Zc3h18 (zinc finger CCCH-type containing 18) - Rat Genome Database

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Gene: Zc3h18 (zinc finger CCCH-type containing 18) Ictidomys tridecemlineatus
Analyze
Symbol: Zc3h18
Name: zinc finger CCCH-type containing 18
RGD ID: 12575712
Description: ENCODES a protein that exhibits metal ion binding (inferred); mRNA cap binding complex binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN RNA destabilization (inferred); ASSOCIATED WITH 16Q24.3 Microdeletion Syndrome (ortholog); autosomal recessive chronic granulomatous disease 4 (ortholog); genetic disease (ortholog); FOUND IN nuclear speck (inferred); precatalytic spliceosome (inferred); protein-containing complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc finger CCCH domain-containing protein 18; zinc finger CCCH-type containing 18, transcript variant X1; zinc finger CCCH-type containing 18, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934925,300,104 - 25,351,109 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366411,053,624 - 1,104,670 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366411,053,650 - 1,104,664 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Zc3h18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934925,300,104 - 25,351,109 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366411,053,624 - 1,104,670 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366411,053,650 - 1,104,664 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZC3H18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381688,570,403 - 88,631,964 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1688,570,403 - 88,631,964 (+)EnsemblGRCh38hg38GRCh38
GRCh371688,636,811 - 88,698,372 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,164,343 - 87,225,761 (+)NCBINCBI36Build 36hg18NCBI36
Celera1673,707,153 - 73,768,044 (+)NCBICelera
Cytogenetic Map16q24.2NCBI
HuRef1674,330,774 - 74,392,389 (+)NCBIHuRef
CHM1_11690,048,070 - 90,109,663 (+)NCBICHM1_1
T2T-CHM13v2.01694,638,009 - 94,699,796 (+)NCBIT2T-CHM13v2.0
Zc3h18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,103,298 - 123,144,104 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,103,348 - 123,144,099 (+)EnsemblGRCm39 Ensembl
GRCm388122,376,564 - 122,417,365 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8122,376,609 - 122,417,360 (+)EnsemblGRCm38mm10GRCm38
MGSCv378124,900,516 - 124,941,260 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368125,262,706 - 125,303,450 (+)NCBIMGSCv36mm8
Celera8126,605,738 - 126,646,471 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map870.98NCBI
Zc3h18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,344,422 - 67,388,400 (+)NCBIGRCr8
mRatBN7.21950,434,864 - 50,479,855 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1950,434,903 - 50,479,854 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1957,239,392 - 57,274,732 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01957,918,922 - 57,954,497 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,138,009 - 60,173,350 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,197,348 - 55,241,800 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,197,704 - 55,241,851 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01965,908,164 - 65,952,662 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,654,167 - 52,691,342 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11952,659,047 - 52,696,223 (+)NCBI
Celera1949,683,661 - 49,719,107 (+)NCBICelera
Cytogenetic Map19q12NCBI
Zc3h18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,524,499 - 2,567,203 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555412,531,230 - 2,566,959 (+)NCBIChiLan1.0ChiLan1.0
ZC3H18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21898,342,515 - 98,405,015 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,254,643 - 104,317,123 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01669,282,652 - 69,345,077 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11688,944,521 - 89,005,199 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1688,944,517 - 89,005,199 (+)Ensemblpanpan1.1panPan2
ZC3H18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1564,708,472 - 64,774,098 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl564,704,083 - 64,766,994 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha564,719,012 - 64,784,545 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0564,927,749 - 64,993,499 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,927,666 - 64,993,513 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,953,769 - 65,018,478 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,785,557 - 64,851,107 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0565,191,670 - 65,257,423 (-)NCBIUU_Cfam_GSD_1.0
ZC3H18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl61,030,418 - 1,081,538 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.161,030,416 - 1,081,541 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ZC3H18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1573,944,502 - 74,010,379 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl573,944,574 - 74,009,714 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660471,674,938 - 1,742,167 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zc3h18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746919,636 - 960,533 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624746923,734 - 964,965 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000023647   ⟹   ENSSTOP00000017773
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366411,054,284 - 1,096,745 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000032880   ⟹   ENSSTOP00000028582
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366411,053,624 - 1,104,670 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000033544   ⟹   ENSSTOP00000030515
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366411,053,624 - 1,104,670 (-)Ensembl
RefSeq Acc Id: XM_005335427   ⟹   XP_005335484
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934925,300,104 - 25,351,109 (-)NCBI
SpeTri2.0NW_0049366411,053,650 - 1,104,664 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040278880   ⟹   XP_040134814
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934925,300,104 - 25,351,109 (-)NCBI
RefSeq Acc Id: XM_040278881   ⟹   XP_040134815
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934925,300,104 - 25,351,109 (-)NCBI
RefSeq Acc Id: XM_040278882   ⟹   XP_040134816
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934925,300,104 - 25,351,108 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005335484   ⟸   XM_005335427
- Peptide Label: isoform X2
- UniProtKB: A0A287DAD0 (UniProtKB/TrEMBL),   A0A287D4Y2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040134814   ⟸   XM_040278880
- Peptide Label: isoform X1
- UniProtKB: A0A287D4Y2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134815   ⟸   XM_040278881
- Peptide Label: isoform X2
- UniProtKB: A0A287DAD0 (UniProtKB/TrEMBL),   A0A287D4Y2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134816   ⟸   XM_040278882
- Peptide Label: isoform X3
- UniProtKB: A0A287D4Y2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000028582   ⟸   ENSSTOT00000032880
RefSeq Acc Id: ENSSTOP00000030515   ⟸   ENSSTOT00000033544
RefSeq Acc Id: ENSSTOP00000017773   ⟸   ENSSTOT00000023647
Protein Domains
C3H1-type   E3 ligase CCCH-type zinc finger


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000022431 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000023647.2 UniProtKB/TrEMBL
  ENSSTOT00000032880.1 UniProtKB/TrEMBL
  ENSSTOT00000033544.1 UniProtKB/TrEMBL
Gene3D-CATH Zinc finger, CCCH-type UniProtKB/TrEMBL
InterPro Znf-CCCH_4 UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/TrEMBL
  Znf_CCCH_sf UniProtKB/TrEMBL
NCBI Gene Zc3h18 ENTREZGENE
PANTHER ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 UniProtKB/TrEMBL
  ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 UniProtKB/TrEMBL
Pfam zf-CCCH_4 UniProtKB/TrEMBL
PROSITE ZF_C3H1 UniProtKB/TrEMBL
SMART ZnF_C3H1 UniProtKB/TrEMBL
Superfamily-SCOP SSF90229 UniProtKB/TrEMBL
UniProt A0A287D4Y2 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DAD0 ENTREZGENE, UniProtKB/TrEMBL
  I3N077_ICTTR UniProtKB/TrEMBL