Itih6 (inter-alpha-trypsin inhibitor heavy chain family member 6) - Rat Genome Database

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Gene: Itih6 (inter-alpha-trypsin inhibitor heavy chain family member 6) Ictidomys tridecemlineatus
Analyze
Symbol: Itih6
Name: inter-alpha-trypsin inhibitor heavy chain family member 6
RGD ID: 12571263
Description: ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN hyaluronan metabolic process (inferred); ASSOCIATED WITH autistic disorder (ortholog); Cornelia de Lange syndrome 2 (ortholog); Dwarfism (ortholog); FOUND IN extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inter-alpha-trypsin inhibitor heavy chain H6
RGD Orthologs
Human
Mouse
Rat
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X39,261,045 - 39,290,415 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367511,601,650 - 1,630,115 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367511,601,650 - 1,630,115 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Itih6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X39,261,045 - 39,290,415 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367511,601,650 - 1,630,115 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367511,601,650 - 1,630,115 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITIH6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X54,748,918 - 54,798,255 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX54,748,918 - 54,798,255 (-)EnsemblGRCh38hg38GRCh38
GRCh37X54,775,351 - 54,824,688 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X54,792,341 - 54,841,398 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X54,658,636 - 54,707,694NCBI
CeleraX58,607,891 - 58,657,233 (-)NCBICelera
Cytogenetic MapXp11.22NCBI
HuRefX51,825,181 - 51,875,088 (-)NCBIHuRef
CHM1_1X54,765,887 - 54,815,229 (-)NCBICHM1_1
T2T-CHM13v2.0X54,039,799 - 54,089,136 (-)NCBIT2T-CHM13v2.0
Itih6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X149,609,892 - 149,640,732 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX149,609,968 - 149,639,936 (+)EnsemblGRCm39 Ensembl
GRCm38X150,826,917 - 150,857,407 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX150,826,972 - 150,857,053 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X147,261,515 - 147,291,486 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X146,168,406 - 146,197,659 (+)NCBIMGSCv36mm8
CeleraX133,542,671 - 133,582,356 (-)NCBICelera
Cytogenetic MapXF3NCBI
cM MapX68.46NCBI
Itih6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X23,180,659 - 23,217,716 (+)NCBIGRCr8
mRatBN7.2X19,753,322 - 19,790,381 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX19,753,625 - 19,789,500 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0533,156,706 - 33,169,849 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
RGSC_v3.4X40,076,102 - 40,114,077 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX20,013,333 - 20,049,465 (+)NCBICelera
Cytogenetic MapXq12NCBI
ITIH6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X56,142,974 - 56,186,143 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X56,146,579 - 56,189,748 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X46,957,480 - 47,000,642 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X55,188,633 - 55,231,778 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX55,188,633 - 55,231,778 (-)Ensemblpanpan1.1panPan2
ITIH6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X47,537,909 - 47,584,419 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X53,231,323 - 53,349,651 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ITIH6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X50,847,762 - 50,889,414 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX50,848,078 - 50,888,786 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660864,815,426 - 4,855,911 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Itih6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462491054,671 - 70,773 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005339787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000022906   ⟹   ENSSTOP00000016789
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367511,601,650 - 1,630,115 (-)Ensembl
RefSeq Acc Id: XM_005339787   ⟹   XP_005339844
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X39,261,045 - 39,290,415 (-)NCBI
SpeTri2.0NW_0049367511,601,650 - 1,630,115 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005339844 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000016789.2
GenBank Protein KAG3272200 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005339844   ⟸   XM_005339787
- UniProtKB: I3MXE4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000016789   ⟸   ENSSTOT00000022906
Protein Domains
VIT   VWFA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000026991 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000022906.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/TrEMBL
InterPro ITI_HC_C UniProtKB/TrEMBL
  VIT UniProtKB/TrEMBL
  VWF_A UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
NCBI Gene Itih6 ENTREZGENE
PANTHER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER UniProtKB/TrEMBL
  INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H6 UniProtKB/TrEMBL
Pfam ITI_HC_C UniProtKB/TrEMBL
  VIT UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
PROSITE VIT UniProtKB/TrEMBL
  VWFA UniProtKB/TrEMBL
SMART VIT UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
Superfamily-SCOP SSF53300 UniProtKB/TrEMBL
UniProt I3MXE4 ENTREZGENE, UniProtKB/TrEMBL