Esco2 (establishment of sister chromatid cohesion N-acetyltransferase 2) - Rat Genome Database

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Gene: Esco2 (establishment of sister chromatid cohesion N-acetyltransferase 2) Ictidomys tridecemlineatus
Analyze
Symbol: Esco2
Name: establishment of sister chromatid cohesion N-acetyltransferase 2
RGD ID: 12594980
Description: ENCODES a protein that exhibits acetyltransferase activity (inferred); acyltransferase activity (inferred); lysine N-acetyltransferase activity, acting on acetyl phosphate as donor (inferred); INVOLVED IN chromosome segregation (ortholog); double-strand break repair (ortholog); hematopoietic progenitor cell differentiation (ortholog); ASSOCIATED WITH autosomal dominant nocturnal frontal lobe epilepsy (ortholog); benign familial infantile seizures 6 (ortholog); genetic disease (ortholog); FOUND IN cell junction (inferred); chromatin (inferred); chromocenter (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: N-acetyltransferase ESCO2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049437,885,816 - 7,916,735 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936675670,915 - 697,668 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936675670,915 - 697,696 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Esco2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049437,885,816 - 7,916,735 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936675670,915 - 697,668 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936675670,915 - 697,696 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESCO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38827,771,974 - 27,819,660 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl827,771,949 - 27,812,640 (+)EnsemblGRCh38hg38GRCh38
GRCh37827,632,071 - 27,662,833 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36827,687,977 - 27,718,344 (+)NCBINCBI36Build 36hg18NCBI36
Celera826,591,951 - 26,622,299 (+)NCBICelera
Cytogenetic Map8p21.1NCBI
HuRef826,176,933 - 26,207,305 (+)NCBIHuRef
CHM1_1827,833,977 - 27,864,365 (+)NCBICHM1_1
T2T-CHM13v2.0828,046,848 - 28,097,943 (+)NCBIT2T-CHM13v2.0
Esco2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391466,056,476 - 66,071,418 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1466,056,487 - 66,071,443 (-)EnsemblGRCm39 Ensembl
GRCm381465,819,027 - 65,833,969 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1465,819,038 - 65,833,994 (-)EnsemblGRCm38mm10GRCm38
MGSCv371466,437,864 - 66,452,806 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361464,773,148 - 64,787,994 (-)NCBIMGSCv36mm8
Celera1463,572,076 - 63,587,018 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.36NCBI
Esco2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81544,210,124 - 44,230,785 (-)NCBIGRCr8
mRatBN7.21540,034,566 - 40,052,295 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1540,034,568 - 40,055,306 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01542,500,929 - 42,519,019 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1542,500,929 - 42,518,855 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01549,072,219 - 49,091,726 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41545,239,871 - 45,254,898 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1539,706,954 - 39,724,684 (-)NCBICelera
Cytogenetic Map15p12NCBI
Esco2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540350,307,681 - 50,372,822 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540350,306,726 - 50,328,015 (+)NCBIChiLan1.0ChiLan1.0
ESCO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2746,308,606 - 46,351,625 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1822,022,865 - 22,065,888 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0827,049,858 - 27,080,396 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1824,250,435 - 24,281,007 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl824,251,557 - 24,284,001 (+)Ensemblpanpan1.1panPan2
ESCO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12529,785,641 - 29,812,536 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2529,787,132 - 29,811,112 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2530,439,599 - 30,464,378 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02529,978,376 - 30,003,256 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2529,978,379 - 30,003,186 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12529,908,235 - 29,932,879 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02529,789,703 - 29,814,487 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02529,956,082 - 29,981,766 (-)NCBIUU_Cfam_GSD_1.0
ESCO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11411,495,297 - 11,532,898 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21412,674,855 - 12,710,818 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ESCO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1825,885,823 - 25,919,863 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl825,887,309 - 25,916,630 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605216,220,597 - 16,252,214 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Esco2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475822,578,528 - 22,600,804 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475822,578,565 - 22,600,731 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005337246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000000493   ⟹   ENSSTOP00000000445
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936675670,915 - 697,668 (+)Ensembl
RefSeq Acc Id: XM_005337246   ⟹   XP_005337303
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049437,885,816 - 7,916,735 (-)NCBI
SpeTri2.0NW_004936675670,915 - 697,696 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005337303 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000000445.3
GenBank Protein KAG3294310 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005337303   ⟸   XM_005337246
- UniProtKB: I3LWR5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000000445   ⟸   ENSSTOT00000000493
Protein Domains
N-acetyltransferase ESCO acetyl-transferase   N-acetyltransferase ESCO zinc-finger


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000493 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000493.3 UniProtKB/TrEMBL
InterPro AcTrfase_ESCO_Znf_dom UniProtKB/TrEMBL
  ESCO_Acetyltransf_dom UniProtKB/TrEMBL
NCBI Gene Esco2 ENTREZGENE
PANTHER N-ACETYLTRANSFERASE ECO UniProtKB/TrEMBL
  N-ACETYLTRANSFERASE ESCO2 UniProtKB/TrEMBL
Pfam Acetyltransf_13 UniProtKB/TrEMBL
  zf-C2H2_3 UniProtKB/TrEMBL
UniProt I3LWR5 ENTREZGENE, UniProtKB/TrEMBL