Appl2 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2) - Rat Genome Database

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Gene: Appl2 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2) Ictidomys tridecemlineatus
Analyze
Symbol: Appl2
Name: adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
RGD ID: 12598525
Description: ENCODES a protein that exhibits identical protein binding (ortholog); phosphatidylinositol binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN adiponectin-activated signaling pathway (ortholog); cellular response to hepatocyte growth factor stimulus (ortholog); cold acclimation (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); substance-related disorder (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); early phagosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: DCC-interacting protein 13-beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494516,467,066 - 16,530,048 (+)NCBI
SpeTri2.0NW_0049364929,477,483 - 9,526,692 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
Appl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494516,467,066 - 16,530,048 (+)NCBI
SpeTri2.0NW_0049364929,477,483 - 9,526,692 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APPL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12105,173,297 - 105,236,203 (-)EnsemblGRCh38hg38GRCh38
GRCh3812105,173,297 - 105,236,174 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712105,567,078 - 105,629,952 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612104,091,205 - 104,154,138 (-)NCBINCBI36hg18NCBI36
Celera12105,231,366 - 105,294,273 (-)NCBI
Cytogenetic Map12q23.3NCBI
HuRef12102,626,453 - 102,689,404 (-)NCBIHuRef
CHM1_112105,532,775 - 105,595,738 (-)NCBICHM1_1
Appl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391083,435,897 - 83,484,741 (-)NCBIGRCm39mm39
GRCm39 Ensembl1083,435,897 - 83,484,602 (-)Ensembl
GRCm381083,600,033 - 83,648,877 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1083,600,033 - 83,648,738 (-)EnsemblGRCm38mm10GRCm38
MGSCv371083,062,778 - 83,111,409 (-)NCBIGRCm37mm9NCBIm37
MGSCv361083,029,832 - 83,078,463 (-)NCBImm8
Celera1085,587,519 - 85,636,067 (-)NCBICelera
Cytogenetic Map10C1NCBI
Appl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2720,135,248 - 20,184,757 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl720,135,375 - 20,184,754 (+)Ensembl
Rnor_6.0726,256,179 - 26,306,128 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl726,256,459 - 26,306,126 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0726,387,115 - 26,436,564 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4722,279,273 - 22,328,427 (+)NCBIRGSC3.4rn4RGSC3.4
Celera717,339,053 - 17,386,872 (+)NCBICelera
Cytogenetic Map7q13NCBI
Appl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540539,503,020 - 39,540,335 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540539,503,020 - 39,540,069 (-)NCBIChiLan1.0ChiLan1.0
APPL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112106,150,955 - 106,214,038 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12106,151,969 - 106,206,879 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012102,755,388 - 102,818,686 (-)NCBIMhudiblu_PPA_v0panPan3
APPL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11033,192,261 - 33,243,034 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1033,191,602 - 33,242,669 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1033,111,933 - 33,162,406 (+)NCBI
ROS_Cfam_1.01034,033,756 - 34,084,221 (+)NCBI
UMICH_Zoey_3.11033,769,093 - 33,819,698 (+)NCBI
UNSW_CanFamBas_1.01034,053,225 - 34,103,854 (+)NCBI
UU_Cfam_GSD_1.01034,246,325 - 34,297,170 (+)NCBI
APPL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl579,356,047 - 79,412,233 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1579,356,046 - 79,412,235 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2582,650,763 - 82,706,934 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap5q2.3NCBI
APPL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111100,400,093 - 100,469,234 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl11100,400,084 - 100,462,507 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037144,551,093 - 144,614,465 (+)NCBIVero_WHO_p1.0
Appl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247503,789,015 - 3,827,079 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005322333   ⟹   XP_005322390
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494516,467,066 - 16,516,278 (+)NCBI
SpeTri2.0NW_0049364929,477,484 - 9,526,692 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013357301   ⟹   XP_013212755
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494516,467,066 - 16,516,275 (+)NCBI
SpeTri2.0NW_0049364929,477,483 - 9,526,692 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005731179
RefSeq Status:
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494516,467,066 - 16,530,048 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005322390 (Get FASTA)   NCBI Sequence Viewer  
  XP_013212755 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3291110 (Get FASTA)   NCBI Sequence Viewer  
  KAG3291111 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013212755   ⟸   XM_013357301
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005322390   ⟸   XM_005322333
- Peptide Label: isoform X1
- UniProtKB: I3MMQ6 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014326 ENTREZGENE
Ensembl Protein ENSSTOP00000012839 ENTREZGENE
NCBI Gene Appl2 ENTREZGENE
UniProt I3MMQ6 ENTREZGENE