Timp2 (TIMP metallopeptidase inhibitor 2) - Rat Genome Database
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Gene: Timp2 (TIMP metallopeptidase inhibitor 2) Ictidomys tridecemlineatus
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Symbol: Timp2
Name: TIMP metallopeptidase inhibitor 2
RGD ID: 12605149
Description: ENCODES a protein that exhibits enzyme activator activity (ortholog); integrin binding (ortholog); metalloendopeptidase inhibitor activity (ortholog); INVOLVED IN aging (ortholog); cellular response to organic substance (ortholog); central nervous system development (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); Alzheimer's disease (ortholog); Brain Injuries (ortholog); FOUND IN basement membrane (ortholog); cell surface (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: metalloproteinase inhibitor 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365943,232,433 - 3,244,241 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
Timp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365943,232,433 - 3,244,241 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TIMP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1778,852,977 - 78,925,387 (-)EnsemblGRCh38hg38GRCh38
GRCh381778,852,977 - 78,925,387 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371776,849,059 - 76,921,469 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361774,360,654 - 74,433,067 (-)NCBINCBI36hg18NCBI36
Build 341774,360,655 - 74,433,067NCBI
Celera1773,446,776 - 73,467,725 (-)NCBI
Cytogenetic Map17q25.3NCBI
HuRef1772,271,475 - 72,343,528 (-)NCBIHuRef
CHM1_11776,912,998 - 76,985,403 (-)NCBICHM1_1
Timp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911118,191,887 - 118,246,237 (-)NCBIGRCm39mm39
GRCm39 Ensembl11118,191,895 - 118,246,566 (-)Ensembl
GRCm3811118,301,061 - 118,355,411 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11118,301,069 - 118,355,740 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711118,162,375 - 118,216,725 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611118,117,151 - 118,171,501 (-)NCBImm8
Celera11130,046,014 - 130,100,382 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1183.09NCBI
Timp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.210103,541,199 - 103,590,611 (-)NCBI
Rnor_6.0 Ensembl10107,338,465 - 107,386,072 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.010107,338,465 - 107,386,072 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010106,973,463 - 107,021,070 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410108,310,473 - 108,358,821 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110108,324,976 - 108,373,325 (-)NCBI
Celera10102,103,187 - 102,150,797 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
Timp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555063,768,646 - 3,813,820 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555063,769,113 - 3,812,896 (+)NCBIChiLan1.0ChiLan1.0
TIMP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11778,476,807 - 78,495,885 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1778,476,807 - 78,495,649 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01772,928,692 - 73,001,892 (-)NCBIMhudiblu_PPA_v0panPan3
TIMP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl92,521,882 - 2,533,989 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.192,521,882 - 2,533,883 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
TIMP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl123,254,493 - 3,300,835 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1123,254,794 - 3,300,835 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2123,294,254 - 3,340,447 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TIMP2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11670,819,591 - 70,850,471 (-)NCBI
ChlSab1.1 Ensembl1670,819,139 - 70,850,471 (-)Ensembl
Timp2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248018,228,618 - 8,270,606 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005332623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGTP01070656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005332623   ⟹   XP_005332680
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365943,232,433 - 3,244,241 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005332680 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005332680   ⟸   XM_005332623
- UniProtKB: I3MQW3 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
NTR


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000016084 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000014397 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000016085 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.120 UniProtKB/TrEMBL
  3.90.370.10 UniProtKB/TrEMBL
InterPro Netrin_domain UniProtKB/TrEMBL
  TIMP UniProtKB/TrEMBL
  TIMP-like_OB-fold UniProtKB/TrEMBL
  TIMP2 UniProtKB/TrEMBL
  TIMP_C UniProtKB/TrEMBL
NCBI Gene Timp2 ENTREZGENE
PANTHER PTHR11844 UniProtKB/TrEMBL
  PTHR11844:SF24 UniProtKB/TrEMBL
Pfam TIMP UniProtKB/TrEMBL
PROSITE NTR UniProtKB/TrEMBL
SMART NTR UniProtKB/TrEMBL
Superfamily-SCOP SSF50242 UniProtKB/TrEMBL
UniProt I3MQW3 ENTREZGENE, UniProtKB/TrEMBL