Mrm3 (mitochondrial rRNA methyltransferase 3)

Gene: Mrm3 (mitochondrial rRNA methyltransferase 3) Ictidomys tridecemlineatus

Analyze

Symbol:

Mrm3

Name:

mitochondrial rRNA methyltransferase 3

RGD ID:

12581220

Description:

ENCODES a protein that exhibits identical protein binding (inferred); RNA binding (inferred); RNA methyltransferase activity (inferred); INVOLVED IN RNA processing (inferred); rRNA 2'-O-methylation (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

mitochondrial rRNA methyltransferase 3, transcript variant X1; mitochondrial rRNA methyltransferase 3, transcript variant X2; rRNA methyltransferase 3, mitochondrial

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	44,120,525 - 44,126,162 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936538	6,998,472 - 7,004,086 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936538	6,998,472 - 7,004,109 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

RNA processing (IEA)

rRNA 2'-O-methylation (IEA)

Cellular Component

cytoplasm (IEA)

mitochondrion (IEA)

Molecular Function

identical protein binding (IEA)

protein binding (ISO)

RNA binding (IEA)

RNA methyltransferase activity (IEA)

rRNA (guanosine-2'-O-)-methyltransferase activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Mrm3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	44,120,525 - 44,126,162 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936538	6,998,472 - 7,004,086 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936538	6,998,472 - 7,004,109 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MRM3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	782,353 - 792,509 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	782,353 - 792,509 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	685,593 - 695,749 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	632,263 - 642,491 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	632,262 - 642,490	NCBI
Celera	17	697,654 - 707,881 (+)	NCBI		Celera
Cytogenetic Map	17	p13.3	NCBI
HuRef	17	596,108 - 606,167 (+)	NCBI		HuRef
CHM1_1	17	694,323 - 704,548 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	668,784 - 678,768 (+)	NCBI		T2T-CHM13v2.0

Mrm3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	76,134,562 - 76,141,451 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	76,134,541 - 76,141,445 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	76,243,736 - 76,250,625 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	76,243,715 - 76,250,619 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	76,057,238 - 76,064,124 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	76,059,965 - 76,066,817 (+)	NCBI		MGSCv36	mm8
Celera	11	83,756,564 - 83,763,458 (+)	NCBI		Celera
Cytogenetic Map	11	B5	NCBI
cM Map	11	45.92	NCBI

Mrm3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	61,594,155 - 61,623,659 (+)	NCBI		GRCr8
mRatBN7.2	10	61,095,920 - 61,125,421 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	61,095,952 - 61,102,630 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	65,738,499 - 65,745,175 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	65,243,947 - 65,250,623 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	60,714,294 - 60,720,972 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	64,398,308 - 64,406,193 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	64,398,339 - 64,405,017 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	63,609,355 - 63,616,033 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	63,600,163 - 63,600,936 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	63,613,778 - 63,614,559 (+)	NCBI
Celera	10	60,111,345 - 60,118,020 (+)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

Mrm3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955481	2,324,409 - 2,332,522 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955481	2,324,370 - 2,333,788 (+)	NCBI	ChiLan1.0	ChiLan1.0

MRM3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	22,794,447 - 22,795,438 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	71,119,171 - 71,120,162 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	18,615,903 - 18,616,894 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	17,920,413 - 17,942,602 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	672,895 - 682,795 (+)	Ensembl	panpan1.1		panPan2

MRM3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	45,004,382 - 45,011,834 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	45,005,145 - 45,011,811 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	44,154,903 - 44,162,361 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	45,822,471 - 45,829,938 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	45,822,475 - 45,829,925 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	44,601,216 - 44,608,659 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	44,894,820 - 44,902,487 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	44,973,562 - 44,981,019 (-)	NCBI		UU_Cfam_GSD_1.0

MRM3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	47,080,367 - 47,087,405 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	47,077,812 - 47,087,409 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	49,244,622 - 49,251,667 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MRM3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	40,183,052 - 40,185,655 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666042	64,342,413 - 64,343,242 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mrm3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624786	3,524,380 - 3,532,571 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624786	3,524,049 - 3,532,621 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005327880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021728144	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000016428 ⟹ ENSSTOP00000014703

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936538	6,998,472 - 7,004,086 (-)	Ensembl

RefSeq Acc Id:

XM_005327880 ⟹ XP_005327937

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	44,120,525 - 44,126,162 (-)	NCBI
SpeTri2.0	NW_004936538	6,998,472 - 7,004,109 (-)	NCBI

