Etv3 (ETS variant transcription factor 3) - Rat Genome Database

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Gene: Etv3 (ETS variant transcription factor 3) Ictidomys tridecemlineatus
Analyze
Symbol: Etv3
Name: ETS variant transcription factor 3
RGD ID: 12589881
Description: ENCODES a protein that exhibits DEAD/H-box RNA helicase binding (inferred); DNA binding (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); parathyroid carcinoma (ortholog); FOUND IN chromatin (inferred); intracellular membrane-bounded organelle (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ETS translocation variant 3; ETS variant 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,204,235 - 27,219,001 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365806,237,701 - 6,247,231 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365806,234,038 - 6,249,339 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Etv3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,204,235 - 27,219,001 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365806,237,701 - 6,247,231 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365806,234,038 - 6,249,339 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ETV3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381157,121,191 - 157,138,395 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1157,121,191 - 157,138,474 (-)EnsemblGRCh38hg38GRCh38
GRCh371157,090,983 - 157,108,187 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361155,369,600 - 155,374,801 (-)NCBINCBI36Build 36hg18NCBI36
Build 341153,916,050 - 153,921,250NCBI
Celera1130,165,650 - 130,179,574 (-)NCBICelera
Cytogenetic Map1q23.1NCBI
HuRef1128,452,734 - 128,466,660 (-)NCBIHuRef
CHM1_11158,490,846 - 158,504,773 (-)NCBICHM1_1
T2T-CHM13v2.01156,258,040 - 156,275,241 (-)NCBIT2T-CHM13v2.0
Etv3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39387,432,891 - 87,447,463 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl387,432,714 - 87,447,463 (+)EnsemblGRCm39 Ensembl
GRCm38387,525,577 - 87,540,158 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl387,525,407 - 87,540,156 (+)EnsemblGRCm38mm10GRCm38
MGSCv37387,329,500 - 87,344,078 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36387,611,525 - 87,625,522 (+)NCBIMGSCv36mm8
Celera387,558,676 - 87,573,235 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.19NCBI
Etv3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82175,263,389 - 175,278,217 (+)NCBIGRCr8
mRatBN7.22172,965,461 - 172,980,320 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2172,965,588 - 172,980,314 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2180,117,095 - 180,125,163 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02178,139,427 - 178,147,495 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02172,728,805 - 172,736,874 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02186,872,483 - 186,887,294 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2186,872,520 - 186,886,592 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02206,277,234 - 206,292,038 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42179,567,146 - 179,576,683 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12179,433,675 - 179,526,745 (+)NCBI
Celera2166,918,803 - 166,928,341 (+)NCBICelera
Cytogenetic Map2q34NCBI
LOC100993377
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2192,705,168 - 92,719,644 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1192,440,889 - 92,457,965 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01132,464,426 - 132,481,638 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11136,285,256 - 136,302,330 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1136,285,256 - 136,302,330 (-)Ensemblpanpan1.1panPan2
ETV3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1740,954,104 - 40,968,544 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl740,956,024 - 40,966,190 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha740,441,349 - 40,455,757 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0740,816,553 - 40,830,929 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl740,816,578 - 40,831,146 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1740,598,866 - 40,613,241 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0740,651,779 - 40,666,153 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0740,935,103 - 40,949,482 (+)NCBIUU_Cfam_GSD_1.0
ETV3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl492,964,941 - 92,979,122 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1492,964,808 - 92,979,129 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24101,424,237 - 101,436,974 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ETV3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1206,736,208 - 6,753,576 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl206,736,327 - 6,753,544 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660386,011,401 - 6,028,761 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Etv3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248852,217,433 - 2,232,305 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248852,218,766 - 2,232,395 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021730557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000026938   ⟹   ENSSTOP00000018137
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365806,237,701 - 6,247,231 (-)Ensembl
RefSeq Acc Id: XM_021730557   ⟹   XP_021586232
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,204,235 - 27,219,001 (-)NCBI
SpeTri2.0NW_0049365806,234,038 - 6,249,339 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_021586232 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000018137.1
Reference Protein Sequences
RefSeq Acc Id: XP_021586232   ⟸   XM_021730557
- UniProtKB: I3N191 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000018137   ⟸   ENSSTOT00000026938
Protein Domains
ETS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000022630 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000026938.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro Ets_dom UniProtKB/TrEMBL
  ETS_fam UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene Etv3 ENTREZGENE
PANTHER ETS TRANSLOCATION VARIANT 3-LIKE PROTEIN UniProtKB/TrEMBL
  PTHR11849 UniProtKB/TrEMBL
Pfam Ets UniProtKB/TrEMBL
PRINTS ETSDOMAIN UniProtKB/TrEMBL
PROSITE ETS_DOMAIN_1 UniProtKB/TrEMBL
  ETS_DOMAIN_2 UniProtKB/TrEMBL
  ETS_DOMAIN_3 UniProtKB/TrEMBL
SMART ETS UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt I3N191 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-11-27 Etv3  ETS variant transcription factor 3  Etv3  ETS variant 3  Symbol and/or name change 5135510 APPROVED