Sh3tc2 (SH3 domain and tetratricopeptide repeats 2) - Rat Genome Database

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Gene: Sh3tc2 (SH3 domain and tetratricopeptide repeats 2) Ictidomys tridecemlineatus
Analyze
Symbol: Sh3tc2
Name: SH3 domain and tetratricopeptide repeats 2
RGD ID: 12571074
Description: INVOLVED IN myelination in peripheral nervous system (ortholog); peripheral nervous system myelin maintenance (ortholog); regulation of ERBB signaling pathway (ortholog); ASSOCIATED WITH arthrogryposis multiplex congenita (ortholog); autosomal dominant distal hereditary motor neuronopathy 14 (ortholog); Charcot-Marie-Tooth disease (ortholog); FOUND IN cytoplasmic vesicle (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SH3 domain and tetratricopeptide repeat-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213144,189,964 - 144,245,205 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365045,763,984 - 5,871,143 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365045,763,929 - 5,817,309 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Sh3tc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213144,189,964 - 144,245,205 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365045,763,984 - 5,871,143 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365045,763,929 - 5,817,309 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH3TC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385148,982,150 - 149,063,062 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5148,923,639 - 149,063,163 (-)EnsemblGRCh38hg38GRCh38
GRCh375148,361,713 - 148,442,625 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365148,341,906 - 148,422,930 (-)NCBINCBI36Build 36hg18NCBI36
Build 345148,364,376 - 148,422,880NCBI
Celera5144,443,778 - 144,524,792 (-)NCBICelera
Cytogenetic Map5q32NCBI
HuRef5143,506,997 - 143,588,011 (-)NCBIHuRef
CHM1_15147,794,201 - 147,875,232 (-)NCBICHM1_1
T2T-CHM13v2.05149,516,997 - 149,597,907 (-)NCBIT2T-CHM13v2.0
Sh3tc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391862,086,002 - 62,148,790 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1862,086,146 - 62,157,473 (+)EnsemblGRCm39 Ensembl
GRCm381861,952,928 - 62,015,719 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1861,953,075 - 62,024,402 (+)EnsemblGRCm38mm10GRCm38
MGSCv371862,112,729 - 62,175,373 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361862,078,453 - 62,141,084 (+)NCBIMGSCv36mm8
Celera1863,238,842 - 63,301,641 (+)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1834.78NCBI
Sh3tc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81857,686,701 - 57,747,735 (+)NCBIGRCr8
mRatBN7.21855,416,383 - 55,477,419 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1855,416,413 - 55,483,083 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01857,286,266 - 57,403,926 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1857,286,322 - 57,347,577 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01856,514,111 - 56,575,127 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41857,941,970 - 58,002,846 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11857,990,670 - 58,074,424 (+)NCBI
Celera1853,565,072 - 53,680,040 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Sh3tc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554155,303,311 - 5,355,672 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554155,286,475 - 5,354,880 (+)NCBIChiLan1.0ChiLan1.0
SH3TC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24144,216,609 - 144,294,434 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15142,356,158 - 142,433,983 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05144,412,449 - 144,490,183 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15150,439,183 - 150,498,467 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5150,438,976 - 150,498,354 (-)Ensemblpanpan1.1panPan2
SH3TC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1459,801,240 - 59,905,759 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl459,801,384 - 59,903,135 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha459,565,747 - 59,670,219 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0460,283,914 - 60,388,188 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl460,283,947 - 60,386,310 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1460,070,432 - 60,174,629 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0460,184,842 - 60,295,228 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0460,715,252 - 60,819,526 (+)NCBIUU_Cfam_GSD_1.0
SH3TC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2150,183,485 - 150,247,637 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12150,183,480 - 150,247,747 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22156,973,044 - 157,004,306 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SH3TC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12351,615,754 - 51,677,650 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603426,070,743 - 26,139,032 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sh3tc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247748,398,925 - 8,454,774 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247748,391,285 - 8,454,828 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000015093   ⟹   ENSSTOP00000013526
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365045,763,984 - 5,871,143 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000041434   ⟹   ENSSTOP00000026168
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365045,763,984 - 5,819,174 (+)Ensembl
RefSeq Acc Id: XM_021725694   ⟹   XP_021581369
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213144,189,965 - 144,245,205 (+)NCBI
SpeTri2.0NW_0049365045,763,929 - 5,817,309 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040272148   ⟹   XP_040128082
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213144,189,964 - 144,245,205 (+)NCBI
RefSeq Acc Id: XM_040272149   ⟹   XP_040128083
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213144,189,964 - 144,241,871 (+)NCBI
RefSeq Acc Id: XM_040272150   ⟹   XP_040128084
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213144,210,951 - 144,245,205 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021581369 (Get FASTA)   NCBI Sequence Viewer  
  XP_040128082 (Get FASTA)   NCBI Sequence Viewer  
  XP_040128083 (Get FASTA)   NCBI Sequence Viewer  
  XP_040128084 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000013526.3
  ENSSTOP00000026168.1
GenBank Protein KAG3266006 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021581369   ⟸   XM_021725694
- Peptide Label: isoform X2
- UniProtKB: A0A287CY14 (UniProtKB/TrEMBL),   I3MP54 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040128082   ⟸   XM_040272148
- Peptide Label: isoform X1
- UniProtKB: I3MP54 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040128083   ⟸   XM_040272149
- Peptide Label: isoform X3
- UniProtKB: I3MP54 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040128084   ⟸   XM_040272150
- Peptide Label: isoform X4
RefSeq Acc Id: ENSSTOP00000026168   ⟸   ENSSTOT00000041434
RefSeq Acc Id: ENSSTOP00000013526   ⟸   ENSSTOT00000015093
Protein Domains
SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015087 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015093.3 UniProtKB/TrEMBL
  ENSSTOT00000041434.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  SH3TC1/SH3TC2 UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
NCBI Gene Sh3tc2 ENTREZGENE
PANTHER PTHR22647 UniProtKB/TrEMBL
  SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam SH3_1 UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/TrEMBL
SMART SH3 UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A287CY14 ENTREZGENE, UniProtKB/TrEMBL
  I3MP54 ENTREZGENE, UniProtKB/TrEMBL