Acvr2b (activin A receptor type 2B) - Rat Genome Database

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Gene: Acvr2b (activin A receptor type 2B) Ictidomys tridecemlineatus
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Symbol: Acvr2b
Name: activin A receptor type 2B
RGD ID: 12582780
Description: ENCODES a protein that exhibits activin binding (ortholog); growth factor binding (ortholog); inhibin binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); activin receptor signaling pathway (ortholog); adrenal gland development (ortholog); PARTICIPATES IN activin signaling pathway; ASSOCIATED WITH Brugada syndrome (ortholog); situs inversus (ortholog); visceral heterotaxy (ortholog); FOUND IN cytoplasm (ortholog); protein-containing complex (ortholog); receptor complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: activin receptor type-2B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118194,654,498 - 194,692,968 (+)NCBI
SpeTri2.0NW_00493647327,816,366 - 27,822,555 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Acvr2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118194,654,498 - 194,692,968 (+)NCBI
SpeTri2.0NW_00493647327,816,366 - 27,822,555 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACVR2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl338,453,890 - 38,493,142 (+)EnsemblGRCh38hg38GRCh38
GRCh38338,453,890 - 38,493,142 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37338,495,381 - 38,534,633 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36338,470,794 - 38,509,637 (+)NCBINCBI36hg18NCBI36
Build 34338,470,813 - 38,499,868NCBI
Celera338,431,705 - 38,470,515 (+)NCBI
Cytogenetic Map3p22.2NCBI
HuRef338,561,058 - 38,576,879 (+)NCBIHuRef
CHM1_1338,447,458 - 38,486,272 (+)NCBICHM1_1
Acvr2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399119,231,081 - 119,271,214 (+)NCBIGRCm39mm39
GRCm39 Ensembl9119,231,184 - 119,264,061 (+)Ensembl
GRCm389119,401,583 - 119,442,148 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,402,118 - 119,434,995 (+)EnsemblGRCm38mm10GRCm38
MGSCv379119,311,619 - 119,342,633 (+)NCBIGRCm37mm9NCBIm37
MGSCv369119,251,199 - 119,282,213 (+)NCBImm8
Celera9119,872,378 - 119,903,791 (+)NCBICelera
Cytogenetic Map9F3NCBI
Acvr2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28119,138,901 - 119,178,477 (+)NCBI
Rnor_6.0 Ensembl8128,087,345 - 128,118,746 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08128,087,308 - 128,126,776 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08127,294,071 - 127,331,625 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48124,364,330 - 124,395,748 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18124,383,832 - 124,415,475 (+)NCBI
Celera8118,290,038 - 118,321,362 (+)NCBICelera
Cytogenetic Map8q32NCBI
Acvr2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542725,438,652 - 25,467,360 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542725,438,652 - 25,467,360 (-)NCBIChiLan1.0ChiLan1.0
ACVR2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1338,633,097 - 38,671,843 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl338,633,093 - 38,662,063 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0338,350,838 - 38,389,839 (+)NCBIMhudiblu_PPA_v0panPan3
ACVR2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1238,211,555 - 8,225,596 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl238,192,483 - 8,218,894 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha238,227,583 - 8,268,772 (+)NCBI
ROS_Cfam_1.0238,476,238 - 8,517,658 (+)NCBI
UMICH_Zoey_3.1238,290,311 - 8,331,505 (+)NCBI
UNSW_CanFamBas_1.0238,431,051 - 8,471,999 (+)NCBI
UU_Cfam_GSD_1.0238,424,247 - 8,465,433 (+)NCBI
ACVR2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1323,237,699 - 23,267,382 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11323,237,699 - 23,276,086 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21325,422,228 - 25,450,766 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACVR2B
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.115923,222 - 962,438 (-)NCBI
Acvr2b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247312,557,993 - 2,600,250 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005317374   ⟹   XP_005317431
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118194,654,503 - 194,692,968 (+)NCBI
SpeTri2.0NW_00493647327,816,366 - 27,822,555 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732262   ⟹   XP_021587937
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118194,654,498 - 194,692,968 (+)NCBI
SpeTri2.0NW_00493647327,816,366 - 27,822,555 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040290027   ⟹   XP_040145961
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118194,654,788 - 194,692,968 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005317431 (Get FASTA)   NCBI Sequence Viewer  
  XP_021587937 (Get FASTA)   NCBI Sequence Viewer  
  XP_040145961 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005317431   ⟸   XM_005317374
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021587937   ⟸   XM_021732262
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_040145961   ⟸   XM_040290027
- Peptide Label: isoform X3
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014862 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000013315 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014864 UniProtKB/TrEMBL
InterPro Activin_recp UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  TGFB_receptor UniProtKB/TrEMBL
NCBI Gene Acvr2b ENTREZGENE
PANTHER PTHR23255 UniProtKB/TrEMBL
Pfam Activin_recp UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PRINTS ACTIVIN2R UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt I3MNP8_ICTTR UniProtKB/TrEMBL