Zcchc12 (zinc finger CCHC-type containing 12)

Gene: Zcchc12 (zinc finger CCHC-type containing 12) Ictidomys tridecemlineatus

Analyze

Symbol:

Zcchc12

Name:

zinc finger CCHC-type containing 12

RGD ID:

12592781

Description:

ENCODES a protein that exhibits SUMO binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH autistic disorder (ortholog); esophagus squamous cell carcinoma (ortholog); genetic disease (ortholog); FOUND IN nuclear speck (ortholog); PML body (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC106144687; uncharacterized LOC106144687; zinc finger CCHC domain-containing protein 12

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	89,962,878 - 89,965,993 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936479	11,021,502 - 11,024,612 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

esophagus squamous cell carcinoma (ISO)

genetic disease (ISO)

syndromic X-linked intellectual disability Cabezas type (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

BMP signaling pathway (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

Cellular Component

nuclear speck (ISO)

nucleus (IEA)

PML body (ISO)

Molecular Function

protein binding (ISO)

SUMO binding (ISO)

transcription coactivator activity (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Zcchc12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	89,962,878 - 89,965,993 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936479	11,021,502 - 11,024,612 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZCCHC12
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	118,823,824 - 118,826,968 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	118,823,824 - 118,826,968 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	117,957,787 - 117,960,931 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	117,841,815 - 117,844,959 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	117,739,668 - 117,742,812	NCBI
Celera	X	118,412,636 - 118,415,780 (+)	NCBI		Celera
Cytogenetic Map	X	q24	NCBI
HuRef	X	107,450,846 - 107,453,876 (+)	NCBI		HuRef
CHM1_1	X	117,868,691 - 117,871,835 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	117,201,557 - 117,204,701 (+)	NCBI		T2T-CHM13v2.0

Zcchc12
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	35,459,553 - 35,462,817 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	35,459,557 - 35,462,811 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	36,195,904 - 36,199,164 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	36,195,904 - 36,199,158 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	33,735,899 - 33,739,153 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	32,627,433 - 32,630,595 (+)	NCBI		MGSCv36	mm8
Celera	X	22,924,652 - 22,927,906 (+)	NCBI		Celera
Cytogenetic Map	X	A3.3	NCBI
cM Map	X	20.58	NCBI

Zcchc12
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	120,299,138 - 120,302,465 (+)	NCBI		GRCr8
mRatBN7.2	X	115,433,444 - 115,436,691 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	115,433,259 - 115,436,692 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	117,535,737 - 117,538,922 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	121,104,821 - 121,108,006 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	118,651,026 - 118,654,211 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	122,808,581 - 122,811,790 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	122,808,605 - 122,811,789 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	122,958,348 - 122,961,547 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	8,729,463 - 8,732,648 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	8,735,023 - 8,738,204 (-)	NCBI
Celera	X	114,669,169 - 114,672,354 (+)	NCBI		Celera
Cytogenetic Map	X	q34	NCBI

Zcchc12
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955534	1,132,104 - 1,133,312 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955534	1,131,585 - 1,133,382 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZCCHC12
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	118,182,772 - 118,185,927 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	118,186,377 - 118,189,531 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	107,831,784 - 107,834,964 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	118,297,824 - 118,301,054 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	118,299,326 - 118,300,534 (+)	Ensembl	panpan1.1		panPan2

ZCCHC12
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	91,004,777 - 91,008,019 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	77,078,676 - 77,081,923 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	92,743,141 - 92,746,388 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	92,743,139 - 92,746,387 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	90,196,340 - 90,199,587 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	91,955,078 - 91,958,325 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	91,683,385 - 91,686,632 (+)	NCBI		UU_Cfam_GSD_1.0

ZCCHC12
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666065	31,565,021 - 31,568,265 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Zcchc12
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624895	2,806,703 - 2,807,908 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624895	2,805,303 - 2,808,429 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021722390	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040284733	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_021722390 ⟹ XP_021578065

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	89,962,878 - 89,965,993 (+)	NCBI
SpeTri2.0	NW_004936479	11,021,502 - 11,024,612 (-)	NCBI

Sequence:

