Dis3l2 (DIS3 like 3'-5' exoribonuclease 2)

Gene: Dis3l2 (DIS3 like 3'-5' exoribonuclease 2) Ictidomys tridecemlineatus

Analyze

Symbol:

Dis3l2

Name:

DIS3 like 3'-5' exoribonuclease 2

RGD ID:

12584988

Description:

ENCODES a protein that exhibits 3'-5' exonuclease activity (inferred); 3'-5'-RNA exonuclease activity (inferred); exonuclease activity (inferred); INVOLVED IN nuclear-transcribed mRNA catabolic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatoblastoma (ortholog); Joubert syndrome 22 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); P-body (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

DIS3 like 3'-5' exoribonuclease 2, transcript variant X1; DIS3 like 3'-5' exoribonuclease 2, transcript variant X10; DIS3 like 3'-5' exoribonuclease 2, transcript variant X11; DIS3 like 3'-5' exoribonuclease 2, transcript variant X12; DIS3 like 3'-5' exoribonuclease 2, transcript variant X13; DIS3 like 3'-5' exoribonuclease 2, transcript variant X14; DIS3 like 3'-5' exoribonuclease 2, transcript variant X15; DIS3 like 3'-5' exoribonuclease 2, transcript variant X2; DIS3 like 3'-5' exoribonuclease 2, transcript variant X3; DIS3 like 3'-5' exoribonuclease 2, transcript variant X4; DIS3 like 3'-5' exoribonuclease 2, transcript variant X5; DIS3 like 3'-5' exoribonuclease 2, transcript variant X6; DIS3 like 3'-5' exoribonuclease 2, transcript variant X7; DIS3 like 3'-5' exoribonuclease 2, transcript variant X8; DIS3 like 3'-5' exoribonuclease 2, transcript variant X9; DIS3 mitotic control homolog (S. cerevisiae)-like 2; DIS3-like exonuclease 2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	185,881,165 - 186,220,945 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936525	4,719,121 - 5,008,014 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936525	4,718,773 - 5,058,512 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

hepatoblastoma (ISO)

Joubert syndrome 22 (ISO)

nephroblastoma (ISO)

Neurodevelopmental Disorders (ISO)

osteochondrodysplasia (ISO)

Perlman syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell division (IEA)

miRNA catabolic process (IEA)

mitotic cell cycle (IEA)

mitotic sister chromatid separation (IEA)

mRNA catabolic process (IEA)

negative regulation of cell population proliferation (IEA)

nuclear-transcribed mRNA catabolic process (ISO)

polyuridylation-dependent mRNA catabolic process (IEA)

stem cell population maintenance (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

P-body (IEA)

Molecular Function

3'-5' exonuclease activity (IEA)

3'-5'-RNA exonuclease activity (IEA)

exonuclease activity (IEA)

magnesium ion binding (IEA)

metal ion binding (IEA)

poly(U) RNA binding (IEA)

protein binding (ISO)

RNA binding (IEA)

RNA exonuclease activity, producing 5'-phosphomonoesters (IEA)

RNA nuclease activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Dis3l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	185,881,165 - 186,220,945 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936525	4,719,121 - 5,008,014 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936525	4,718,773 - 5,058,512 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DIS3L2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	231,961,713 - 232,344,350 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	231,961,245 - 232,344,350 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	232,826,423 - 233,209,060 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	232,534,537 - 232,910,152 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	226,589,534 - 226,966,072 (+)	NCBI		Celera
Cytogenetic Map	2	q37.1	NCBI
HuRef	2	224,677,041 - 225,059,431 (+)	NCBI		HuRef
CHM1_1	2	232,832,242 - 233,214,871 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	232,448,342 - 232,831,055 (+)	NCBI		T2T-CHM13v2.0

Dis3l2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	86,629,646 - 86,977,819 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	86,631,530 - 86,977,817 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	86,701,924 - 87,050,097 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	86,703,808 - 87,050,095 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	88,600,379 - 88,946,672 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	88,535,014 - 88,881,263 (+)	NCBI		MGSCv36	mm8
Celera	1	89,673,472 - 90,022,293 (+)	NCBI		Celera
Cytogenetic Map	1	C5	NCBI
cM Map	1	43.99	NCBI