Sequence:

show sequence

GACGGCGCGCTTTCCTGACGTGACCCGCGGTACGGGAAAGATGGCGCTGCTGGTGAAGAACGTG
TGTTCTTCTGTGCGACCGTGGCTGCCAGTGGCCCAGACTTGGGATCTCAACGCGCGGCGCTGGG
TCCGGGCATTGCGGCGGAGCCCCTTGAAAGTGGTGTTTCCATCCGGAGAGGTGGTGGAGCGGAA
GCGCTCCCCTCGGAAGCAGCCCCGCGAGGCGGCGTCTGAGGCGCATGCCCAGGGGCAGCGACCG
AAACAGCCGCTTCAGATGTCCCCATCCCCTTCTCCGAGTACCTGGGAAGAGGCAGGACTTCGCT
ACGATAAAGCTTTTCCTGGGGATCGGAGGCTGAGCAGTGTAATGACAATAGTTAAGTCCAGGTC
GTTTCGGGACAAACAAGGGAAGATACTACTGGAAGGTCGCAGGCTGATTGCAGATGCTCTGAAG
GCTGGAGCTGTGCCAAAAGTTTTCTTCTTTAGCCGCCTGGAATACATAAAGGAGTTGCCAGTTG
ATAAGTTGAAAGGTGTAAGCCTCATTAAGGTGAAATTTGAGGATATCAAGGATTGGTCCGACCT
AGTAGCACCACAAGGAATAATTGGGATTTTTGCCAAACCTGACCATGTCAAAATGACATATCCA
GAGACTCAGCTTCAGCATTTCCTGCCCTTATTTTTGATTTGTGACAATCTCCGTGACCCTGGGA
ACCTGGGGACAATTCTGAGATCTGCTGCTGGGGCAGGCTGCAGCAAAGTATTACTAACTAAAGG
CTGTGTGGATGCCTGGGAACCCAAAGTGCTACGGGCAGGCATGGGGGCACATTTTCAGGTGCCT
ATTATCAATAATCTGGAATGGGAAACAGTACCCAATTACTTGCCCCCTGACACCCGGGTCCATG
TAGCAGACAACTGTGGCCTCTATGCTCAGGCCCAGATGTCTACTAAAGCCAGTGATTATGGCTG
GGTGTGTGATCGACGATTTCTGAAATTTCACAAGTTCCAGGAAGAGGATATAGAAACTGGAGAC
AGTAAAGACTGGCTTCCTGAAATTGAGGTTCAGAGTTATGACTTGGACTGGACAGAGGCACCAG
CAGCTGTGGTGATAGGTGGGGAGACCCATGGCGTGAGCCTGGAGTCCCTGCAGTTGGCTGAGAG
CACTGGGGGCAAGAGGCTGCTGATCCCTGTTGTGCCTGGTGTGGACAGCCTGAACTCGGCCATG
GCTGCAAGCATCCTGCTTTTTGAAGGAAAAAGACAGCTAAGGTTAAGGGTGGAACACTTGAACA
GGGACAGGACCTACCACTGAAAAAGGGGGCCGAAGTTGTGTTTGAGGATGCCTCCAGCTCCTGC
AACCCCAGCATACTGGATGGAGGCTGGCAGAGTTGGTTAACTGGCTTCCTGGCCATATTCAGGA
GGCAAGAGGTAGGCATTGCTGCCATCATACAGCGTCGGAAAAATAGGAATTTCTTAAGTTTCTG
CTTTTCCTCATAAATAAAAAGGTCAAAATTCTTCCTGA

hide sequence

RefSeq Acc Id:

XM_021728144 ⟹ XP_021583819

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	44,120,525 - 44,125,941 (-)	NCBI
SpeTri2.0	NW_004936538	6,998,472 - 7,003,817 (-)	NCBI

Sequence:

show sequence

AGTACCTGGGAAGAGGCAGGACTTCGCTACGATAAAGCTTTTCCTGGGGATCGGAGGCTGAGGG
ATTTTTGCCAAACCTGACCATGTCAAAATGACATATCCAGAGACTCAGCTTCAGCATTTCCTGC
CCTTATTTTTGATTTGTGACAATCTCCGTGACCCTGGGAACCTGGGGACAATTCTGAGATCTGC
TGCTGGGGCAGGCTGCAGCAAAGTATTACTAACTAAAGGCTGTGTGGATGCCTGGGAACCCAAA
GTGCTACGGGCAGGCATGGGGGCACATTTTCAGGTGCCTATTATCAATAATCTGGAATGGGAAA
CAGTACCCAATTACTTGCCCCCTGACACCCGGGTCCATGTAGCAGACAACTGTGGCCTCTATGC
TCAGGCCCAGATGTCTACTAAAGCCAGTGATTATGGCTGGGTGTGTGATCGACGATTTCTGAAA
TTTCACAAGTTCCAGGAAGAGGATATAGAAACTGGAGACAGTAAAGACTGGCTTCCTGAAATTG
AGGTTCAGAGTTATGACTTGGACTGGACAGAGGCACCAGCAGCTGTGGTGATAGGTGGGGAGAC
CCATGGCGTGAGCCTGGAGTCCCTGCAGTTGGCTGAGAGCACTGGGGGCAAGAGGCTGCTGATC
CCTGTTGTGCCTGGTGTGGACAGCCTGAACTCGGCCATGGCTGCAAGCATCCTGCTTTTTGAAG
GAAAAAGACAGCTAAGGTTAAGGGTGGAACACTTGAACAGGGACAGGACCTACCACTGAAAAAG
GGGGCCGAAGTTGTGTTTGAGGATGCCTCCAGCTCCTGCAACCCCAGCATACTGGATGGAGGCT
GGCAGAGTTGGTTAACTGGCTTCCTGGCCATATTCAGGAGGCAAGAGGTAGGCATTGCTGCCAT
CATACAGCGTCGGAAAAATAGGAATTTCTTAAGTTTCTGCTTTTCCTCATAAATAAAAAGGTCA
AAATTCTTCCTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005327937	(Get FASTA)	NCBI Sequence Viewer
	XP_021583819	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000014703.3
GenBank Protein	KAG3269699	(Get FASTA)	NCBI Sequence Viewer
	KAG3269700	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005327937 ⟸ XM_005327880
- Peptide Label:	isoform X1
- UniProtKB:	I3MRI3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MALLVKNVCSSVRPWLPVAQTWDLNARRWVRALRRSPLKVVFPSGEVVERKRSPRKQPREAASE AHAQGQRPKQPLQMSPSPSPSTWEEAGLRYDKAFPGDRRLSSVMTIVKSRSFRDKQGKILLEGR RLIADALKAGAVPKVFFFSRLEYIKELPVDKLKGVSLIKVKFEDIKDWSDLVAPQGIIGIFAKP DHVKMTYPETQLQHFLPLFLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAG MGAHFQVPIINNLEWETVPNYLPPDTRVHVADNCGLYAQAQMSTKASDYGWVCDRRFLKFHKFQ EEDIETGDSKDWLPEIEVQSYDLDWTEAPAAVVIGGETHGVSLESLQLAESTGGKRLLIPVVPG VDSLNSAMAASILLFEGKRQLRLRVEHLNRDRTYH hide sequence

RefSeq Acc Id:

XP_021583819 ⟸ XM_021728144

- Peptide Label:

isoform X2

- Sequence:

show sequence

MTYPETQLQHFLPLFLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAH
FQVPIINNLEWETVPNYLPPDTRVHVADNCGLYAQAQMSTKASDYGWVCDRRFLKFHKFQEEDI
ETGDSKDWLPEIEVQSYDLDWTEAPAAVVIGGETHGVSLESLQLAESTGGKRLLIPVVPGVDSL
NSAMAASILLFEGKRQLRLRVEHLNRDRTYH

hide sequence

RefSeq Acc Id:

ENSSTOP00000014703 ⟸ ENSSTOT00000016428

Protein Domains

RNA 2-O ribose methyltransferase substrate binding

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000016426	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000016428.3	UniProtKB/TrEMBL
Gene3D-CATH	3.30.1330.30	UniProtKB/TrEMBL
	3.40.1280.10	UniProtKB/TrEMBL
InterPro	Alpha/beta_knot_MTases	UniProtKB/TrEMBL
	L30e-like	UniProtKB/TrEMBL
	SpoU_MeTrfase	UniProtKB/TrEMBL
	SpoU_subst-bd	UniProtKB/TrEMBL
	tRNA_m1G_MTases_N	UniProtKB/TrEMBL
NCBI Gene	Mrm3	ENTREZGENE
PANTHER	RRNA METHYLTRANSFERASE 3	UniProtKB/TrEMBL
	RRNA METHYLTRANSFERASE 3, MITOCHONDRIAL	UniProtKB/TrEMBL
Pfam	SpoU_methylase	UniProtKB/TrEMBL
SMART	SpoU_sub_bind	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55315	UniProtKB/TrEMBL
	SSF75217	UniProtKB/TrEMBL
UniProt	I3MRI3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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