show sequence

CCGCAGAGGATAAAAGCAGCCGCAGCTGCCTCGGAATCGCGCTGCCGCGTCTCGGCTCCCCCTC
GCTGGGTGGCCGTGCGAGGCAGTTCCATCGGGCATCTCTGGGCCGCTTAGCTGCGGAAGAGGCG
CTCGTCTTTTTCCTTTACAGGGCTGCGGAGATTAGAAGGCGGAATCCATAGCTGTGGACGCTGG
AGCACACCGTTAGCAGCGGGTTGCAGCTTATCAAAGACGAAAACCTGAACTTTAATTCTGCGCA
GTTGACTGATACAGCTGTCTTGACGCCCTAAGCACAGGGTTCTACAAACCCGGAGGTGAGCTTT
CTCAGAGGGCACCGGTTGCAGAGCTTGAACCTGAAAAAAGCCTCCACTGAAATCGGAAGAAGGA
AGAGCACCGCAACATCTGCAGATTAGGCTTTTATTTCTAAAAAGCCTGAGCATCGTGTATTCAG
ATACCCTATCATTGTTAGGCATGGCTAGTATTATTGCACGTGTGGGTAGCCGTCGGCAGAATGC
GCCGTTGCCGCCTTGGGCCCATTCCATGCTGAGGTCCCTGGGCAGGAGTCTTGGGCCTTTGATG
GCCAGCATGGCAGACAGAAATATGAAGTTTTTCTCGGGGAGGGCGGTGCCAGCACAGGGGGAAG
AAACCTTTGAAAACTGGCTGGCCCAAGTCAATGGGGTCCTGCCAGACTGGAATATGTCTGAGGA
GGAAAAGCTGAAGCGCTTGATGAAAACCCTTAGGGGCCCTGCTCGAGAGGTCATGCGTTTGCTC
CAAGCTGCCAACCCCAACCTAAGTGTGGCAGATTTTTTGCGAGCAATGAAACTGGTGTTTGGGG
AATCTGAGAGCAGTGTGACCGCGCATGGTAATTTTTTTAACACCTTGCAGGCCCAAGGGGAGAA
AGCCTCCCTTTACGTGATCCGTTTGGAGGTGCAGCTCCAGAATGCTATTCAGGCAGGCATCTTA
GCTGAGAAGGATGCCAACCAGACTCGCCTGCACCAGCTCCTCATAGGAGCTGAGCTGAATAGAA
ATCTGCGCTTCAGGCTTCAGGGTCTTCTCAGGATGTATGCAAATGAGCAGGAGCAGCTTCCCAA
TTTCCTGGAGTTAATCAGGATGATAAGGGAGGAAGAGGATTGGGATGACACTTTTATTAAACGG
AAGCGGCCCAAGAGATCTGAGTCAGTGGTGGAGGGGGCAGACAGCCCCGGAGCATTTCAGGGCT
CCCTGCCTGTAGCAATTGGCAGTGACGACTGTAATGTGATAGAAATAGATGATACCCTTGATGA
CTCAGATGAGGATGTGATCCTAGTGGAGTCTGGGGACCCTCCACTGTCATCCCCAGGTGCTCCT
CCCTTCAGGGGAAGGGCCAGATCTCAGGACCAAGTGTTGGTCATTGATCCCCCCAGTAATTTTG
GAACCGAGGCTCCTTCCACCAGCAGTGGTTCTGGACATAAGATTAATGGTCCTAGGGATATGCG
CAGAGCCAGGAAGCGAAAACACACAACTCGCTGTTCCTTTTGTGGGGAGGAAGGACACTCAAAA
GAAACCTGTGATAATGAGAGCAACAAGACCCAGGTTTTTGAGAATCTGATCATCACCCTGCAGG
AGTTGACACATACAGAGGAGGAGGGGTCAGGAGAGGCCCGTGGTGAATCCAGTGATTCCTCTGA
GCCACAGTAAGGTGCTAGCCCCCATCCTTAAATGAACCATTTCCCATATTCAGAGTTTGGTGAT
GGGAAAATTAGGAAAGGGGGAGTTCTAATTGCATGAGTTAATCTACAAAGCGGCTTTCTTTTGT
CACGGAGAAGGGGTCTCATATTACCAGTATAGTGGAAGGGGATGTCCTGACCTTTAGGCTTGCT
TCCTTTTCCCACTGCCTAAGAGTCTATTTTCTGTGTGTGCCCATTTCTTTGATGGCTTTATGCT
CTTTGTGAAAGTTGTATGATTCATTGCTAAATCTTTAAATGATAAAAGTTCAAAAAGTAAAGTA
TGTTACCCTTGAACTCACCACCCTTATTTAACCATTGTCAGCCCTTGTGGTGAATGTCTTTCTG
GATATTTTCCTGTACCTATGAACCCAGATAGATATATGTATAGATAAAAGTGACCAAATATAAG
TGCTGTTCTATATGCTGTATTTTTTCACCAAACAATATATGTTGTGAGCTTCTATGTCAATAAA
TATATCAGCATCTACTTTAA

hide sequence

RefSeq Acc Id:

XM_040284733 ⟹ XP_040140667

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	89,962,878 - 89,965,993 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_021578065	(Get FASTA)	NCBI Sequence Viewer
	XP_040140667	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000022104.1
GenBank Protein	KAG3272803	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_021578065 ⟸ XM_021722390

- UniProtKB:

I3NCK7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASIIARVGSRRQNAPLPPWAHSMLRSLGRSLGPLMASMADRNMKFFSGRAVPAQGEETFENWL
AQVNGVLPDWNMSEEEKLKRLMKTLRGPAREVMRLLQAANPNLSVADFLRAMKLVFGESESSVT
AHGNFFNTLQAQGEKASLYVIRLEVQLQNAIQAGILAEKDANQTRLHQLLIGAELNRNLRFRLQ
GLLRMYANEQEQLPNFLELIRMIREEEDWDDTFIKRKRPKRSESVVEGADSPGAFQGSLPVAIG
SDDCNVIEIDDTLDDSDEDVILVESGDPPLSSPGAPPFRGRARSQDQVLVIDPPSNFGTEAPST
SSGSGHKINGPRDMRRARKRKHTTRCSFCGEEGHSKETCDNESNKTQVFENLIITLQELTHTEE
EGSGEARGESSDSSEPQ

hide sequence

RefSeq Acc Id:	XP_040140667 ⟸ XM_040284733
- UniProtKB:	I3NCK7 (UniProtKB/TrEMBL)

Protein Domains

Paraneoplastic antigen Ma-like C-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000022238	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000020616.1	UniProtKB/TrEMBL
InterPro	PNMA	UniProtKB/TrEMBL
	PNMA_C	UniProtKB/TrEMBL
NCBI Gene	LOC106144687	ENTREZGENE
PANTHER	PTHR23095	UniProtKB/TrEMBL
	ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 12	UniProtKB/TrEMBL
Pfam	PNMA	UniProtKB/TrEMBL
UniProt	I3NCK7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-07-14	Zcchc12	zinc finger CCHC-type containing 12	Zcchc12	zinc finger CCHC-type containing 12	Data merged from RGD:12727393	737654	PROVISIONAL
2017-07-13	Zcchc12	zinc finger CCHC-type containing 12	LOC106144687	uncharacterized LOC106144687	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD