Adipoq (adiponectin, C1Q and collagen domain containing) - Rat Genome Database

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Gene: Adipoq (adiponectin, C1Q and collagen domain containing) Ictidomys tridecemlineatus
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Symbol: Adipoq
Name: adiponectin, C1Q and collagen domain containing
RGD ID: 12573460
Description: ENCODES a protein that exhibits hormone activity (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN brown fat cell differentiation (ortholog); cellular response to cAMP (ortholog); cellular response to drug (ortholog); PARTICIPATES IN adiponectin signaling pathway; ASSOCIATED WITH 3MC syndrome 1 (ortholog); Acute Lung Injury (ortholog); Alcoholic Fatty Liver (ortholog); FOUND IN cell surface (ortholog); endoplasmic reticulum (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: adiponectin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602117,076,470 - 117,087,548 (-)NCBI
SpeTri2.0NW_0049365783,168,599 - 3,179,369 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
3MC syndrome 1  (ISO)
Acute Lung Injury  (ISO)
Alcoholic Fatty Liver  (ISO)
Alzheimer's disease  (ISO)
amyloidosis  (ISO)
ankylosing spondylitis  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
autoimmune hepatitis  (ISO)
Behcet's disease  (ISO)
biliary atresia  (ISO)
bipolar disorder  (ISO)
brain infarction  (ISO)
breast cancer  (ISO)
cardiomyopathy  (ISO)
cardiovascular system disease  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Choroidal Neovascularization  (ISO)
Chronic Hepatitis C  (ISO)
chronic obstructive pulmonary disease  (ISO)
Cognitive Dysfunction  (ISO)
colitis  (ISO)
congestive heart failure  (ISO)
coronary aneurysm  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
coronary restenosis  (ISO)
Crohn's disease  (ISO)
dementia  (ISO)
diabetes mellitus  (ISO)
Diabetic Cardiomyopathies  (ISO)
Diabetic Foot  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
diffuse scleroderma  (ISO)
dry eye syndrome  (ISO)
end stage renal disease  (ISO)
Endotoxemia  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Myocarditis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
familial hyperlipidemia  (ISO)
familial Mediterranean fever  (ISO)
fatty liver disease  (ISO)
Fetal Growth Retardation  (ISO)
gestational diabetes  (ISO)
Graft vs Host Disease  (ISO)
Graves' disease  (ISO)
hepatocellular carcinoma  (ISO)
heroin dependence  (ISO)
HIV-Associated Lipodystrophy Syndrome  (ISO)
Human Viral Hepatitis  (ISO)
Huntington's disease  (ISO)
Hyperemia  (ISO)
hyperglycemia  (ISO)
hyperinsulinism  (ISO)
hypertension  (ISO)
hyperthyroidism  (ISO)
Hypertriglyceridemia  (ISO)
Hypoadiponectinemia  (ISO)
Inflammation  (ISO)
inflammatory bowel disease  (ISO)
Insulin Resistance  (ISO)
Jaundice  (ISO)
Kawasaki disease  (ISO)
Kidney Reperfusion Injury  (ISO)
Left Ventricular Hypertrophy  (ISO)
liver cirrhosis  (ISO)
Liver Reperfusion Injury  (ISO)
Mammary Neoplasms, Experimental  (ISO)
Masked Hypertension  (ISO)
Metabolic Syndrome  (ISO)
multiple sclerosis  (ISO)
Mycobacterium avium complex disease  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
myocarditis  (ISO)
non-alcoholic fatty liver disease  (ISO)
obesity  (ISO)
Oxygen-Induced Retinopathy  (ISO)
Perennial Allergic Rhinitis  (ISO)
peripheral artery disease  (ISO)
polycystic ovary syndrome  (ISO)
primary open angle glaucoma  (ISO)
proliferative diabetic retinopathy  (ISO)
prostate adenocarcinoma  (ISO)
pulmonary edema  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary tuberculosis  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
Rett syndrome  (ISO)
rheumatoid arthritis  (ISO)
Sepsis  (ISO)
sleep apnea  (ISO)
Spinal Cord Injuries  (ISO)
Stroke  (ISO)
Subarachnoid Hemorrhage  (ISO)
systemic lupus erythematosus  (ISO)
tongue squamous cell carcinoma  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
vascular disease  (ISO)
visual epilepsy  (ISO)
Weight Gain  (ISO)
Weight Loss  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
brown fat cell differentiation  (ISO)
cellular response to cAMP  (ISO)
cellular response to drug  (ISO)
cellular response to epinephrine stimulus  (ISO)
cellular response to insulin stimulus  (ISO)
circadian rhythm  (ISO)
detection of oxidative stress  (ISO)
fatty acid beta-oxidation  (ISO)
fatty acid oxidation  (ISO)
gene expression  (ISO)
glucose homeostasis  (ISO)
glucose metabolic process  (ISO)
low-density lipoprotein particle clearance  (ISO)
negative regulation of blood pressure  (ISO)
negative regulation of cell migration  (ISO)
negative regulation of cold-induced thermogenesis  (ISO)
negative regulation of DNA biosynthetic process  (ISO)
negative regulation of ERK1 and ERK2 cascade  (ISO)
negative regulation of fat cell differentiation  (ISO)
negative regulation of gluconeogenesis  (ISO)
negative regulation of granulocyte differentiation  (ISO)
negative regulation of heterotypic cell-cell adhesion  (ISO)
negative regulation of hormone secretion  (ISO)
negative regulation of I-kappaB kinase/NF-kappaB signaling  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of intracellular protein transport  (ISO)
negative regulation of low-density lipoprotein receptor activity  (ISO)
negative regulation of macrophage derived foam cell differentiation  (ISO)
negative regulation of macrophage differentiation  (ISO)
negative regulation of MAP kinase activity  (ISO)
negative regulation of metanephric mesenchymal cell migration  (ISO)
negative regulation of phagocytosis  (ISO)
negative regulation of platelet-derived growth factor receptor signaling pathway  (ISO)
negative regulation of platelet-derived growth factor receptor-alpha signaling pathway  (ISO)
negative regulation of protein autophosphorylation  (ISO)
negative regulation of receptor binding  (ISO)
negative regulation of synaptic transmission  (ISO)
negative regulation of transcription, DNA-templated  (ISO)
negative regulation of tumor necrosis factor production  (ISO)
negative regulation of tumor necrosis factor-mediated signaling pathway  (ISO)
negative regulation of vascular associated smooth muscle cell migration  (ISO)
negative regulation of vascular associated smooth muscle cell proliferation  (ISO)
positive regulation of cAMP-dependent protein kinase activity  (ISO)
positive regulation of cholesterol efflux  (ISO)
positive regulation of cold-induced thermogenesis  (ISO)
positive regulation of fatty acid metabolic process  (ISO)
positive regulation of glucose import  (ISO)
positive regulation of glycogen (starch) synthase activity  (ISO)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (ISO)
positive regulation of interleukin-8 production  (ISO)
positive regulation of lipid transporter activity  (ISO)
positive regulation of metanephric glomerular visceral epithelial cell development  (ISO)
positive regulation of monocyte chemotactic protein-1 production  (ISO)
positive regulation of myeloid cell apoptotic process  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of protein kinase A signaling  (ISO)
positive regulation of protein kinase activity  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of renal albumin absorption  (ISO)
positive regulation of signal transduction  (ISO)
protein localization to plasma membrane  (ISO)
regulation of glucose metabolic process  (ISO)
response to activity  (ISO)
response to bacterium  (ISO)
response to drug  (ISO)
response to ethanol  (ISO)
response to glucocorticoid  (ISO)
response to glucose  (ISO)
response to hypoxia  (ISO)
response to linoleic acid  (ISO)
response to nutrient  (ISO)
response to nutrient levels  (ISO)
response to sucrose  (ISO)
response to tumor necrosis factor  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Adipoq
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602117,076,470 - 117,087,548 (-)NCBI
SpeTri2.0NW_0049365783,168,599 - 3,179,369 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADIPOQ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3186,842,704 - 186,858,463 (+)EnsemblGRCh38hg38GRCh38
GRCh383186,842,710 - 186,858,463 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373186,560,499 - 186,576,252 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363188,043,157 - 188,058,946 (+)NCBINCBI36hg18NCBI36
Build 343188,043,164 - 188,058,952NCBI
Celera3184,996,682 - 185,012,474 (+)NCBI
Cytogenetic Map3q27.3NCBI
HuRef3183,969,546 - 183,985,186 (+)NCBIHuRef
CHM1_13186,523,992 - 186,539,778 (+)NCBICHM1_1
Adipoq