Dis3l2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	94,802,056 - 95,184,523 (+)	NCBI		GRCr8
mRatBN7.2	9	87,355,409 - 87,736,616 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	87,356,457 - 87,736,616 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	95,772,927 - 96,160,932 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	100,901,251 - 101,296,662 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	99,284,763 - 99,664,872 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	93,767,837 - 94,161,106 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	93,660,680 - 94,160,760 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	93,495,138 - 93,886,547 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	85,470,810 - 85,855,679 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	9	84,770,512 - 85,150,470 (+)	NCBI		Celera
Cytogenetic Map	9	q35	NCBI

Dis3l2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	3,559,067 - 3,830,064 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955453	3,558,744 - 3,851,222 (-)	NCBI	ChiLan1.0	ChiLan1.0

DIS3L2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	134,559,408 - 134,928,324 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	134,574,474 - 134,943,290 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	119,187,659 - 119,558,347 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	237,976,038 - 238,346,098 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	238,030,931 - 238,347,570 (+)	Ensembl	panpan1.1		panPan2

DIS3L2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	43,754,382 - 44,099,497 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	43,754,484 - 44,095,381 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	44,247,553 - 44,594,062 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	44,010,739 - 44,357,418 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	44,010,802 - 44,353,289 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	43,937,826 - 44,283,331 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	43,781,874 - 44,128,602 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	43,936,863 - 44,283,235 (+)	NCBI		UU_Cfam_GSD_1.0

DIS3L2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	132,540,829 - 132,906,232 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	132,540,784 - 132,902,943 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	146,803,737 - 146,810,407 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DIS3L2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	117,959,396 - 118,350,728 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	117,960,326 - 118,352,176 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	81,041,213 - 81,483,661 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dis3l2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624843	4,901,316 - 5,196,827 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624843	4,900,810 - 5,196,827 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005326433	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727085	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727086	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040268002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040268003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040268004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040268005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040268006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040268007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040268008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040268009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040268010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040268011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040268012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005725906	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005725907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000005682 ⟹ ENSSTOP00000005085

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936525	4,719,121 - 5,008,014 (-)	Ensembl

RefSeq Acc Id:

XM_021727088 ⟹ XP_021582763

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,213 - 186,061,651 (+)	NCBI
SpeTri2.0	NW_004936525	4,878,087 - 5,008,357 (-)	NCBI

Sequence:

show sequence

GCTAAGCAAGTGCTCTACCACTGAGCCATTTGTGGAAATTTTTAATTGAAGTGTTCCAAAGGAG
CAGACTTGTGTACTCAGCACAGATGGTGTGCTTGATGGAGTGCTCAGGAAAATGTGACACCAGG
ACCCAAGAGGACACCATATTGCCTTTGCCATCCAACTGGTGACAACTGAGCTGCTTCAGACAGG
AAGAACTTTAAGCTGAGCAGTAGTGGCTCCCCTGAATCTGGAGAGAAGAGGAGCCCCTGGAACC
AGTAATGAGCCATCCTGACTACAGACTGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCC
TCTGTGGTTGGTCCCCATGGTTTTGGTGCTTCGCCAGGTGACAAAAAGTCGAAGAACAAGTCCA
CACGAGGGAAGAAAAGGAGCATATTTGAGACCTACATGTCCAAGGAGGCGGTTTCAGAAGGCTT
GAAGAGAGGAGCACTTATCCAGGGTGTACTGAGAATCAATCCAAAGAAGTTTCATGAAGCCTTC
ATTCCTTCCCCGGATGGTGATCGAGACATTTTTATCGATGGAGTTGTTGCTCGTAATAGAGCTT
TGAATGGGGATCTGGTGGTTGTGAAACTGCTTCCGGAGGAGCAGTGGAAGGTAATTAAGCCAGA
GAGCAATGACAAAGAAACAGAAGCTGCCTACGAGTCTGATCTCCCCGAGGAGCTCTGTGGACAC
CACCTCCCACAGCAGGCCTTAAAAGGCGATAATGATAGTCCTGATGTCATTATAGAGGCTCAAT
TTGGTGACAGTGACTCAGAAGATGGACATGGAGACACACAAAATGTGCTGGTTGATGGTGTTGA
GAAACTCTCAGTTCGCGCTCAGGACAAGGGAAAAGAGGATGCTAATGCACCAGTTACAAAAGAT
GAGAGCACCTCCATGTCACAAGACACAAAAGCTTTATCAGAGAAGTCCCTGCAGAAATCAGCTA
AGGTGGTTTACATCTTGGAGAAAAAACATTCCCGAGCAGCCACCGGCATCCTCAAACTGTTGGC
TGATAAGAACAGTGAGCTGTTTAGGAAATATGCCCTGTTTTCTCCCTCAGACCACCGAGTGCCT
AGAATTTATGTACCTCTCAAGGACTGTCCCCAGGACTTTGTGACCCGGCCTAAAGATTATGCCA
ACACATTGTTCATCTGCCGCATCGTGGACTGGAAGGAGGACAGCAATTTTGCGCTGGGGCAGCT
GGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAGCCTGAAACAGAAGGGATACTAACAGAGTAT
GGTGTAGATTTCTCTGATTTCTCCTCAGAAGTTCTAGAATGTCTCCCCCAAAGCCTGCCCTGGA
CAATTCCACCAGAGGAACTCAGCAAGAGAAGAGATTTAAGCGTGTCTACTAGCTGCAGATAAAT
ACTAAGCATTGCAGAAGTCACAGGGCCCAGCATTCCTCCAAGCTCCGCCCTACCATTTCTATGG
CCCTCATTGCCTTGGACTACAGAATTACAGAATATACAAGGCCTTACTCTGCAGAAAGCCTCTG
TTAAAGTCTACTGTGCTTGCTGTGGAGGGATGGAAAGGTAGAGGGACTTTAGGATGCTGTGTGC
CAACTAGTGGAGTAACAAGGATTTAAAAAAAAATAAAAAACA

