Nup188 (nucleoporin 188) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Nup188 (nucleoporin 188) Ictidomys tridecemlineatus
Analyze
Symbol: Nup188
Name: nucleoporin 188
RGD ID: 12588649
Description: ENCODES a protein that exhibits structural constituent of nuclear pore (inferred); INVOLVED IN mRNA transport (inferred); nucleocytoplasmic transport (inferred); protein import into nucleus (inferred); ASSOCIATED WITH congenital disorder of glycosylation (ortholog); congenital disorder of glycosylation Im (ortholog); genetic disease (ortholog); FOUND IN nuclear envelope (inferred); nuclear pore (inferred); nuclear pore inner ring (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nucleoporin NUP188; nucleoporin NUP188 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,639,939 - 196,694,386 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648716,408,518 - 16,462,923 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648716,408,523 - 16,462,916 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nup188
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,639,939 - 196,694,386 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648716,408,518 - 16,462,923 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648716,408,523 - 16,462,916 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUP188
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389128,947,699 - 129,007,096 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9128,947,699 - 129,007,096 (+)EnsemblGRCh38hg38GRCh38
GRCh379131,709,978 - 131,769,375 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,749,798 - 130,809,195 (+)NCBINCBI36Build 36hg18NCBI36
Build 349128,789,563 - 128,848,928NCBI
Celera9102,361,838 - 102,421,686 (+)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9101,317,691 - 101,376,696 (+)NCBIHuRef
CHM1_19131,861,021 - 131,920,403 (+)NCBICHM1_1
T2T-CHM13v2.09141,151,108 - 141,210,530 (+)NCBIT2T-CHM13v2.0
Nup188
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39230,176,419 - 30,234,278 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl230,176,409 - 30,234,278 (+)EnsemblGRCm39 Ensembl
GRCm38230,286,407 - 30,344,266 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl230,286,397 - 30,344,266 (+)EnsemblGRCm38mm10GRCm38
MGSCv37230,141,953 - 30,199,782 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36230,108,442 - 30,166,271 (+)NCBIMGSCv36mm8
Celera229,991,190 - 30,049,297 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.49NCBI
Nup188
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8333,957,778 - 34,014,122 (+)NCBIGRCr8
mRatBN7.2313,559,917 - 13,616,313 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,559,990 - 13,616,307 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.038,852,271 - 8,908,608 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,873,933 - 8,908,438 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0314,205,251 - 14,261,382 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.439,331,812 - 9,388,204 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera38,326,493 - 8,382,816 (+)NCBICelera
Cytogenetic Map3p12NCBI
Nup188
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555701,312,998 - 1,369,513 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555701,312,998 - 1,369,513 (+)NCBIChiLan1.0ChiLan1.0
NUP188
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21110,346,228 - 10,404,809 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1910,348,576 - 10,407,139 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09100,069,656 - 100,130,521 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,733,749 - 128,791,252 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,733,780 - 128,791,252 (+)Ensemblpanpan1.1panPan2
NUP188
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1954,657,520 - 54,712,900 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl954,657,682 - 54,712,827 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha953,853,072 - 53,908,426 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0955,578,563 - 55,633,941 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl955,578,567 - 55,633,921 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1954,340,129 - 54,395,076 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0954,652,331 - 54,707,442 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0954,745,638 - 54,800,996 (-)NCBIUU_Cfam_GSD_1.0
NUP188
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1269,259,519 - 269,312,862 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11269,259,496 - 269,312,872 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21303,275,625 - 303,328,996 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NUP188
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1129,150,603 - 9,213,512 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl129,151,005 - 9,208,452 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666096299,833 - 407,072 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nup188
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247606,111,621 - 6,118,084 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla_female_1.0 EnsemblNW_0046247606,061,130 - 6,106,853 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247606,061,130 - 6,120,597 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000002135   ⟹   ENSSTOP00000001903
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648716,416,069 - 16,462,525 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000041188   ⟹   ENSSTOP00000029484
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648716,408,518 - 16,462,923 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000043090   ⟹   ENSSTOP00000024763
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648716,408,518 - 16,462,923 (+)Ensembl
RefSeq Acc Id: XM_005321059   ⟹   XP_005321116
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947196,639,939 - 196,693,998 (+)NCBI
SpeTri2.0NW_00493648716,408,523 - 16,462,525 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723612   ⟹   XP_021579287
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947196,639,981 - 196,694,386 (+)NCBI
SpeTri2.0NW_00493648716,408,523 - 16,462,916 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723614   ⟹   XP_021579289
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947196,639,939 - 196,694,386 (+)NCBI
SpeTri2.0NW_00493648716,408,523 - 16,462,916 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040286467   ⟹   XP_040142401
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947196,639,981 - 196,694,386 (+)NCBI
RefSeq Acc Id: XM_040286468   ⟹   XP_040142402
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947196,639,981 - 196,694,386 (+)NCBI
RefSeq Acc Id: XM_040286469   ⟹   XP_040142403
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947196,639,939 - 196,694,386 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005321116   ⟸   XM_005321059
- Peptide Label: isoform X6
- UniProtKB: A0A287CU12 (UniProtKB/TrEMBL),   I3LZU6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021579287   ⟸   XM_021723612
- Peptide Label: isoform X3
- UniProtKB: A0A287D7H1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021579289   ⟸   XM_021723614
- Peptide Label: isoform X5
- UniProtKB: I3LZU6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040142403   ⟸   XM_040286469
- Peptide Label: isoform X4
- UniProtKB: I3LZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040142401   ⟸   XM_040286467
- Peptide Label: isoform X1
- UniProtKB: A0A287D7H1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040142402   ⟸   XM_040286468
- Peptide Label: isoform X2
- UniProtKB: A0A287D7H1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000001903   ⟸   ENSSTOT00000002135
RefSeq Acc Id: ENSSTOP00000029484   ⟸   ENSSTOT00000041188
RefSeq Acc Id: ENSSTOP00000024763   ⟸   ENSSTOT00000043090
Protein Domains
Nucleoporin Nup188 N-terminal   Nucleoporin Nup188 N-terminal subdomain III


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000002110 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000002135.3 UniProtKB/TrEMBL
  ENSSTOT00000041188.1 UniProtKB/TrEMBL
  ENSSTOT00000043090.1 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  Nucleoporin_Nup188_N UniProtKB/TrEMBL
  Nup188 UniProtKB/TrEMBL
  Nup188_N-subdom_III UniProtKB/TrEMBL
NCBI Gene Nup188 ENTREZGENE
PANTHER NUCLEOPORIN NUP188 UniProtKB/TrEMBL
  PTHR31431 UniProtKB/TrEMBL
Pfam Nup188 UniProtKB/TrEMBL
  Nup188_N-subdom_III UniProtKB/TrEMBL
  Nup188_SH3-like UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A287CU12 ENTREZGENE, UniProtKB/TrEMBL
  A0A287D7H1 ENTREZGENE, UniProtKB/TrEMBL
  I3LZU6 ENTREZGENE, UniProtKB/TrEMBL