Cst7 (cystatin F) - Rat Genome Database

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Gene: Cst7 (cystatin F) Ictidomys tridecemlineatus
Analyze
Symbol: Cst7
Name: cystatin F
RGD ID: 12601568
Description: ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity (inferred); peptidase inhibitor activity (inferred); protein homodimerization activity (inferred); INVOLVED IN negative regulation of microglial cell activation (ortholog); positive regulation of myelination (ortholog); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic vesicle (inferred); endoplasmic reticulum (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cystatin F, transcript variant X1; cystatin F, transcript variant X2; cystatin F, transcript variant X3; cystatin-F
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640147,435,685 - 147,450,362 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936620853,439 - 870,812 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936620853,533 - 870,609 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cst7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640147,435,685 - 147,450,362 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936620853,439 - 870,812 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936620853,533 - 870,609 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CST7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382024,949,269 - 24,959,928 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2024,949,269 - 24,959,928 (+)EnsemblGRCh38hg38GRCh38
GRCh372024,929,905 - 24,940,564 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362024,877,866 - 24,888,562 (+)NCBINCBI36Build 36hg18NCBI36
Build 342024,877,865 - 24,888,562NCBI
Celera2025,003,521 - 25,014,368 (+)NCBICelera
Cytogenetic Map20p11.21NCBI
HuRef2024,886,598 - 24,897,456 (+)NCBIHuRef
CHM1_12024,930,375 - 24,941,053 (+)NCBICHM1_1
T2T-CHM13v2.02025,013,382 - 25,024,201 (+)NCBIT2T-CHM13v2.0
Cst7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392150,412,335 - 150,420,864 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2150,412,335 - 150,420,864 (+)EnsemblGRCm39 Ensembl
GRCm382150,570,415 - 150,578,944 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2150,570,415 - 150,578,944 (+)EnsemblGRCm38mm10GRCm38
MGSCv372150,396,151 - 150,404,680 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362150,261,875 - 150,270,383 (+)NCBIMGSCv36mm8
Celera2151,805,324 - 151,813,854 (+)NCBICelera
Cytogenetic Map2G3NCBI
cM Map274.67NCBI
Cst7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83159,857,221 - 159,865,987 (+)NCBIGRCr8
mRatBN7.23139,396,830 - 139,405,557 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3139,396,850 - 139,405,557 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3143,293,599 - 143,302,310 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03151,877,342 - 151,886,053 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03149,625,444 - 149,634,155 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03146,363,913 - 146,373,365 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3146,365,092 - 146,373,365 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03152,726,245 - 152,736,007 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43141,188,442 - 141,199,756 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13141,074,327 - 141,104,838 (+)NCBI
Celera3138,160,316 - 138,169,038 (+)NCBICelera
Cytogenetic Map3q41NCBI
Cst7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541531,082,978 - 31,086,379 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541531,082,978 - 31,086,379 (+)NCBIChiLan1.0ChiLan1.0
CST7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22125,820,558 - 25,831,580 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12025,817,391 - 25,828,414 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02024,889,834 - 24,900,766 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12025,237,251 - 25,248,364 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2025,237,251 - 25,248,364 (+)Ensemblpanpan1.1panPan2
CST7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1231,136,161 - 1,145,411 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl231,136,258 - 1,144,983 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha231,166,587 - 1,175,839 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0231,379,118 - 1,388,571 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl231,379,217 - 1,388,143 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1231,194,770 - 1,204,020 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0231,324,938 - 1,334,191 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0231,307,878 - 1,317,130 (+)NCBIUU_Cfam_GSD_1.0
CST7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1730,758,000 - 30,766,472 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11730,758,000 - 30,766,472 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21734,906,655 - 34,915,135 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Cst7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624939471,706 - 475,545 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624939471,699 - 475,338 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000005882   ⟹   ENSSTOP00000005261
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936620853,439 - 870,812 (-)Ensembl
RefSeq Acc Id: XM_005334592   ⟹   XP_005334649
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640147,435,685 - 147,450,339 (-)NCBI
SpeTri2.0NW_004936620853,533 - 870,609 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021732729   ⟹   XP_021588404
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640147,435,685 - 147,450,362 (-)NCBI
SpeTri2.0NW_004936620857,128 - 870,609 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005334649 (Get FASTA)   NCBI Sequence Viewer  
  XP_021588404 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000005261.3
GenBank Protein KAG3262735 (Get FASTA)   NCBI Sequence Viewer  
  KAG3262736 (Get FASTA)   NCBI Sequence Viewer  
  KAG3262737 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005334649   ⟸   XM_005334592
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021588404   ⟸   XM_021732729
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSSTOP00000005261   ⟸   ENSSTOT00000005882
Protein Domains
Cystatin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000005896 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000005882.3 UniProtKB/TrEMBL
Gene3D-CATH 3.10.450.10 UniProtKB/TrEMBL
InterPro Cystatin-F UniProtKB/TrEMBL
  Cystatin_dom UniProtKB/TrEMBL
  Cystatin_sf UniProtKB/TrEMBL
NCBI Gene Cst7 ENTREZGENE
PANTHER CYSTATIN-F UniProtKB/TrEMBL
  PTHR47141 UniProtKB/TrEMBL
Pfam Cystatin UniProtKB/TrEMBL
SMART SM00043 UniProtKB/TrEMBL
Superfamily-SCOP SSF54403 UniProtKB/TrEMBL
UniProt I3M6V3_ICTTR UniProtKB/TrEMBL