hide sequence

RefSeq Acc Id:

XM_021727089 ⟹ XP_021582764

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,213 - 186,063,511 (+)	NCBI
SpeTri2.0	NW_004936525	4,876,671 - 5,008,357 (-)	NCBI

Sequence:

show sequence

GCTAAGCAAGTGCTCTACCACTGAGCCATTTGTGGAAATTTTTAATTGAAGTGTTCCAAAGGAG
CAGACTTGTGTACTCAGCACAGATGGTGTGCTTGATGGAGTGCTCAGGAAAATGTGACACCAGG
ACCCAAGAGGACACCATATTGCCTTTGCCATCCAACTGGTGACAACTGAGCTGCTTCAGACAGG
AAGAACTTTAAGCTGAGCAGTAGTGGCTCCCCTGAATCTGGAGAGAAGAGGAGCCCCTGGAACC
AGTAATGAGCCATCCTGACTACAGACTGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCC
TCTGTGGTTGGTCCCCATGGTTTTGGTGCTTCGCCAGGTGACAAAAAGTCGAAGAACAAGTCCA
CACGAGGGAAGAAAAGGAGCATATTTGAGACCTACATGTCCAAGGAGGCGGTTTCAGAAGGCTT
GAAGAGAGGAGCACTTATCCAGGGTGTACTGAGAATCAATCCAAAGAAGTTTCATGAAGCCTTC
ATTCCTTCCCCGGATGGTGATCGAGACATTTTTATCGATGGAGTTGTTGCTCGTAATAGAGCTT
TGAATGGGGATCTGGTGGTTGTGAAACTGCTTCCGGAGGAGCAGTGGAAGGTAATTAAGCCAGA
GAGCAATGACAAAGAAACAGAAGCTGCCTACGAGTCTGATCTCCCCGAGGAGCTCTGTGGACAC
CACCTCCCACAGCAGGCCTTAAAAGGCGATAATGATAGTCCTGATGTCATTATAGAGGCTCAAT
TTGGTGACAGTGACTCAGAAGATGGACATGGAGACACACAAAATGTGCTGGTTGATGGTGTTGA
GAAACTCTCAGTTCGCGCTCAGGACAAGGGAAAAGAGGATGCTAATGCACCAGTTACAAAAGAT
GAGAGCACCTCCATGTCACAAGACACAAAAGCTTTATCAGAGAAGTCCCTGCAGAAATCAGCTA
AGGTGGTTTACATCTTGGAGAAAAAACATTCCCGAGCAGCCACCGGCATCCTCAAACTGTTGGC
TGATAAGAACAGTGAGCTGTTTAGGAAATATGCCCTGTTTTCTCCCTCAGACCACCGAGTGCCT
AGAATTTATGTACCTCTCAAGGACTGTCCCCAGGACTTTGTGACCCGGCCTAAAGATTATGCCA
ACACATTGTTCATCTGCCGCATCGTGGACTGGAAGGAGGACAGCAATTTTGCGCTGGGGCAGCT
GGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAGCCTGAAACAGAAGGGATACTAACAGAGTAT
GGTGTAGATTTCTCTGATTTCTCCTCAGAAGTTCTAGAATGTCTCCCCCAAAGCCTGCCCTGGA
CAATTCCACCAGAGGAACTCAGCAAGAGAAGAGATTTAAGTGGGCTGAAAGCATAGGTACCAAG
GAGCGCTGAGGTCGTGTTCTGGAGTGCTGACTCATCTGCATGCCTCTCTTACCCTGTGGCCCAA
ACACCCAGTGAGGACACCAGAGTTAATTCATACGTTTGTATAGCTGTGTAGTCTTGATTAATTT
CTTACGTT

