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Gene: Top2b (DNA topoisomerase II beta) Ictidomys tridecemlineatus
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Symbol: Top2b
Name: DNA topoisomerase II beta
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (ortholog); enzyme binding (ortholog); INVOLVED IN axonogenesis (ortholog); cell aging (ortholog); cellular response to ATP (ortholog); PARTICIPATES IN etoposide pharmacodynamics pathway; etoposide pharmacokinetics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); myeloid leukemia (ortholog); prostate carcinoma in situ (ortholog); FOUND IN cytosol (ortholog); heterochromatin (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA topoisomerase 2-beta; topoisomerase (DNA) II beta; topoisomerase (DNA) II beta 180kDa
Orthologs:
Homo sapiens (human) : TOP2B (DNA topoisomerase II beta)  HGNC  Alliance
Mus musculus (house mouse) : Top2b (topoisomerase (DNA) II beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Top2b (DNA topoisomerase II beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Top2b (DNA topoisomerase II beta)
Pan paniscus (bonobo/pygmy chimpanzee) : TOP2B (DNA topoisomerase II beta)
Canis lupus familiaris (dog) : TOP2B (DNA topoisomerase II beta)
Sus scrofa (pig) : TOP2B (DNA topoisomerase II beta)
Chlorocebus sabaeus (African green monkey) : TOP2B (DNA topoisomerase II beta)
Heterocephalus glaber (naked mole-rat) : Top2b (DNA topoisomerase II beta)
more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647317,146,576 - 17,189,589 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
 
More on Top2b
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12598632
Created: 2017-01-27
Species: Ictidomys tridecemlineatus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.