Izumo4 (IZUMO family member 4) - Rat Genome Database

Name: Izumo4
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Izumo4 (IZUMO family member 4) Ictidomys tridecemlineatus

Analyze

Symbol:

Izumo4

Name:

IZUMO family member 4

RGD ID:

12574666

Description:

ASSOCIATED WITH cyclic hematopoiesis (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

IZUMO family member 4, transcript variant X1; IZUMO family member 4, transcript variant X2; izumo sperm-egg fusion protein 4

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IZUMO4 (IZUMO family member 4)	NCBI	Ortholog
Mus musculus (house mouse):	Izumo4 (IZUMO family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Izumo4 (IZUMO family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Izumo4 (IZUMO family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IZUMO4 (IZUMO family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	IZUMO4 (IZUMO family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IZUMO4 (IZUMO family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IZUMO4 (IZUMO family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Izumo4 (IZUMO family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	216,612,343 - 216,614,796 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	1,219,866 - 1,222,455 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	1,220,013 - 1,223,767 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cyclic hematopoiesis (ISO)

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

progressive myoclonus epilepsy 9 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

nucleus (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Izumo4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	216,612,343 - 216,614,796 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	1,219,866 - 1,222,455 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	1,220,013 - 1,223,767 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IZUMO4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	2,096,915 - 2,099,590 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	2,096,429 - 2,099,593 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	2,096,914 - 2,099,589 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	2,047,868 - 2,050,583 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	2,047,867 - 2,050,583	NCBI
Celera	19	2,031,621 - 2,034,336 (+)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	1,869,152 - 1,871,867 (+)	NCBI		HuRef
CHM1_1	19	2,096,738 - 2,099,453 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	2,069,970 - 2,072,645 (+)	NCBI		T2T-CHM13v2.0

Izumo4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	80,537,858 - 80,541,216 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	80,538,018 - 80,541,207 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	80,702,015 - 80,705,382 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	80,702,184 - 80,705,373 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	80,165,438 - 80,168,127 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	80,105,313 - 80,108,501 (+)	NCBI		MGSCv36	mm8
Celera	10	81,721,074 - 81,723,763 (+)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Izumo4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	9,657,975 - 9,661,699 (-)	NCBI		GRCr8
mRatBN7.2	7	9,007,276 - 9,010,428 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,007,280 - 9,010,032 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	7	11,873,884 - 11,878,624 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	11,875,846 - 11,878,237 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	12,040,461 - 12,045,876 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	10,517,788 - 10,520,408 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	7	7,188,255 - 7,192,995 (-)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

Izumo4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	6,015,038 - 6,018,162 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	6,014,852 - 6,018,342 (-)	NCBI	ChiLan1.0	ChiLan1.0

IZUMO4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	6,478,657 - 6,481,419 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	5,709,421 - 5,712,172 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	1,106,258 - 1,109,009 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	2,080,204 - 2,082,944 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	2,080,205 - 2,082,944 (+)	Ensembl	panpan1.1		panPan2

IZUMO4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	56,933,644 - 56,936,171 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	56,933,646 - 56,936,163 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	56,728,630 - 56,731,174 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	57,666,470 - 57,669,014 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	57,666,472 - 57,668,989 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	56,718,417 - 56,720,963 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	57,203,579 - 57,206,117 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	57,404,033 - 57,406,580 (-)	NCBI		UU_Cfam_GSD_1.0

IZUMO4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	76,472,231 - 76,475,170 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	76,472,227 - 76,475,227 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	77,006,980 - 77,009,976 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IZUMO4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	1,897,533 - 1,900,266 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	1,897,573 - 1,900,295 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666081	6,840,401 - 6,843,139 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Izumo4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	6,751,884 - 6,754,688 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	6,751,736 - 6,754,746 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021730847	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021730848	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000020733 ⟹ ENSSTOP00000016657

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936588	1,219,866 - 1,222,455 (+)	Ensembl

RefSeq Acc Id:

XM_021730847 ⟹ XP_021586522

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	216,612,343 - 216,614,796 (-)	NCBI
SpeTri2.0	NW_004936588	1,220,013 - 1,223,767 (+)	NCBI

Sequence:

show sequence

GGCGGGGCGGGCCAGGCCATGGCCCTGCTGTTGTACCTGGGCATGACCGCGGCGCTGGCCCGCG
GCTGCCTGCACTGCCACGACAACTTCTCGGAGAAGTTCTCCTTCTATCGCCACCACGTAAACCT
CAAGTCCTGGTGGGTGGGCGACATCCCCGTTTCTGGGGCTCTGCTCACGGACTGGAGCGAAGAC
ACGATGAGGGAACTGCATTTGGCCATCCCGGCGGAGATCACCCGGGATAAGCTGAACCAAGTGG
CGGAAGCCGTGTACCAGAGGATGGATCAGCTGTACCAGGGGAAGATGTACTTCCCGGGGTATTT
CCCCAATGAGCTGCGAAGCATCTTCCGGGACCAGGTGCACCTCATCCAGAACGCAATCATTGAA
AGCCGCATTGATTGTCAGCGTCACTGTGGCATCTTCCAGTATGAGACCATCTCCTGCAATAACT
GCACAGACTCACATGTCATCTGCTTTGGCTACAACTGCGAGTCATCAGCACAGTGGGAGACAGC
CGTGCGTGGCCTTCTCAGTTACATAAATAATTGGCACAAACAGGACACCAACATGAGAACCACT
CCAGCCTTCCTGATATCACCAAGCTTCACGTGCCTGGAGCCACAGCACCTGGCCAACTTGACCT
TGGAAAATGCCTCGGAGTGTCTGACCCAGCACTGAGGGCCACCACCTTGCCCCCAGCTGCAGTG
GGGCAAAGGACTCAGCTGGACTGTCTCATTGTGCCTCTGACACAGGCTTGCTGCTGCCTCGGGT
CCCCCCAACCCCAGAGAGCCCAGGCTGGGCCAGGGTTGGGGGAAGGGAAGGGGGACGGGTTTGT
GTGTAGCACCAGCCCCTGGGCAGGGTCTCAGAGCTATTTGACAGGACGATTAAAGTTCCCTGAC
ATTTCTCATCCAAGAACAGTTCTTGCCCAGCAGGAGCCATTCAGAGGGCTTCTGGCCTCGTGTC
CATGGAGCCAGCGTCAGGTCCAGCGATTCCCAACAGCCCACTCTCCACTCCTGAACACTCGTGG
GCAGGCTCACAGGAAGGCACACCAAGGAAGCCATGGGTGCCTTCTGATAGCATAAGATGGGCCG
CACTGGGGGAGAGCCAGGCCAGCTTTACTTGCCTGGGGCTCTGGCCACAGCTCTGCCCCGAACT
CCAGCTGAGCTCAGAGGCCCTGGAAGGATGAAGGTGCTGCCCCCACATACCCACCCCCAGGGCA
CTCGCACAGGCACATTGCCTCTGACAACAGATGGACACAAGCCACTGTGGTCCCTGCTGCACCA
TTTCTCAGTGTCACACCACCTGCAACTGGGGGGGTAGACAGGCTCTGACTGCACCTCCGTGGGA
AGGGCAGGCTGCAGCAGGCGGAGGCGGTGGGCACACGTACCGCAGCTGCACAAGGCTGGCGGAG
TGCACACTCCTTTCTTGGGGTGGCTTCATTGCTCTGCACCCATGTGTGACAGCTCCTTTGCTCT
GCACCCGTGTGTGGCTGGCCTCGTGCGCAAGTGCCCCCAGGTGTGCTGGTGCTGTGCGCCGGCA
GGGCCTGCAACTCTAGAACGCATGCGGCTTATGTGTGGCAGCCTGTGGCGACTCCTCACCACCT
GCCTTCCAGAGCCATCGGGAATCATGCCACTTGAGCAGCTGGCCACCGAGCACGTTGTGTGGTT
ACCAACACTGAGCTTAAGGCTCCTTTGGGGGCCCCTTTGAGGGTCCTGACGGGGGCTGAAGTGG
ATGTCTGGAATCATGGGAAAGAGCCCACAGGTGGTGGCCGTTCAGACAGAGAGCCTGGACAAGA
AGCCAGTCCTGCTGTGGGTCACCTGCAGGACTGGGTCTGTACCAGAGTGAGGCCACTCGACTGT
CTGGTCCACGTGGTGCCAGTGTGGCCAACAAACGCCAGCCCCTTCCAGCCTGACCCTGGCCCTC
CCCACTGTGCCTCAACTGTGACTTCTAGGTGACAGCACTCCATGGGTAGAGGCTGGAGATTCCC
CCACCCACTACCGGCCCAGGCCCAGGAGCCGTGACTGCACGCTGGGGACCGTGGACACCTCTGC
AACCCCAACCTGGGTGCTGACCCTGGTGAAAGGCGTACAGAGGCCGGAGGAACGTGCAGAGTCT
GTTCTGCAACTTTATTGGATCATTTGGACACAAAATCATTACAGCAGCGTGATATGTCTATACG
GGAATGTCGATAGCAAATAGTCGTGTAACATCATACAATTTCAAAGTTCTAGAAT

hide sequence

Protein Sequences


Protein RefSeqs	XP_021586522	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000016657.1
GenBank Protein	KAG3280794	(Get FASTA)	NCBI Sequence Viewer
	KAG3280795	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_021586522 ⟸ XM_021730847

- UniProtKB:

I3MX12 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MALLLYLGMTAALARGCLHCHDNFSEKFSFYRHHVNLKSWWVGDIPVSGALLTDWSEDTMRELH
LAIPAEITRDKLNQVAEAVYQRMDQLYQGKMYFPGYFPNELRSIFRDQVHLIQNAIIESRIDCQ
RHCGIFQYETISCNNCTDSHVICFGYNCESSAQWETAVRGLLSYINNWHKQDTNMRTTPAFLIS
PSFTCLEPQHLANLTLENASECLTQH

hide sequence

RefSeq Acc Id:

ENSSTOP00000016657 ⟸ ENSSTOT00000020733

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000027805	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000020733.2	UniProtKB/TrEMBL
InterPro	IZUMO	UniProtKB/TrEMBL
NCBI Gene	Izumo4	ENTREZGENE
PANTHER	IZUMO SPERM-EGG FUSION PROTEIN 4	UniProtKB/TrEMBL
	IZUMO SPERM-EGG FUSION PROTEIN 4	UniProtKB/TrEMBL
Pfam	IZUMO	UniProtKB/TrEMBL
UniProt	I3MX12	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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