Rabep1 (rabaptin, RAB GTPase binding effector protein 1) - Rat Genome Database

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Gene: Rabep1 (rabaptin, RAB GTPase binding effector protein 1) Ictidomys tridecemlineatus
Analyze
Symbol: Rabep1
Name: rabaptin, RAB GTPase binding effector protein 1
RGD ID: 12590431
Description: ENCODES a protein that exhibits growth factor activity (inferred); GTPase activator activity (inferred); protein domain specific binding (inferred); INVOLVED IN regulation of postsynaptic neurotransmitter receptor internalization (ortholog); ASSOCIATED WITH fetal akinesia deformation sequence syndrome 4 (ortholog); genetic disease (ortholog); teratoma (ortholog); FOUND IN glutamatergic synapse (ortholog); presynaptic cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rab GTPase-binding effector protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560253,419,365 - 53,483,299 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366772,417,679 - 2,512,868 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366772,417,676 - 2,481,587 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rabep1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560253,419,365 - 53,483,299 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366772,417,679 - 2,512,868 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366772,417,676 - 2,481,587 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RABEP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38175,282,284 - 5,386,340 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl175,282,265 - 5,386,340 (+)EnsemblGRCh38hg38GRCh38
GRCh37175,185,579 - 5,289,660 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36175,126,282 - 5,229,856 (+)NCBINCBI36Build 36hg18NCBI36
Build 34175,126,308 - 5,229,855NCBI
Celera175,202,076 - 5,305,503 (+)NCBICelera
Cytogenetic Map17p13.2NCBI
HuRef175,076,120 - 5,179,776 (+)NCBIHuRef
CHM1_1175,194,871 - 5,298,790 (+)NCBICHM1_1
T2T-CHM13v2.0175,176,049 - 5,280,075 (+)NCBIT2T-CHM13v2.0
Rabep1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,735,553 - 70,833,931 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,735,604 - 70,833,931 (+)EnsemblGRCm39 Ensembl
GRCm381170,844,724 - 70,943,105 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,844,778 - 70,943,105 (+)EnsemblGRCm38mm10GRCm38
MGSCv371170,658,265 - 70,756,607 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,661,120 - 70,757,135 (+)NCBIMGSCv36mm8
Celera1178,399,194 - 78,497,475 (+)NCBICelera
Cytogenetic Map11B3- B4NCBI
cM Map1143.21NCBI
Rabep1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81056,064,742 - 56,168,778 (+)NCBIGRCr8
mRatBN7.21055,566,156 - 55,667,595 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1055,566,185 - 55,665,973 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1060,246,541 - 60,345,682 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01059,735,063 - 59,834,201 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01055,234,142 - 55,333,286 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01057,462,272 - 57,579,901 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1057,462,447 - 57,579,898 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01057,207,704 - 57,326,469 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41057,746,747 - 57,847,498 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11057,760,369 - 57,861,121 (+)NCBI
Celera1054,712,478 - 54,811,806 (+)NCBICelera
Cytogenetic Map10q24NCBI
Rabep1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546710,613,861 - 10,747,255 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546710,613,671 - 10,748,122 (+)NCBIChiLan1.0ChiLan1.0
RABEP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21912,892,660 - 12,996,355 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11714,860,602 - 14,964,572 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0175,330,477 - 5,434,250 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1175,344,966 - 5,426,160 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl175,344,966 - 5,426,160 (+)Ensemblpanpan1.1panPan2
RABEP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1531,390,873 - 31,442,585 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl531,391,576 - 31,491,506 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha531,528,879 - 31,630,006 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0531,495,500 - 31,595,348 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl531,495,489 - 31,595,357 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1531,461,067 - 31,562,173 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0531,419,943 - 31,521,587 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0531,596,383 - 31,697,964 (-)NCBIUU_Cfam_GSD_1.0
RABEP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1251,602,226 - 51,858,206 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11251,602,228 - 51,868,180 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21253,899,560 - 53,926,902 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RABEP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1164,670,448 - 4,795,309 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl164,670,499 - 4,792,689 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605916,792,952 - 16,904,507 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rabep1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247869,060,895 - 9,191,767 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247869,060,953 - 9,191,767 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013363807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000003237   ⟹   ENSSTOP00000002890
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366772,420,206 - 2,482,294 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000034271   ⟹   ENSSTOP00000024045
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366772,417,679 - 2,512,868 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000035228   ⟹   ENSSTOP00000024380
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366772,420,862 - 2,481,588 (-)Ensembl
RefSeq Acc Id: XM_013363807   ⟹   XP_013219261
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560253,419,365 - 53,483,299 (+)NCBI
SpeTri2.0NW_0049366772,417,676 - 2,481,587 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013219261 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000002890.3
  ENSSTOP00000024045.1
  ENSSTOP00000024380.1
GenBank Protein KAG3270092 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_013219261   ⟸   XM_013363807
- UniProtKB: I3M1W9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000024045   ⟸   ENSSTOT00000034271
RefSeq Acc Id: ENSSTOP00000002890   ⟸   ENSSTOT00000003237
RefSeq Acc Id: ENSSTOP00000024380   ⟸   ENSSTOT00000035228
Protein Domains
Rabaptin coiled-coil   Rabaptin GTPase-Rab5 binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000003225 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000003237.3 UniProtKB/TrEMBL
  ENSSTOT00000034271.1 UniProtKB/TrEMBL
  ENSSTOT00000035228.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.340 UniProtKB/TrEMBL
  Single helix bin UniProtKB/TrEMBL
InterPro Rabaptin UniProtKB/TrEMBL
  Rabaptin_coiled-coil UniProtKB/TrEMBL
  Rabaptin_Rab5-bd_dom UniProtKB/TrEMBL
NCBI Gene Rabep1 ENTREZGENE
PANTHER PTHR31179 UniProtKB/TrEMBL
  PTHR31179:SF5 UniProtKB/TrEMBL
Pfam Rab5-bind UniProtKB/TrEMBL
  Rabaptin UniProtKB/TrEMBL
PRINTS RABAPTIN UniProtKB/TrEMBL
Superfamily-SCOP G protein-binding domain UniProtKB/TrEMBL
UniProt A0A287CRU0_ICTTR UniProtKB/TrEMBL
  A0A287CSS1_ICTTR UniProtKB/TrEMBL
  I3M1W9 ENTREZGENE, UniProtKB/TrEMBL