Acss3 (acyl-CoA synthetase short chain family member 3) - Rat Genome Database

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Gene: Acss3 (acyl-CoA synthetase short chain family member 3) Ictidomys tridecemlineatus
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Symbol: Acss3
Name: acyl-CoA synthetase short chain family member 3
RGD ID: 12578188
Description: ENCODES a protein that exhibits butyrate-CoA ligase activity (ortholog); INVOLVED IN lipid metabolic process (inferred); PARTICIPATES IN 3-hydroxyacyl-CoA dehydrogenase deficiency pathway; fatty acid beta degradation pathway; malonic aciduria pathway; ASSOCIATED WITH genetic disease (ortholog); FOUND IN intracellular membrane-bounded organelle (inferred); mitochondrial matrix (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acyl-CoA synthetase short chain family member 3, transcript variant X1; acyl-CoA synthetase short chain family member 3, transcript variant X2; acyl-CoA synthetase short-chain family member 3; acyl-CoA synthetase short-chain family member 3, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494536,823,381 - 36,982,797 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366981,929,683 - 2,089,228 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366981,929,683 - 2,089,703 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
Acss3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494536,823,381 - 36,982,797 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366981,929,683 - 2,089,228 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366981,929,683 - 2,089,703 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACSS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381281,077,871 - 81,261,210 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1280,936,414 - 81,261,210 (+)EnsemblGRCh38hg38GRCh38
GRCh371281,471,858 - 81,654,989 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361279,995,940 - 80,173,713 (+)NCBINCBI36Build 36hg18NCBI36
Celera1281,138,032 - 81,316,367 (+)NCBICelera
Cytogenetic Map12q21.31NCBI
HuRef1278,528,812 - 78,706,348 (+)NCBIHuRef
CHM1_11281,438,372 - 81,616,058 (+)NCBICHM1_1
T2T-CHM13v2.01281,056,837 - 81,240,187 (+)NCBIT2T-CHM13v2.0
Acss3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910106,769,375 - 106,959,622 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10106,769,378 - 106,959,529 (-)EnsemblGRCm39 Ensembl
GRCm3810106,933,514 - 107,123,761 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10106,933,517 - 107,123,668 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710106,373,220 - 106,560,720 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610106,369,192 - 106,527,778 (-)NCBIMGSCv36mm8
Celera10108,877,696 - 109,072,448 (-)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1055.66NCBI
Acss3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8744,127,725 - 44,336,707 (-)NCBIGRCr8
mRatBN7.2742,241,261 - 42,450,209 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl742,242,652 - 42,450,230 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx744,173,696 - 44,355,183 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0746,376,772 - 46,558,269 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0746,154,652 - 46,336,112 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0749,047,022 - 49,250,953 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl749,047,013 - 49,250,957 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0749,059,778 - 49,265,391 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4745,646,821 - 45,833,803 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1745,642,178 - 45,853,987 (-)NCBI
Celera739,145,557 - 39,324,519 (-)NCBICelera
Cytogenetic Map7q21NCBI
Acss3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540519,677,537 - 19,836,086 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540519,677,191 - 19,836,086 (+)NCBIChiLan1.0ChiLan1.0
ACSS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21089,115,744 - 89,300,534 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11289,110,389 - 89,291,091 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01278,586,987 - 78,771,478 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11281,698,782 - 81,878,325 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1281,698,875 - 81,878,325 (+)Ensemblpanpan1.1panPan2
ACSS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11523,337,386 - 23,480,766 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1523,338,432 - 23,478,593 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1523,761,776 - 23,904,041 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01523,699,143 - 23,842,034 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1523,699,019 - 23,841,651 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11523,276,355 - 23,427,464 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01523,336,248 - 23,478,319 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01523,576,616 - 23,719,097 (+)NCBIUU_Cfam_GSD_1.0
ACSS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5100,279,698 - 100,429,165 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.15100,272,255 - 100,429,229 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25105,195,329 - 105,368,501 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACSS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11176,563,595 - 76,737,014 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1176,563,668 - 76,736,852 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037168,686,420 - 168,867,257 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acss3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624837416,028 - 625,885 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624837416,779 - 626,097 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000013960   ⟹   ENSSTOP00000012510
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366981,929,683 - 2,089,228 (+)Ensembl
RefSeq Acc Id: XM_005337999   ⟹   XP_005338056
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494536,823,381 - 36,982,797 (-)NCBI
SpeTri2.0NW_0049366981,929,683 - 2,089,703 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040280270   ⟹   XP_040136204
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494536,823,381 - 36,960,186 (-)NCBI
RefSeq Acc Id: XM_040280271   ⟹   XP_040136205
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494536,823,381 - 36,958,450 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005338056 (Get FASTA)   NCBI Sequence Viewer  
  XP_040136204 (Get FASTA)   NCBI Sequence Viewer  
  XP_040136205 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000012510.3
GenBank Protein KAG3291312 (Get FASTA)   NCBI Sequence Viewer  
  KAG3291313 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005338056   ⟸   XM_005337999
- Peptide Label: isoform X1
- UniProtKB: I3MM09 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040136204   ⟸   XM_040280270
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040136205   ⟸   XM_040280271
- Peptide Label: isoform X3
RefSeq Acc Id: ENSSTOP00000012510   ⟸   ENSSTOT00000013960
Protein Domains
Acetyl-coenzyme A synthetase N-terminal   AMP-binding enzyme C-terminal   AMP-dependent synthetase/ligase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000013956 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000013960.3 UniProtKB/TrEMBL
Gene3D-CATH 3.30.300.30 UniProtKB/TrEMBL
  3.40.50.12780 UniProtKB/TrEMBL
InterPro ACAS_N UniProtKB/TrEMBL
  AMP-bd_C UniProtKB/TrEMBL
  AMP-bd_C_sf UniProtKB/TrEMBL
  AMP-binding_CS UniProtKB/TrEMBL
  AMP-dep_Synth/Lig UniProtKB/TrEMBL
  ANL_N_sf UniProtKB/TrEMBL
NCBI Gene Acss3 ENTREZGENE
PANTHER ACYL-COA SYNTHETASE UniProtKB/TrEMBL
  ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam ACAS_N UniProtKB/TrEMBL
  AMP-binding UniProtKB/TrEMBL
  AMP-binding_C UniProtKB/TrEMBL
PROSITE AMP_BINDING UniProtKB/TrEMBL
Superfamily-SCOP Acetyl-CoA synthetase-like UniProtKB/TrEMBL
UniProt I3MM09 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-20 Acss3  acyl-CoA synthetase short chain family member 3    acyl-CoA synthetase short-chain family member 3  Symbol and/or name change 5135510 APPROVED