Samd4a (sterile alpha motif domain containing 4A) - Rat Genome Database

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Gene: Samd4a (sterile alpha motif domain containing 4A) Ictidomys tridecemlineatus
Analyze
Symbol: Samd4a
Name: sterile alpha motif domain containing 4A
RGD ID: 12606508
Description: ENCODES a protein that exhibits mRNA binding (inferred); RNA binding (inferred); translation repressor activity (inferred); INVOLVED IN positive regulation of translation (ortholog); ASSOCIATED WITH dystonia 5 (ortholog); genetic disease (ortholog); head and neck squamous cell carcinoma (ortholog); FOUND IN cell junction (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sterile alpha motif domain containing 4A, transcript variant X1; sterile alpha motif domain containing 4A, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864074,558,422 - 74,768,804 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936697336,981 - 541,150 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936697332,577 - 543,748 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Samd4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864074,558,422 - 74,768,804 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936697336,981 - 541,150 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936697332,577 - 543,748 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SAMD4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381454,565,316 - 54,793,315 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1454,566,117 - 54,793,315 (+)EnsemblGRCh38hg38GRCh38
GRCh371455,033,846 - 55,260,033 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361454,104,387 - 54,325,595 (+)NCBINCBI36Build 36hg18NCBI36
Build 341454,104,386 - 54,325,595NCBI
Celera1435,084,168 - 35,309,486 (+)NCBICelera
Cytogenetic Map14q22.2NCBI
HuRef1435,197,040 - 35,422,619 (+)NCBIHuRef
CHM1_11454,973,048 - 55,198,669 (+)NCBICHM1_1
T2T-CHM13v2.01448,771,187 - 48,998,510 (+)NCBIT2T-CHM13v2.0
Samd4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391447,120,414 - 47,343,274 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1447,120,311 - 47,343,272 (+)EnsemblGRCm39 Ensembl
GRCm381446,882,965 - 47,105,817 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1446,882,854 - 47,105,815 (+)EnsemblGRCm38mm10GRCm38
MGSCv371447,502,640 - 47,725,492 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361445,804,844 - 46,024,079 (+)NCBIMGSCv36mm8
MGSCv361438,712,160 - 38,932,128 (+)NCBIMGSCv36mm8
Celera1443,056,646 - 43,281,638 (+)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1424.41NCBI
Samd4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81522,616,200 - 22,831,872 (+)NCBIGRCr8
mRatBN7.21520,135,994 - 20,352,131 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1520,134,377 - 20,348,380 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1523,028,162 - 23,132,762 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01523,986,142 - 24,090,738 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01522,236,621 - 22,342,037 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01523,666,543 - 23,879,067 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1523,665,202 - 23,878,539 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01527,721,129 - 27,820,974 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41522,847,701 - 22,952,499 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11522,749,949 - 22,967,670 (+)NCBI
Celera1520,645,446 - 20,745,819 (+)NCBICelera
Cytogenetic Map15p14NCBI
Samd4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554098,712,061 - 8,916,816 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554098,716,432 - 8,916,398 (-)NCBIChiLan1.0ChiLan1.0
SAMD4A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21555,687,572 - 55,914,688 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11454,904,045 - 55,131,198 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01435,153,002 - 35,380,018 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11453,432,110 - 53,658,531 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1453,566,636 - 53,654,151 (+)Ensemblpanpan1.1panPan2
SAMD4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1830,476,425 - 30,687,240 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl830,476,418 - 30,687,240 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha830,243,508 - 30,455,649 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0830,732,570 - 30,943,425 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl830,732,557 - 30,945,114 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1830,336,559 - 30,547,600 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0830,412,983 - 30,623,593 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0830,778,494 - 30,989,083 (+)NCBIUU_Cfam_GSD_1.0
SAMD4A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1183,915,512 - 184,140,115 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11183,915,337 - 184,140,122 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21204,436,496 - 204,645,195 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SAMD4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12431,743,735 - 31,976,009 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2431,743,560 - 31,976,053 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605319,971,620 - 20,214,772 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Samd4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473114,537,065 - 14,742,406 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473114,537,063 - 14,744,703 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000015277   ⟹   ENSSTOP00000013688
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936697336,981 - 541,150 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000030162   ⟹   ENSSTOP00000028692
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936697336,981 - 541,150 (-)Ensembl
RefSeq Acc Id: XM_005337956   ⟹   XP_005338013
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864074,562,645 - 74,768,804 (-)NCBI
SpeTri2.0NW_004936697332,577 - 543,748 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735057   ⟹   XP_021590732
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864074,562,645 - 74,766,995 (-)NCBI
SpeTri2.0NW_004936697332,577 - 541,948 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040275619   ⟹   XP_040131553
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864074,558,422 - 74,661,050 (-)NCBI
RefSeq Acc Id: XM_040275620   ⟹   XP_040131554
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864074,562,645 - 74,661,050 (-)NCBI
RefSeq Acc Id: XM_040275621   ⟹   XP_040131555
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864074,558,422 - 74,661,050 (-)NCBI
RefSeq Acc Id: XM_040275622   ⟹   XP_040131556
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864074,558,422 - 74,596,961 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005338013   ⟸   XM_005337956
- Peptide Label: isoform X2
- UniProtKB: A0A287D585 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021590732   ⟸   XM_021735057
- Peptide Label: isoform X4
- UniProtKB: I3MPH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040131553   ⟸   XM_040275619
- Peptide Label: isoform X1
- UniProtKB: A0A287D585 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131555   ⟸   XM_040275621
- Peptide Label: isoform X5
- UniProtKB: A0A287D585 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131556   ⟸   XM_040275622
- Peptide Label: isoform X6
RefSeq Acc Id: XP_040131554   ⟸   XM_040275620
- Peptide Label: isoform X3
- UniProtKB: I3MPH2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000013688   ⟸   ENSSTOT00000015277
RefSeq Acc Id: ENSSTOP00000028692   ⟸   ENSSTOT00000030162
Protein Domains
SAM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015276 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015277.3 UniProtKB/TrEMBL
  ENSSTOT00000030162.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  1.25.40.170 UniProtKB/TrEMBL
InterPro PHAT_dom_sf UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  Smaug_SAM UniProtKB/TrEMBL
NCBI Gene Samd4a ENTREZGENE
PANTHER PROTEIN SMAUG HOMOLOG 1 UniProtKB/TrEMBL
  STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED UniProtKB/TrEMBL
Pfam SAM_1 UniProtKB/TrEMBL
SMART SAM UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
UniProt A0A287D585 ENTREZGENE, UniProtKB/TrEMBL
  I3MPH2 ENTREZGENE, UniProtKB/TrEMBL