hide sequence

RefSeq Acc Id:

XM_021727090 ⟹ XP_021582765

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,213 - 186,059,181 (+)	NCBI
SpeTri2.0	NW_004936525	4,880,457 - 5,008,357 (-)	NCBI

Sequence:

show sequence

GCTAAGCAAGTGCTCTACCACTGAGCCATTTGTGGAAATTTTTAATTGAAGTGTTCCAAAGGAG
CAGACTTGTGTACTCAGCACAGATGGTGTGCTTGATGGAGTGCTCAGGAAAATGTGACACCAGG
ACCCAAGAGGACACCATATTGCCTTTGCCATCCAACTGGTGACAACTGAGCTGCTTCAGACAGG
AAGAACTTTAAGCTGAGCAGTAGTGGCTCCCCTGAATCTGGAGAGAAGAGGAGCCCCTGGAACC
AGTAATGAGCCATCCTGACTACAGACTGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCC
TCTGTGGTTGGTCCCCATGGTTTTGGTGCTTCGCCAGGTGACAAAAAGTCGAAGAACAAGTCCA
CACGAGGGAAGAAAAGGAGCATATTTGAGACCTACATGTCCAAGGAGGCGGTTTCAGAAGGCTT
GAAGAGAGGAGCACTTATCCAGGGTGTACTGAGAATCAATCCAAAGAAGTTTCATGAAGCCTTC
ATTCCTTCCCCGGATGGTGATCGAGACATTTTTATCGATGGAGTTGTTGCTCGTAATAGAGCTT
TGAATGGGGATCTGGTGGTTGTGAAACTGCTTCCGGAGGAGCAGTGGAAGGTAATTAAGCCAGA
GAGCAATGACAAAGAAACAGAAGCTGCCTACGAGTCTGATCTCCCCGAGGAGCTCTGTGGACAC
CACCTCCCACAGCAGGCCTTAAAAGGCGATAATGATAGTCCTGATGTCATTATAGAGGCTCAAT
TTGGTGACAGTGACTCAGAAGATGGACATGGAGACACACAAAATGTGCTGGTTGATGGTGTTGA
GAAACTCTCAGTTCGCGCTCAGGACAAGGGAAAAGAGGATGCTAATGCACCAGTTACAAAAGAT
GAGAGCACCTCCATGTCACAAGACACAAAAGCTTTATCAGAGAAGTCCCTGCAGAAATCAGCTA
AGGTGGTTTACATCTTGGAGAAAAAACATTCCCGAGCAGCCACCGGCATCCTCAAACTGTTGGC
TGATAAGAACAGTGAGCTGTTTAGGAAATATGCCCTGTTTTCTCCCTCAGACCACCGAGTGCCT
AGAATTTATGTACCTCTCAAGGACTGTCCCCAGGACTTTGTGACCCGGCCTAAAGATTATGCCA
ACACATTGTTCATCTGCCGCATCGTGGACTGGAAGGAGGACAGCAATTTTGCGCTGGGGTGTGG
GTCCAGTATCAGTGCTGGTTGCCTTTATGAGGTTTGCTGAGTTCTGGATCCACCATCTCTTGGC
AGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAGCCTGAAACAGAAGGGATACTAACAGA
GTATGGTGTAGATTTCTCTGATTTCTCCTCAGAAGTTCTAGAATGTCTCCCCCAAAGCCTGCCC
TGGACAATTCCACCAGAGGAACTCAGCAAGAGAAGAGATTTAAG

hide sequence

RefSeq Acc Id:

XM_040268002 ⟹ XP_040123936

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,213 - 186,220,572 (+)	NCBI

RefSeq Acc Id:

XM_040268003 ⟹ XP_040123937

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,929,064 - 186,220,572 (+)	NCBI

