Rimklb (ribosomal modification protein rimK like family member B) - Rat Genome Database

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Gene: Rimklb (ribosomal modification protein rimK like family member B) Ictidomys tridecemlineatus
Analyze
Symbol: Rimklb
Name: ribosomal modification protein rimK like family member B
RGD ID: 12569977
Description: ENCODES a protein that exhibits ATP binding (inferred); citrate-L-glutamate ligase activity (inferred); metal ion binding (inferred); INVOLVED IN protein modification process (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy 21 (ortholog); genetic disease (ortholog); Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: beta-citrylglutamate synthase B; ribosomal modification protein rimK like family member B, transcript variant X1; ribosomal modification protein rimK like family member B, transcript variant X2; ribosomal modification protein rimK like family member B, transcript variant X3; ribosomal modification protein rimK like family member B, transcript variant X4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494598,595,524 - 98,678,455 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493687093,012 - 164,930 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493687093,084 - 175,154 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rimklb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494598,595,524 - 98,678,455 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493687093,012 - 164,930 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493687093,084 - 175,154 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIMKLB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38128,668,638 - 8,783,091 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl128,681,600 - 8,783,095 (+)EnsemblGRCh38hg38GRCh38
GRCh37128,834,196 - 8,935,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36128,741,785 - 8,821,054 (+)NCBINCBI36Build 36hg18NCBI36
Celera1210,388,117 - 10,467,384 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef128,632,397 - 8,711,651 (+)NCBIHuRef
CHM1_1128,819,474 - 8,898,746 (+)NCBICHM1_1
T2T-CHM13v2.0128,647,354 - 8,766,437 (+)NCBIT2T-CHM13v2.0
Rimklb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396122,424,255 - 122,464,021 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6122,424,255 - 122,475,720 (-)EnsemblGRCm39 Ensembl
GRCm386122,447,296 - 122,487,062 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6122,447,296 - 122,498,761 (-)EnsemblGRCm38mm10GRCm38
MGSCv376122,403,627 - 122,436,323 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366122,419,882 - 122,461,454 (-)NCBIMGSCv36mm8
Celera6124,249,271 - 124,268,350 (-)NCBICelera
Cytogenetic Map6F1NCBI
cM Map657.55NCBI
Rimklb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84157,336,950 - 157,396,970 (-)NCBIGRCr8
mRatBN7.24155,664,392 - 155,706,888 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4155,664,375 - 155,706,711 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.04155,258,241 - 155,292,809 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4155,260,103 - 155,275,161 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04222,283,614 - 222,318,109 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44158,904,485 - 158,950,642 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4144,485,390 - 144,527,333 (-)NCBICelera
Cytogenetic Map4q42NCBI
Rimklb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554136,306,414 - 6,346,278 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554136,298,833 - 6,362,812 (-)NCBIChiLan1.0ChiLan1.0
RIMKLB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21014,207,022 - 14,310,950 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11214,182,783 - 14,310,422 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0128,752,509 - 8,869,226 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1128,980,325 - 9,083,140 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl128,999,423 - 9,077,179 (+)Ensemblpanpan1.1panPan2
RIMKLB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12736,924,323 - 37,092,351 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2736,931,987 - 36,993,355 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha279,521,882 - 9,691,711 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02737,284,276 - 37,342,572 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2737,274,242 - 37,342,643 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12737,154,586 - 37,324,605 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02737,189,538 - 37,359,893 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0279,008,449 - 9,179,531 (+)NCBIUU_Cfam_GSD_1.0
RIMKLB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl562,676,225 - 62,715,067 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1562,676,220 - 62,715,273 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2565,508,345 - 65,623,232 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RIMKLB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1118,521,612 - 8,608,928 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl118,524,187 - 8,602,622 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666089592,545 - 696,961 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rimklb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248604,811,449 - 4,844,431 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248604,811,449 - 4,861,470 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000013145   ⟹   ENSSTOP00000011783
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493687093,012 - 164,930 (+)Ensembl
RefSeq Acc Id: XM_021720864   ⟹   XP_021576539
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494598,605,156 - 98,678,455 (-)NCBI
SpeTri2.0NW_00493687093,084 - 175,154 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005731926
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494598,595,524 - 98,644,208 (-)NCBI
RefSeq Acc Id: XR_005731927
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494598,595,524 - 98,678,277 (-)NCBI
RefSeq Acc Id: XR_005731928
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494598,595,524 - 98,644,208 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021576539 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000011783.3
GenBank Protein KAG3292432 (Get FASTA)   NCBI Sequence Viewer  
  KAG3292433 (Get FASTA)   NCBI Sequence Viewer  
  KAG3292434 (Get FASTA)   NCBI Sequence Viewer  
  KAG3292435 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021576539   ⟸   XM_021720864
- UniProtKB: I3MKG9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000011783   ⟸   ENSSTOT00000013145
Protein Domains
ATP-grasp


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000013154 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000013145.3 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1490.20 UniProtKB/TrEMBL
  3.40.50.20 UniProtKB/TrEMBL
  ATP-grasp fold, B domain UniProtKB/TrEMBL
InterPro ATP-grasp UniProtKB/TrEMBL
  ATP-grasp_RimK-type UniProtKB/TrEMBL
  ATP_grasp_subdomain_1 UniProtKB/TrEMBL
  RpS6_RimK/Lys_biosynth_LsyX UniProtKB/TrEMBL
NCBI Gene Rimklb ENTREZGENE
PANTHER BETA-CITRYLGLUTAMATE SYNTHASE B UniProtKB/TrEMBL
  RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN UniProtKB/TrEMBL
Pfam RimK UniProtKB/TrEMBL
PROSITE ATP_GRASP UniProtKB/TrEMBL
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/TrEMBL
UniProt I3MKG9 ENTREZGENE, UniProtKB/TrEMBL