Lipf (lipase F, gastric type) - Rat Genome Database

Name: Lipf
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Lipf (lipase F, gastric type) Ictidomys tridecemlineatus

Analyze

Symbol:

Lipf

Name:

lipase F, gastric type

RGD ID:

12598344

Description:

ENCODES a protein that exhibits malate dehydrogenase activity (ortholog); INVOLVED IN malate metabolic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); PTEN hamartoma tumor syndrome (ortholog); FOUND IN mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

gastric triacylglycerol lipase; lipase F, gastric type, transcript variant X1; lipase F, gastric type, transcript variant X2

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LIPF (lipase F, gastric type)	NCBI	Ortholog
Mus musculus (house mouse):	Lipf (lipase, gastric)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Lipf (lipase F, gastric type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Lipf (lipase F, gastric type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LIPF (lipase F, gastric type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LIPF (lipase F, gastric type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LIPF (lipase F, gastric type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lipf (lipase F, gastric type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	78,221,590 - 78,239,486 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936735	553,438 - 568,021 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936735	553,438 - 568,021 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

PTEN hamartoma tumor syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lipid catabolic process (IEA)

malate metabolic process (ISO)

Cellular Component

extracellular region (IEA)

mitochondrion (ISO)

Molecular Function

hydrolase activity (IEA)

hydrolase activity, acting on ester bonds (IEA)

malate dehydrogenase activity (ISO)

protein binding (ISO)

triglyceride lipase activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Lipf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	78,221,590 - 78,239,486 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936735	553,438 - 568,021 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936735	553,438 - 568,021 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LIPF
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	88,664,442 - 88,678,814 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	88,664,441 - 88,678,814 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	90,424,199 - 90,438,571 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	90,414,074 - 90,428,552 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	90,414,195 - 90,428,542	NCBI
Celera	10	84,170,927 - 84,185,402 (+)	NCBI		Celera
Cytogenetic Map	10	q23.31	NCBI
HuRef	10	84,058,693 - 84,073,122 (+)	NCBI		HuRef
CHM1_1	10	90,706,220 - 90,720,626 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	89,548,553 - 89,562,923 (+)	NCBI		T2T-CHM13v2.0

Lipf
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	33,938,648 - 33,954,213 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	33,938,587 - 33,954,210 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	33,961,248 - 33,976,813 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	33,961,187 - 33,976,810 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	34,035,738 - 34,051,303 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	34,027,245 - 34,042,810 (+)	NCBI		MGSCv36	mm8
Celera	19	34,737,801 - 34,753,366 (+)	NCBI		Celera
Cytogenetic Map	19	C1	NCBI
cM Map	19	29.29	NCBI

Lipf
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	240,906,706 - 240,925,053 (+)	NCBI		GRCr8
mRatBN7.2	1	231,493,498 - 231,511,845 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	231,493,498 - 231,511,845 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	239,877,083 - 239,895,430 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	246,806,295 - 246,824,661 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	239,644,366 - 239,662,731 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	252,284,464 - 252,302,811 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	252,284,464 - 252,302,811 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	259,507,653 - 259,526,000 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	237,838,238 - 237,856,579 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	238,005,561 - 238,020,602 (+)	NCBI
Celera	1	228,607,481 - 228,625,828 (+)	NCBI		Celera
Cytogenetic Map	1	q52	NCBI

Lipf
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	4,267,004 - 4,285,078 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	4,267,977 - 4,284,996 (-)	NCBI	ChiLan1.0	ChiLan1.0

LIPF
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	100,682,450 - 100,696,947 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	100,687,930 - 100,702,262 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	85,389,165 - 85,403,492 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	88,892,525 - 88,906,898 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	88,892,525 - 88,906,898 (+)	Ensembl	panpan1.1		panPan2

LIPF
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	38,469,876 - 38,486,881 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	38,424,721 - 38,588,175 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	38,286,752 - 38,303,738 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	40,054,032 - 40,071,028 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	40,054,032 - 40,071,016 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	37,893,844 - 37,910,828 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	37,489,480 - 37,506,494 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	38,759,547 - 38,776,548 (+)	NCBI		UU_Cfam_GSD_1.0

LIPF
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	82,095,036 - 82,107,539 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	82,095,601 - 82,106,765 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	42,772,803 - 42,786,976 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lipf
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624791	14,961,557 - 14,972,238 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624791	14,961,554 - 14,972,310 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005339187	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005339188	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000007781 ⟹ ENSSTOP00000006967

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936735	553,438 - 568,021 (-)	Ensembl

RefSeq Acc Id:

XM_005339187 ⟹ XP_005339244

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	78,221,590 - 78,239,486 (+)	NCBI
SpeTri2.0	NW_004936735	553,438 - 568,021 (-)	NCBI