RefSeq Acc Id:

XM_040268004 ⟹ XP_040123938

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,165 - 186,220,572 (+)	NCBI

RefSeq Acc Id:

XM_040268005 ⟹ XP_040123939

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,379 - 186,220,572 (+)	NCBI

RefSeq Acc Id:

XM_040268006 ⟹ XP_040123940

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,213 - 186,220,572 (+)	NCBI

RefSeq Acc Id:

XM_040268007 ⟹ XP_040123941

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,929,062 - 186,220,572 (+)	NCBI

RefSeq Acc Id:

XM_040268008 ⟹ XP_040123942

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,379 - 186,220,572 (+)	NCBI

RefSeq Acc Id:

XM_040268009 ⟹ XP_040123943

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,379 - 186,220,572 (+)	NCBI

RefSeq Acc Id:

XM_040268010 ⟹ XP_040123944

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,213 - 186,220,945 (+)	NCBI

RefSeq Acc Id:

XM_040268011 ⟹ XP_040123945

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,213 - 186,217,788 (+)	NCBI

RefSeq Acc Id:

XM_040268012 ⟹ XP_040123946

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,213 - 186,061,651 (+)	NCBI

RefSeq Acc Id:

XR_005725906

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,213 - 186,191,618 (+)	NCBI

RefSeq Acc Id:

XR_005725907

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	185,881,213 - 186,144,345 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_021582763	(Get FASTA)	NCBI Sequence Viewer
	XP_021582764	(Get FASTA)	NCBI Sequence Viewer
	XP_021582765	(Get FASTA)	NCBI Sequence Viewer
	XP_040123936	(Get FASTA)	NCBI Sequence Viewer
	XP_040123937	(Get FASTA)	NCBI Sequence Viewer
	XP_040123938	(Get FASTA)	NCBI Sequence Viewer
	XP_040123939	(Get FASTA)	NCBI Sequence Viewer
	XP_040123940	(Get FASTA)	NCBI Sequence Viewer
	XP_040123941	(Get FASTA)	NCBI Sequence Viewer
	XP_040123942	(Get FASTA)	NCBI Sequence Viewer
	XP_040123943	(Get FASTA)	NCBI Sequence Viewer
	XP_040123944	(Get FASTA)	NCBI Sequence Viewer
	XP_040123945	(Get FASTA)	NCBI Sequence Viewer
	XP_040123946	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000005085.3
GenBank Protein	KAG3275507	(Get FASTA)	NCBI Sequence Viewer
	KAG3275508	(Get FASTA)	NCBI Sequence Viewer
	KAG3275509	(Get FASTA)	NCBI Sequence Viewer
	KAG3275510	(Get FASTA)	NCBI Sequence Viewer
	KAG3275511	(Get FASTA)	NCBI Sequence Viewer
	KAG3275512	(Get FASTA)	NCBI Sequence Viewer
	KAG3275513	(Get FASTA)	NCBI Sequence Viewer
	KAG3275514	(Get FASTA)	NCBI Sequence Viewer
	KAG3275515	(Get FASTA)	NCBI Sequence Viewer
	KAG3275516	(Get FASTA)	NCBI Sequence Viewer
	KAG3275517	(Get FASTA)	NCBI Sequence Viewer
	KAG3275518	(Get FASTA)	NCBI Sequence Viewer
	KAG3275519	(Get FASTA)	NCBI Sequence Viewer
	KAG3275520	(Get FASTA)	NCBI Sequence Viewer
	KAG3275521	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_021582764 ⟸ XM_021727089

- Peptide Label:

isoform X5

- Sequence:

show sequence

MSHPDYRLNLRPLGTPRGVSSVVGPHGFGASPGDKKSKNKSTRGKKRSIFETYMSKEAVSEGLK
RGALIQGVLRINPKKFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEQWKVIKPES
NDKETEAAYESDLPEELCGHHLPQQALKGDNDSPDVIIEAQFGDSDSEDGHGDTQNVLVDGVEK
LSVRAQDKGKEDANAPVTKDESTSMSQDTKALSEKSLQKSAKVVYILEKKHSRAATGILKLLAD
KNSELFRKYALFSPSDHRVPRIYVPLKDCPQDFVTRPKDYANTLFICRIVDWKEDSNFALGQLA
KSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQSLPWTIPPEELSKRRDLSGLKA

hide sequence

RefSeq Acc Id:

