Itga10 (integrin subunit alpha 10) - Rat Genome Database

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Gene: Itga10 (integrin subunit alpha 10) Ictidomys tridecemlineatus
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Symbol: Itga10
Name: integrin subunit alpha 10
RGD ID: 12578687
Description: ENCODES a protein that exhibits collagen binding involved in cell-matrix adhesion (inferred); integrin binding (inferred); metal ion binding (inferred); INVOLVED IN cell adhesion (inferred); cell adhesion mediated by integrin (inferred); cell-cell adhesion (inferred); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); osteochondrodysplasia (ortholog); FOUND IN external side of plasma membrane (inferred); integrin alpha10-beta1 complex (inferred); integrin complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: integrin alpha-10; integrin subunit alpha 10, transcript variant X1; integrin subunit alpha 10, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505820,760,844 - 20,776,865 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936867638,176 - 652,277 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936867636,981 - 652,642 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Itga10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505820,760,844 - 20,776,865 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936867638,176 - 652,277 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936867636,981 - 652,642 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITGA10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381145,891,208 - 145,910,050 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1145,891,208 - 145,910,111 (-)EnsemblGRCh38hg38GRCh38
GRCh371145,525,030 - 145,543,868 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361144,236,347 - 144,255,225 (+)NCBINCBI36Build 36hg18NCBI36
Build 341143,014,033 - 143,032,911NCBI
Celera1119,728,358 - 119,747,240 (+)NCBICelera
Cytogenetic Map1q21.1NCBI
HuRef1119,488,695 - 119,507,577 (+)NCBIHuRef
CHM1_11147,259,334 - 147,278,216 (-)NCBICHM1_1
T2T-CHM13v2.01145,008,042 - 145,026,867 (-)NCBIT2T-CHM13v2.0
Itga10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39396,552,900 - 96,571,835 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl396,552,900 - 96,571,835 (+)EnsemblGRCm39 Ensembl
GRCm38396,645,584 - 96,664,519 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl396,645,584 - 96,664,519 (+)EnsemblGRCm38mm10GRCm38
MGSCv37396,449,507 - 96,468,442 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36396,730,989 - 96,749,924 (+)NCBIMGSCv36mm8
MGSCv36396,949,167 - 96,969,343 (+)NCBIMGSCv36mm8
Celera398,052,591 - 98,071,470 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map341.93NCBI
Itga10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82186,871,711 - 186,891,012 (+)NCBIGRCr8
mRatBN7.22184,182,869 - 184,202,172 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2184,182,869 - 184,202,172 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2191,854,311 - 191,873,583 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02189,647,106 - 189,666,516 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02184,486,867 - 184,506,139 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02198,772,937 - 198,792,253 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2198,772,937 - 198,792,253 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02218,259,871 - 218,279,187 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42191,448,684 - 191,467,941 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12191,411,393 - 191,429,404 (+)NCBI
Celera2176,707,726 - 176,727,035 (+)NCBICelera
Cytogenetic Map2q34NCBI
Itga10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955568184,463 - 199,777 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955568184,399 - 201,329 (+)NCBIChiLan1.0ChiLan1.0
ITGA10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21103,282,925 - 103,305,457 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11102,869,042 - 102,893,819 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01121,847,420 - 121,866,560 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11113,803,019 - 113,821,908 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1113,803,019 - 113,821,908 (-)Ensemblpanpan1.1panPan2
ITGA10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11758,696,356 - 58,712,174 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1758,697,392 - 58,711,794 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1758,163,867 - 58,180,435 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01759,692,674 - 59,709,253 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1759,695,459 - 59,709,284 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11758,565,413 - 58,581,987 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01758,626,550 - 58,643,124 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01759,352,967 - 59,369,541 (-)NCBIUU_Cfam_GSD_1.0
ITGA10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl499,423,117 - 99,440,749 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1499,422,469 - 99,440,756 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24109,064,926 - 109,083,204 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103224063
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12012,835,551 - 12,854,342 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2012,827,633 - 12,835,517 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
ChlSab1.1 Ensembl2012,836,168 - 12,852,752 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603815,506,703 - 15,533,511 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Itga10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477217,255,598 - 17,269,669 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477217,253,972 - 17,269,796 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSSTOT00000013946   ⟹   ENSSTOP00000012497
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936867638,176 - 652,277 (-)Ensembl
RefSeq Acc Id: XM_005341315   ⟹   XP_005341372
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505820,760,844 - 20,776,865 (-)NCBI
SpeTri2.0NW_004936867636,981 - 652,642 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013365691   ⟹   XP_013221145
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505820,760,844 - 20,776,100 (-)NCBI
SpeTri2.0NW_004936867636,981 - 650,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040287470   ⟹   XP_040143404
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505820,760,844 - 20,776,865 (-)NCBI
RefSeq Acc Id: XM_040287471   ⟹   XP_040143405
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505820,760,844 - 20,776,865 (-)NCBI
RefSeq Acc Id: XM_040287472   ⟹   XP_040143406
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505820,760,844 - 20,776,865 (-)NCBI
RefSeq Acc Id: XM_040287473   ⟹   XP_040143407
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505820,763,834 - 20,776,865 (-)NCBI
RefSeq Acc Id: XP_005341372   ⟸   XM_005341315
- Peptide Label: isoform X1
- UniProtKB: I3MLZ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013221145   ⟸   XM_013365691
- Peptide Label: isoform X6
- UniProtKB: I3MLZ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040143406   ⟸   XM_040287472
- Peptide Label: isoform X4
- UniProtKB: I3MLZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040143404   ⟸   XM_040287470
- Peptide Label: isoform X2
- UniProtKB: I3MLZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040143405   ⟸   XM_040287471
- Peptide Label: isoform X3
- UniProtKB: I3MLZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040143407   ⟸   XM_040287473
- Peptide Label: isoform X5
- UniProtKB: I3MLZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000012497   ⟸   ENSSTOT00000013946
Protein Domains
VWFA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000013934 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000013946.3 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.130 UniProtKB/TrEMBL
  3.40.50.410 UniProtKB/TrEMBL
  Bicelle-embedded integrin alpha(iib) transmembrane segment UniProtKB/TrEMBL
  Integrin domains. Chain A, domain 2 UniProtKB/TrEMBL
  ntegrin, alpha v. Chain A, domain 3 UniProtKB/TrEMBL
  ntegrin, alpha v. Chain A, domain 4 UniProtKB/TrEMBL
InterPro FG-GAP UniProtKB/TrEMBL
  Int_alpha_beta-p UniProtKB/TrEMBL
  Integrin_alpha UniProtKB/TrEMBL
  Integrin_alpha-2 UniProtKB/TrEMBL
  Integrin_alpha_C_CS UniProtKB/TrEMBL
  Integrin_alpha_Ig-like_2 UniProtKB/TrEMBL
  Integrin_alpha_N UniProtKB/TrEMBL
  Integrin_dom_sf UniProtKB/TrEMBL
  VWF_A UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
NCBI Gene Itga10 ENTREZGENE
PANTHER INTEGRIN ALPHA UniProtKB/TrEMBL
  INTEGRIN ALPHA-10 UniProtKB/TrEMBL
Pfam FG-GAP UniProtKB/TrEMBL
  Integrin_A_Ig_2 UniProtKB/TrEMBL
  Integrin_alpha2 UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
PRINTS INTEGRINA UniProtKB/TrEMBL
  VWFADOMAIN UniProtKB/TrEMBL
PROSITE FG_GAP UniProtKB/TrEMBL
  INTEGRIN_ALPHA UniProtKB/TrEMBL
  VWFA UniProtKB/TrEMBL
SMART Int_alpha UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
Superfamily-SCOP SSF53300 UniProtKB/TrEMBL
  SSF69179 UniProtKB/TrEMBL
  SSF69318 UniProtKB/TrEMBL
UniProt I3MLZ8 ENTREZGENE, UniProtKB/TrEMBL