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391622,965,286 - 22,976,718 (+)NCBIGRCm39mm39
GRCm39 Ensembl1622,965,286 - 22,976,778 (+)Ensembl
GRCm381623,146,536 - 23,157,968 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1623,146,536 - 23,158,028 (+)EnsemblGRCm38mm10GRCm38
MGSCv371623,146,609 - 23,158,041 (+)NCBIGRCm37mm9NCBIm37
MGSCv361623,061,870 - 23,073,302 (+)NCBImm8
Celera1623,704,853 - 23,716,285 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1613.96NCBI
Adipoq
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21177,721,912 - 77,735,644 (-)NCBI
Rnor_6.0 Ensembl1181,330,293 - 81,344,488 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01181,330,845 - 81,344,488 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01184,363,940 - 84,382,663 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41179,908,291 - 79,911,065 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11179,965,888 - 79,968,654 (-)NCBI
Celera1176,596,543 - 76,599,824 (-)NCBICelera
Cytogenetic Map11q23NCBI
Adipoq
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542020,912,348 - 20,914,402 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542020,911,181 - 20,922,992 (-)NCBIChiLan1.0ChiLan1.0
ADIPOQ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13192,341,471 - 192,354,885 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3192,341,320 - 192,354,885 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03183,876,051 - 183,889,723 (+)NCBIMhudiblu_PPA_v0panPan3
ADIPOQ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13419,398,310 - 19,410,519 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3419,354,825 - 19,409,844 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3423,492,088 - 23,493,907 (+)NCBI
ROS_Cfam_1.03419,309,590 - 19,321,861 (+)NCBI
UMICH_Zoey_3.13419,349,075 - 19,350,894 (+)NCBI
UNSW_CanFamBas_1.03419,348,981 - 19,350,799 (+)NCBI
UU_Cfam_GSD_1.03419,582,218 - 19,584,037 (+)NCBI
ADIPOQ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13124,633,684 - 124,646,648 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113124,633,906 - 124,646,237 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213134,076,753 - 134,077,342 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADIPOQ
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11581,128,427 - 81,142,779 (+)NCBI
ChlSab1.1 Ensembl1581,129,795 - 81,147,391 (+)Ensembl
Adipoq
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473069,941,963 - 69,959,266 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005330993   ⟹   XP_005331050
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602117,076,470 - 117,087,548 (-)NCBI
SpeTri2.0NW_0049365783,168,599 - 3,179,369 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005330994   ⟹   XP_005331051
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602117,076,470 - 117,087,175 (-)NCBI
SpeTri2.0NW_0049365783,168,599 - 3,179,092 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013361046   ⟹   XP_013216500
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365783,168,599 - 3,171,928 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005331050 (Get FASTA)   NCBI Sequence Viewer  
  XP_005331051 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005331050   ⟸   XM_005330993
- UniProtKB: I3MQS1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005331051   ⟸   XM_005330994
- UniProtKB: I3MQS1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013216500   ⟸   XM_013361046
- Peptide Label: isoform X1
- Sequence:
Protein Domains
C1q


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000016020 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000014336 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000016020 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.40 UniProtKB/TrEMBL
InterPro Adiponectin UniProtKB/TrEMBL
  C1q_dom UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
  Tumour_necrosis_fac-like_dom UniProtKB/TrEMBL
NCBI Gene Adipoq ENTREZGENE
PANTHER PTHR15427:SF20 UniProtKB/TrEMBL
Pfam C1q UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
PRINTS COMPLEMNTC1Q UniProtKB/TrEMBL
PROSITE C1Q UniProtKB/TrEMBL
SMART C1Q UniProtKB/TrEMBL
Superfamily-SCOP SSF49842 UniProtKB/TrEMBL
UniProt I3MQS1 ENTREZGENE, UniProtKB/TrEMBL