MLX-INTERACTING PROTEIN UniProtKB/TrEMBL
  PROTEIN MAX MYC-ASSOCIATED FACTOR X UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
UniProt A0A287CYF7_ICTTR UniProtKB/TrEMBL
  I3LZ59 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-09 Mlxip  MLX interacting protein  LOC101976350  MLX interacting protein  Symbol and/or name change 5135510 APPROVED
2021-03-26 LOC101976350  MLX interacting protein  Mlxip  MLX interacting protein  Symbol and/or name change 5135510 APPROVED