Fgr (FGR proto-oncogene, Src family tyrosine kinase) - Rat Genome Database
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Gene: Fgr (FGR proto-oncogene, Src family tyrosine kinase) Ictidomys tridecemlineatus
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Symbol: Fgr
Name: FGR proto-oncogene, Src family tyrosine kinase
RGD ID: 12584903
Description: ENCODES a protein that exhibits Fc-gamma receptor I complex binding (ortholog); immunoglobulin receptor binding (ortholog); non-membrane spanning protein tyrosine kinase activity (ortholog); INVOLVED IN bone mineralization (ortholog); defense response to Gram-positive bacterium (ortholog); integrin-mediated signaling pathway (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; glypican signaling pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN actin cytoskeleton (ortholog); aggresome (ortholog); cytoskeleton (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: feline Gardner-Rasheed sarcoma viral oncogene homolog; tyrosine-protein kinase Fgr
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647411,897,998 - 11,919,153 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
Fgr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647411,897,998 - 11,919,153 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl127,612,064 - 27,635,185 (-)EnsemblGRCh38hg38GRCh38
GRCh38127,612,064 - 27,635,561 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37127,938,575 - 27,961,696 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37127,938,800 - 27,961,727 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36127,811,387 - 27,834,314 (-)NCBINCBI36hg18NCBI36
Build 34127,622,952 - 27,634,715NCBI
Celera126,334,465 - 26,357,390 (-)NCBI
Cytogenetic Map1p35.3NCBI
HuRef126,195,016 - 26,217,930 (-)NCBIHuRef
CHM1_1128,054,060 - 28,076,993 (-)NCBICHM1_1
Fgr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394132,701,406 - 132,729,204 (+)NCBIGRCm39mm39
GRCm384132,974,095 - 133,001,893 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4132,974,095 - 133,001,910 (+)EnsemblGRCm38mm10GRCm38
MGSCv374132,530,010 - 132,557,808 (+)NCBIGRCm37mm9NCBIm37
MGSCv364132,246,204 - 132,273,882 (+)NCBImm8
Celera4131,136,566 - 131,164,622 (+)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map466.11NCBI
Fgr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25145,189,814 - 145,219,571 (+)NCBI
Rnor_6.0 Ensembl5151,172,206 - 151,199,745 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05151,172,189 - 151,199,746 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05154,839,086 - 154,866,424 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45152,119,455 - 152,147,057 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15152,129,494 - 152,157,096 (-)NCBI
Celera5143,612,003 - 143,639,441 (+)NCBICelera
RH 3.4 Map5977.8RGD
Cytogenetic Map5q36NCBI
Fgr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554526,841,802 - 6,863,542 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554526,840,274 - 6,863,460 (-)NCBIChiLan1.0ChiLan1.0
FGR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1127,918,758 - 27,941,678 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl127,918,758 - 27,941,678 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0126,872,781 - 26,895,751 (-)NCBIMhudiblu_PPA_v0panPan3
FGR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl272,680,675 - 72,690,251 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1272,678,858 - 72,692,417 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
FGR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl684,809,542 - 84,830,361 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1684,809,534 - 84,830,401 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2678,326,176 - 78,358,345 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGR
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120105,155,223 - 105,178,813 (+)NCBI
ChlSab1.1 Ensembl20105,165,043 - 105,179,067 (+)Ensembl
Fgr
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476411,482,719 - 11,513,215 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_013365089   ⟹   XP_013220543
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_00493647411,897,998 - 11,919,153 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013220543 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013220543   ⟸   XM_013365089
- UniProtKB: I3MV50 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Protein kinase   SH2   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000026717 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000015995 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000020771 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.30.505.10 UniProtKB/TrEMBL
InterPro Fgr_SH2 UniProtKB/TrEMBL
  Fyn/Yrk_SH3 UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/TrEMBL
NCBI Gene Fgr ENTREZGENE
Pfam Pkinase_Tyr UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
PRINTS SH2DOMAIN UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/TrEMBL
  TYRKINASE UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  TyrKc UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt I3MV50 ENTREZGENE, UniProtKB/TrEMBL