Sequence:

show sequence

AATGTGGTCGCTTTTAGCAGTGGCAAGTTTGATATCTGCATTTGGAACTACGCATGGTTTCTTA
GGAAAAGTAGCACCTGAGAGCCCTGAAGCCCACATGAATATTAATCAAATGATTTCCTACTGGG
GATACCCAAGTGAAGAATATGAAGTTGTGACTGAAGACGGTTATATCCTTGGGGTCTTCAGAAT
TCCTTATGGAAAGAAAAACTCAGAGAACAAAGGCCACAGACCTGTGGTGTTTCTGCAGCATGGT
TTGCTTGCATCAGCCACAAACTGGATTGCAAACCTGCCCAACAACAGTCTGGCCTTCATTCTGG
CAGACGCTGGTTATGACGTGTGGTTGGGCAACAGCAGAGGAAATACCTGGTCCAGGAGAAATTT
GTACTATTCACCAGACTCAGTTGAATTCTGGGCTTTCAGTTTTGATGAAATGGCTAAATATGAC
CTTCCAGCCACAATTGACTTCATTGTAAAGAAAACGGGGCAGGAGAAGATACACTATGTTGGTC
ATTCTCAGGGCACCACCATTGGTTTTATTGCCTTTTCTACCAATCCCACACTGGCTAGAAGAAT
CAAAACCTTTTATGCATTAGCTCCAGTTGCCACTGTGAAGTACGCAACAAGCCCTTTAACAAAA
CTTTCACTTATTCCATCACCCCTCTTCAAGATCATATTTGGTGACAGAATATTCCTCCCACACA
ACTTCTTTTATGGATTTCTTGGTACTGAAGTGTGCTCCCGAGAGCTAATGGATCTCCTTTGTAG
CAATGCATTGTTTATCATGTGTGGATTTGACAGTAAGAACTTGAATACGAGTCGCTTCGATGTC
TATCTGGCACATAATCCAGCAGGAACTTCTGTTCAAGATGTCCTCCACTGGGCCCAGGCTGCTA
GGTCTGGAAAATTTCAAGCTTTTGACTGGGGAAGCCCATTTCAGAACATGAGACACTATAATCA
GCGCACACCTCCCTACTACAATGTGACAGCCATGAGTGTGCCGATTGCAGTGTGGAATGGTGGC
AATGACATTTTGGCTGACCCCCACGACGTCAACATTTTGCTTCCCAAACTCTCCAATCTCATTT
ACCACAAGGAGATTCTTCCTTACAACCACTTGGATTTTATCTGGGCAATTAACGCTCCACAAAA
GGTTTACAATGAAATTGTTTCTATGATGTCAGAAGATAAAGAATAGCTGTGGATTTTAGAAATT
TTTCACTTCTTTTTCCAAAATGCTTTTCTTTCTCATGAACAGTTTTCGGCAATGTATAAAACCC
AGTGCTTCTTTCTGTAATTTTGACTTTAGAAATAAATTGGCATCCATAAAC

hide sequence

Protein Sequences


Protein RefSeqs	XP_005339244	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000006967.3
GenBank Protein	KAG3264919	(Get FASTA)	NCBI Sequence Viewer
	KAG3264920	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005339244 ⟸ XM_005339187

- UniProtKB:

I3MAE9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MWSLLAVASLISAFGTTHGFLGKVAPESPEAHMNINQMISYWGYPSEEYEVVTEDGYILGVFRI
PYGKKNSENKGHRPVVFLQHGLLASATNWIANLPNNSLAFILADAGYDVWLGNSRGNTWSRRNL
YYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQEKIHYVGHSQGTTIGFIAFSTNPTLARRI
KTFYALAPVATVKYATSPLTKLSLIPSPLFKIIFGDRIFLPHNFFYGFLGTEVCSRELMDLLCS
NALFIMCGFDSKNLNTSRFDVYLAHNPAGTSVQDVLHWAQAARSGKFQAFDWGSPFQNMRHYNQ
RTPPYYNVTAMSVPIAVWNGGNDILADPHDVNILLPKLSNLIYHKEILPYNHLDFIWAINAPQK
VYNEIVSMMSEDKE

hide sequence

RefSeq Acc Id:

ENSSTOP00000006967 ⟸ ENSSTOT00000007781

Protein Domains

AB hydrolase-1

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000007782	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000007781.3	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1820	UniProtKB/TrEMBL
InterPro	AB_hydrolase	UniProtKB/TrEMBL
	AB_hydrolase_1	UniProtKB/TrEMBL
	Lipase_euk	UniProtKB/TrEMBL
NCBI Gene	Lipf	ENTREZGENE
PANTHER	LYSOSOMAL ACID LIPASE-RELATED	UniProtKB/TrEMBL
	PTHR11005:SF15	UniProtKB/TrEMBL
Pfam	Abhydrolase_1	UniProtKB/TrEMBL
PIRSF	Steryl_ester_lip	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53474	UniProtKB/TrEMBL
UniProt	I3MAE9	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar