Insyn2a (inhibitory synaptic factor 2A) - Rat Genome Database

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Gene: Insyn2a (inhibitory synaptic factor 2A) Ictidomys tridecemlineatus
Analyze
Symbol: Insyn2a
Name: inhibitory synaptic factor 2A
RGD ID: 12576071
Description: INVOLVED IN chemical synaptic transmission, postsynaptic (ortholog); ASSOCIATED WITH distal 10q deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN GABA-ergic synapse (ortholog); postsynaptic specialization (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Fam196a; family with sequence similarity 196 member A; Insyn2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721310,677,811 - 10,733,837 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648614,827,459 - 14,883,493 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648614,827,461 - 14,883,487 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Insyn2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721310,677,811 - 10,733,837 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648614,827,459 - 14,883,493 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648614,827,461 - 14,883,487 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INSYN2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810127,135,430 - 127,196,591 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10127,135,426 - 127,196,591 (-)EnsemblGRCh38hg38GRCh38
GRCh3710128,933,694 - 128,994,855 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610128,823,680 - 128,884,412 (-)NCBINCBI36Build 36hg18NCBI36
Celera10122,603,898 - 122,664,608 (-)NCBICelera
Cytogenetic Map10q26.2NCBI
HuRef10122,505,442 - 122,566,154 (-)NCBIHuRef
CHM1_110129,215,550 - 129,276,327 (-)NCBICHM1_1
T2T-CHM13v2.010128,029,007 - 128,090,188 (-)NCBIT2T-CHM13v2.0
Insyn2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397134,483,637 - 134,540,159 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7134,483,655 - 134,540,159 (-)EnsemblGRCm39 Ensembl
GRCm387134,881,908 - 134,938,430 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7134,881,926 - 134,938,430 (-)EnsemblGRCm38mm10GRCm38
MGSCv377142,073,591 - 142,130,113 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367134,737,378 - 134,776,773 (-)NCBIMGSCv36mm8
MGSCv367124,906,434 - 124,948,866 (-)NCBIMGSCv36mm8
Celera7134,696,154 - 134,753,000 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map780.86NCBI
Insyn2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81199,127,735 - 199,183,077 (-)NCBIGRCr8
mRatBN7.21189,697,856 - 189,753,194 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1189,697,878 - 189,752,922 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1198,057,120 - 198,112,181 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01205,217,998 - 205,273,027 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01197,891,501 - 197,946,530 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01207,116,698 - 207,171,885 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1207,116,717 - 207,171,760 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01214,053,082 - 214,108,141 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41194,506,981 - 194,563,096 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1187,414,267 - 187,469,308 (-)NCBICelera
Cytogenetic Map1q41NCBI
Insyn2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554774,945,431 - 5,003,408 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554774,945,431 - 5,003,381 (-)NCBIChiLan1.0ChiLan1.0
INSYN2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28139,006,465 - 139,067,094 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110139,011,815 - 139,072,889 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010123,716,226 - 123,777,268 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110127,972,818 - 128,033,414 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10127,972,818 - 128,033,414 (-)Ensemblpanpan1.1panPan2
INSYN2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12836,102,179 - 36,159,980 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2836,104,110 - 36,160,183 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2836,158,106 - 36,216,712 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02836,734,882 - 36,793,400 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2836,737,298 - 36,779,280 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12836,210,986 - 36,269,513 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02836,208,480 - 36,250,749 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02836,463,737 - 36,522,322 (-)NCBIUU_Cfam_GSD_1.0
INSYN2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14136,420,546 - 136,459,137 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114136,421,481 - 136,465,414 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214148,216,079 - 148,259,800 (+)NCBISscrofa10.2Sscrofa10.2susScr3
INSYN2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19119,748,966 - 119,810,394 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9119,748,993 - 119,810,042 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604881,126,892 - 81,188,233 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Insyn2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473719,827,461 - 19,885,070 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473719,826,903 - 19,884,494 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000008114   ⟹   ENSSTOP00000007266
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648614,827,459 - 14,883,493 (-)Ensembl
RefSeq Acc Id: XM_005320768   ⟹   XP_005320825
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721310,677,811 - 10,733,837 (+)NCBI
SpeTri2.0NW_00493648614,827,461 - 14,883,487 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021723381   ⟹   XP_021579056
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721310,678,830 - 10,733,837 (+)NCBI
SpeTri2.0NW_00493648614,827,461 - 14,872,012 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021723382   ⟹   XP_021579057
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721310,678,824 - 10,733,837 (+)NCBI
SpeTri2.0NW_00493648614,827,461 - 14,872,012 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040271764   ⟹   XP_040127698
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721310,693,556 - 10,733,837 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005320825   ⟸   XM_005320768
- Peptide Label: isoform X4
- UniProtKB: I3MB21 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021579057   ⟸   XM_021723382
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_021579056   ⟸   XM_021723381
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_040127698   ⟸   XM_040271764
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000007266   ⟸   ENSSTOT00000008114


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008121 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000008114.3 UniProtKB/TrEMBL
InterPro INSYN2 UniProtKB/TrEMBL
NCBI Gene Fam196a ENTREZGENE
PANTHER INHIBITORY SYNAPTIC FACTOR 2A UniProtKB/TrEMBL
  PTHR28682 UniProtKB/TrEMBL
Pfam FAM196 UniProtKB/TrEMBL
UniProt I3MB21 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 Insyn2a  inhibitory synaptic factor 2A  Insyn2    Symbol and/or name change 5135510 APPROVED
2018-05-29 Insyn2  inhibitory synaptic factor 2A  Fam196a  family with sequence similarity 196 member A  Symbol and/or name change 5135510 APPROVED