Lmo1 (LIM domain only 1) - Rat Genome Database

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Gene: Lmo1 (LIM domain only 1) Ictidomys tridecemlineatus
Analyze
Symbol: Lmo1
Name: LIM domain only 1
RGD ID: 12579176
Description: ENCODES a protein that exhibits DNA-binding transcription factor binding (inferred); metal ion binding (inferred); transcription coactivator activity (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); regulation of T cell homeostatic proliferation (ortholog); ASSOCIATED WITH genetic disease (ortholog); T-cell acute lymphoblastic leukemia (ortholog); FOUND IN nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LIM domain only 1, transcript variant X1; LIM domain only 1, transcript variant X2; LIM domain only 1, transcript variant X3; rhombotin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494753,626,372 - 53,713,474 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365289,707,677 - 9,747,468 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365289,707,683 - 9,747,449 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleolus  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Lmo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494753,626,372 - 53,713,474 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365289,707,677 - 9,747,468 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365289,707,683 - 9,747,449 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LMO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38118,224,309 - 8,268,787 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl118,224,309 - 8,268,716 (-)EnsemblGRCh38hg38GRCh38
GRCh37118,245,856 - 8,290,334 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36118,202,433 - 8,241,982 (-)NCBINCBI36Build 36hg18NCBI36
Build 34118,202,432 - 8,241,982NCBI
Celera118,363,953 - 8,403,488 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef117,913,914 - 7,958,156 (-)NCBIHuRef
CHM1_1118,244,701 - 8,288,993 (-)NCBICHM1_1
T2T-CHM13v2.0118,305,646 - 8,350,087 (-)NCBIT2T-CHM13v2.0
Lmo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397108,737,776 - 108,774,356 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7108,737,779 - 108,774,414 (-)EnsemblGRCm39 Ensembl
GRCm387109,138,565 - 109,175,207 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7109,138,572 - 109,175,207 (-)EnsemblGRCm38mm10GRCm38
MGSCv377116,282,086 - 116,313,822 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367108,929,748 - 108,961,690 (-)NCBIMGSCv36mm8
Celera7109,115,069 - 109,146,750 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map757.21NCBI
Lmo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81172,567,156 - 172,603,282 (-)NCBIGRCr8
mRatBN7.21163,132,338 - 163,168,521 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1163,132,339 - 163,168,522 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1171,473,978 - 171,509,933 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01178,660,040 - 178,695,995 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01171,332,980 - 171,368,943 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01173,728,183 - 173,764,288 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1173,728,184 - 173,764,250 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01180,718,642 - 180,753,931 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41166,706,025 - 166,741,550 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11166,817,032 - 166,852,213 (-)NCBI
Celera1161,038,350 - 161,074,053 (-)NCBICelera
Cytogenetic Map1q33NCBI
Lmo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541424,021,218 - 24,061,183 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541424,021,275 - 24,072,098 (-)NCBIChiLan1.0ChiLan1.0
LMO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2910,648,739 - 10,693,150 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11110,610,883 - 10,655,271 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0118,342,318 - 8,386,659 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1118,088,223 - 8,127,704 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl118,088,223 - 8,132,215 (-)Ensemblpanpan1.1panPan2
LMO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12131,727,723 - 31,780,179 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2131,727,242 - 31,763,645 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2131,296,487 - 31,348,744 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02132,601,145 - 32,653,395 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2132,601,145 - 32,641,571 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12131,870,976 - 31,923,201 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02132,036,918 - 32,089,231 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02132,330,836 - 32,383,167 (-)NCBIUU_Cfam_GSD_1.0
LMO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl91,076,938 - 1,082,974 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.191,045,138 - 1,082,974 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.291,248,307 - 1,282,660 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LMO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1156,533,530 - 56,578,167 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl156,571,860 - 56,577,855 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038154,259,090 - 154,304,334 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lmo1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624766392,953 - 431,015 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624766393,017 - 431,118 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000029933   ⟹   ENSSTOP00000016512
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365289,707,677 - 9,747,468 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000030776   ⟹   ENSSTOP00000031733
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365289,707,677 - 9,747,468 (+)Ensembl
RefSeq Acc Id: XM_005326832   ⟹   XP_005326889
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494753,677,862 - 53,713,474 (+)NCBI
SpeTri2.0NW_0049365289,711,864 - 9,747,449 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005326833   ⟹   XP_005326890
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494753,673,703 - 53,713,474 (+)NCBI
SpeTri2.0NW_0049365289,707,683 - 9,747,449 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021727385   ⟹   XP_021583060
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494753,673,697 - 53,713,474 (+)NCBI
SpeTri2.0NW_0049365289,707,686 - 9,747,449 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040284807   ⟹   XP_040140741
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494753,626,372 - 53,713,474 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005326890   ⟸   XM_005326833
- Peptide Label: isoform X2
- UniProtKB: A0A287DDW1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005326889   ⟸   XM_005326832
- Peptide Label: isoform X1
- UniProtKB: I3MWL7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021583060   ⟸   XM_021727385
- Peptide Label: isoform X1
- UniProtKB: I3MWL7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040140741   ⟸   XM_040284807
- Peptide Label: isoform X3
RefSeq Acc Id: ENSSTOP00000016512   ⟸   ENSSTOT00000029933
RefSeq Acc Id: ENSSTOP00000031733   ⟸   ENSSTOT00000030776
Protein Domains
LIM zinc-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000027480 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000029933.2 UniProtKB/TrEMBL
  ENSSTOT00000030776.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/TrEMBL
InterPro Znf_LIM UniProtKB/TrEMBL
NCBI Gene Lmo1 ENTREZGENE
PANTHER LD11652P UniProtKB/TrEMBL
  RHOMBOTIN-1 UniProtKB/TrEMBL
Pfam LIM UniProtKB/TrEMBL
PROSITE LIM_DOMAIN_1 UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/TrEMBL
SMART LIM UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt A0A287DDW1 ENTREZGENE, UniProtKB/TrEMBL
  I3MWL7 ENTREZGENE, UniProtKB/TrEMBL