Rufy4 (RUN and FYVE domain containing 4) - Rat Genome Database

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Gene: Rufy4 (RUN and FYVE domain containing 4) Ictidomys tridecemlineatus
Analyze
Symbol: Rufy4
Name: RUN and FYVE domain containing 4
RGD ID: 12591414
Description: ENCODES a protein that exhibits metal ion binding (inferred); phosphatidylinositol-3-phosphate binding (inferred); INVOLVED IN autophagosome assembly (inferred); cellular response to interleukin-4 (inferred); positive regulation of macroautophagy (inferred); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN autophagosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: RUN and FYVE domain containing 4, transcript variant X1; RUN and FYVE domain containing 4, transcript variant X2; RUN and FYVE domain containing 4, transcript variant X3; RUN and FYVE domain-containing protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303174,312,123 - 174,333,037 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936569657,071 - 675,292 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936569654,904 - 676,012 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rufy4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303174,312,123 - 174,333,037 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936569657,071 - 675,292 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936569654,904 - 676,012 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RUFY4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382218,034,934 - 218,090,652 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2218,034,960 - 218,090,584 (+)EnsemblGRCh38hg38GRCh38
GRCh372218,899,657 - 218,955,307 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,646,285 - 218,663,108 (+)NCBINCBI36Build 36hg18NCBI36
Celera2212,667,545 - 212,721,497 (+)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2210,753,571 - 210,795,629 (+)NCBIHuRef
HuRef2210,806,734 - 210,808,063 (+)NCBIHuRef
CHM1_12218,906,131 - 218,961,799 (+)NCBICHM1_1
T2T-CHM13v2.02218,519,258 - 218,576,350 (+)NCBIT2T-CHM13v2.0
Rufy4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,163,768 - 74,187,389 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl174,164,700 - 74,187,382 (+)EnsemblGRCm39 Ensembl
GRCm38174,124,433 - 74,148,230 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,125,541 - 74,148,223 (+)EnsemblGRCm38mm10GRCm38
MGSCv37174,172,115 - 74,194,804 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36174,058,748 - 74,081,430 (+)NCBIMGSCv36mm8
Celera174,686,822 - 74,709,585 (+)NCBICelera
Cytogenetic Map1C3NCBI
cM Map138.38NCBI
Rufy4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8983,152,139 - 83,172,683 (+)NCBIGRCr8
mRatBN7.2975,702,937 - 75,727,719 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl975,703,750 - 75,723,525 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0981,401,080 - 81,422,016 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,402,124 - 81,421,990 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,166,869 - 81,187,696 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,446,811 - 73,464,490 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera973,280,221 - 73,301,145 (+)NCBICelera
Cytogenetic Map9q33NCBI
Rufy4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545315,242,954 - 15,257,976 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545315,243,125 - 15,259,086 (-)NCBIChiLan1.0ChiLan1.0
RUFY4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213120,704,607 - 120,726,807 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B120,719,574 - 120,741,774 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B105,331,522 - 105,353,934 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B223,930,456 - 223,952,939 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B223,932,041 - 223,952,939 (+)Ensemblpanpan1.1panPan2
RUFY4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13724,809,365 - 24,830,254 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3724,809,359 - 24,829,724 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3725,629,499 - 25,650,965 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03724,825,220 - 24,846,781 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3724,827,074 - 24,845,718 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13724,730,722 - 24,752,283 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03724,665,154 - 24,686,674 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03724,684,349 - 24,705,920 (+)NCBIUU_Cfam_GSD_1.0
RUFY4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15120,192,235 - 120,213,462 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115120,193,657 - 120,213,625 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215133,247,484 - 133,269,106 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RUFY4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110103,958,208 - 103,979,948 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10103,958,495 - 103,979,410 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604095,415,317 - 95,437,513 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rufy4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248236,908,636 - 6,925,863 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248236,908,113 - 6,927,724 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000024432   ⟹   ENSSTOP00000019344
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936569657,071 - 675,292 (+)Ensembl
RefSeq Acc Id: XM_013360850   ⟹   XP_013216304
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303174,312,123 - 174,333,037 (+)NCBI
SpeTri2.0NW_004936569654,904 - 676,012 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013216304 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000019344.1
GenBank Protein KAG3275212 (Get FASTA)   NCBI Sequence Viewer  
  KAG3275213 (Get FASTA)   NCBI Sequence Viewer  
  KAG3275214 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_013216304   ⟸   XM_013360850
- UniProtKB: I3N4P8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000019344   ⟸   ENSSTOT00000024432
Protein Domains
FYVE-type   RUN


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000024826 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024432.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.900 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro RUFY4 UniProtKB/TrEMBL
  Run_dom UniProtKB/TrEMBL
  Run_dom_sf UniProtKB/TrEMBL
  Znf_FYVE UniProtKB/TrEMBL
  Znf_FYVE-rel UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene Rufy4 ENTREZGENE
PANTHER PTHR47732 UniProtKB/TrEMBL
  RUN AND FYVE DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
Pfam RUN UniProtKB/TrEMBL
PROSITE RUN UniProtKB/TrEMBL
  ZF_FYVE UniProtKB/TrEMBL
SMART FYVE UniProtKB/TrEMBL
Superfamily-SCOP SSF140741 UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
UniProt I3N4P8 ENTREZGENE, UniProtKB/TrEMBL