XP_021582763 ⟸ XM_021727088

- Peptide Label:

isoform X4

- Sequence:

show sequence

MSHPDYRLNLRPLGTPRGVSSVVGPHGFGASPGDKKSKNKSTRGKKRSIFETYMSKEAVSEGLK
RGALIQGVLRINPKKFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEQWKVIKPES
NDKETEAAYESDLPEELCGHHLPQQALKGDNDSPDVIIEAQFGDSDSEDGHGDTQNVLVDGVEK
LSVRAQDKGKEDANAPVTKDESTSMSQDTKALSEKSLQKSAKVVYILEKKHSRAATGILKLLAD
KNSELFRKYALFSPSDHRVPRIYVPLKDCPQDFVTRPKDYANTLFICRIVDWKEDSNFALGQLA
KSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQSLPWTIPPEELSKRRDLSVSTSCR

hide sequence

RefSeq Acc Id:

XP_021582765 ⟸ XM_021727090

- Peptide Label:

isoform X7

- Sequence:

show sequence

MSHPDYRLNLRPLGTPRGVSSVVGPHGFGASPGDKKSKNKSTRGKKRSIFETYMSKEAVSEGLK
RGALIQGVLRINPKKFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEQWKVIKPES
NDKETEAAYESDLPEELCGHHLPQQALKGDNDSPDVIIEAQFGDSDSEDGHGDTQNVLVDGVEK
LSVRAQDKGKEDANAPVTKDESTSMSQDTKALSEKSLQKSAKVVYILEKKHSRAATGILKLLAD
KNSELFRKYALFSPSDHRVPRIYVPLKDCPQDFVTRPKDYANTLFICRIVDWKEDSNFALGCGS
SISAGCLYEVC

hide sequence

RefSeq Acc Id:	XP_040123938 ⟸ XM_040268004
- Peptide Label:	isoform X1
- UniProtKB:	I3M6I1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040123944 ⟸ XM_040268010
- Peptide Label:	isoform X2
- UniProtKB:	I3M6I1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040123936 ⟸ XM_040268002
- Peptide Label:	isoform X1
- UniProtKB:	I3M6I1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040123940 ⟸ XM_040268006
- Peptide Label:	isoform X1
- UniProtKB:	I3M6I1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040123945 ⟸ XM_040268011
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_040123946 ⟸ XM_040268012
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_040123939 ⟸ XM_040268005
- Peptide Label:	isoform X1
- UniProtKB:	I3M6I1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040123942 ⟸ XM_040268008
- Peptide Label:	isoform X1
- UniProtKB:	I3M6I1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040123943 ⟸ XM_040268009
- Peptide Label:	isoform X1
- UniProtKB:	I3M6I1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040123941 ⟸ XM_040268007
- Peptide Label:	isoform X1
- UniProtKB:	I3M6I1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040123937 ⟸ XM_040268003
- Peptide Label:	isoform X1
- UniProtKB:	I3M6I1 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000005085 ⟸ ENSSTOT00000005682

Protein Domains

Ribonuclease II/R

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000005668	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000005682.3	UniProtKB/TrEMBL
Gene3D-CATH	2.40.50.140	UniProtKB/TrEMBL
	2.40.50.690	UniProtKB/TrEMBL
	2.40.50.700	UniProtKB/TrEMBL
InterPro	Dis3_CSD2	UniProtKB/TrEMBL
	DIS3L2	UniProtKB/TrEMBL
	Dis3l2_C	UniProtKB/TrEMBL
	NA-bd_OB-fold	UniProtKB/TrEMBL
	RNase_II/R	UniProtKB/TrEMBL
	RNase_II/R_CS	UniProtKB/TrEMBL
	Rrp44_CSD1	UniProtKB/TrEMBL
NCBI Gene	Dis3l2	ENTREZGENE
PANTHER	DIS3-LIKE EXONUCLEASE 2	UniProtKB/TrEMBL
	RIBONUCLEASE	UniProtKB/TrEMBL
Pfam	Dis3l2_C_term	UniProtKB/TrEMBL
	OB_Dis3	UniProtKB/TrEMBL
	RNB	UniProtKB/TrEMBL
	Rrp44_CSD1	UniProtKB/TrEMBL
PROSITE	RIBONUCLEASE_II	UniProtKB/TrEMBL
SMART	RNB	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50249	UniProtKB/TrEMBL
UniProt	I3M6I1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM