LOC101961588 (cytochrome P450 2D17)

Gene: LOC101961588 (cytochrome P450 2D17) Ictidomys tridecemlineatus

Analyze

Symbol:

LOC101961588

Name:

cytochrome P450 2D17

RGD ID:

12566634

Description:

ENCODES a protein that exhibits anandamide 11,12 epoxidase activity (ortholog); anandamide 14,15 epoxidase activity (ortholog); anandamide 8,9 epoxidase activity (ortholog); INVOLVED IN alkaloid catabolic process (ortholog); alkaloid metabolic process (ortholog); arachidonic acid metabolic process (ortholog); PARTICIPATES IN celecoxib pharmacodynamics pathway; celecoxib pharmacokinetics pathway; citalopram pharmacodynamics pathway; ASSOCIATED WITH acute kidney failure (ortholog); acute lymphoblastic leukemia (ortholog); acute myeloid leukemia (ortholog); FOUND IN mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

cytochrome P450 2D17-like; cytochrome P450 2D4-like; cytochrome P450 2D4-like, transcript variant X1; cytochrome P450 2D4-like, transcript variant X2; cytochrome P450 2D6; LOC106145311; LOC110599497; uncharacterized LOC106145311; uncharacterized LOC110599497

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	6,804,025 - 6,843,868 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936718	153,340 - 157,966 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute kidney failure (ISO)

acute lymphoblastic leukemia (ISO)

acute myeloid leukemia (ISO)

alcohol dependence (ISO)

Alzheimer's disease (ISO)

amphetamine abuse (ISO)

asthma (ISO)

autism spectrum disorder (ISO)

autoimmune hepatitis (ISO)

basal ganglia disease (ISO)

Bradycardia (ISO)

Breast Neoplasms (ISO)

Chemical and Drug Induced Liver Injury (ISO)

Chronic Hepatitis C (ISO)

cognitive disorder (ISO)

Coma (ISO)

common variable immunodeficiency 4 (ISO)

Developmental Delay with Variable Intellectual Impairment and Behavioral Abnormalities (ISO)

Drug Overdose (ISO)

Drug-Induced Dyskinesia (ISO)

Dysmenorrhea (ISO)

dystonia (ISO)

epilepsy with generalized tonic-clonic seizures (ISO)

Experimental Liver Cirrhosis (ISO)

extrapyramidal and movement disease (ISO)

genetic disease (ISO)

head and neck squamous cell carcinoma (ISO)

intellectual disability (ISO)

interstitial nephritis (ISO)

major depressive disorder (ISO)

Manganese Poisoning (ISO)

multiple myeloma (ISO)

Muscle Rigidity (ISO)

Occupational Diseases (ISO)

opiate dependence (ISO)

Parkinson's disease (ISO)

Poor Drug Metabolism, CYP2D6-Related (ISO)

Prenatal Exposure Delayed Effects (ISO)

Prostatic Neoplasms (ISO)

rhinitis (ISO)

sexual health disorder (ISO)

substance-related disorder (ISO)

traumatic brain injury (ISO)

Tremor (ISO)

Weight Gain (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

alkaloid catabolic process (ISO)

alkaloid metabolic process (ISO)

arachidonic acid metabolic process (IEA,ISO)

C21-steroid hormone metabolic process (ISO)

coumarin metabolic process (ISO)

dopamine biosynthetic process (ISO)

dopamine metabolic process (ISO)

estrogen metabolic process (ISO)

female pregnancy (ISO)

isoquinoline alkaloid metabolic process (ISO)

monoterpenoid metabolic process (ISO)

negative regulation of cellular organofluorine metabolic process (ISO)

oxidative demethylation (ISO)

response to toluene (ISO)

retinol metabolic process (ISO)

serotonin biosynthetic process from tryptophan (ISO)

steroid metabolic process (ISO)

xenobiotic catabolic process (ISO)

xenobiotic metabolic process (IEA,ISO)

Cellular Component

cytoplasm (IEA)

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (IEA)

intracellular membrane-bounded organelle (IEA)

mitochondrion (ISO)

Molecular Function

anandamide 11,12 epoxidase activity (ISO)

anandamide 14,15 epoxidase activity (ISO)

anandamide 8,9 epoxidase activity (ISO)

arachidonic acid monooxygenase activity (ISO)

heme binding (IEA)

iron ion binding (IEA)

metal ion binding (IEA)

monooxygenase activity (IEA,ISO)

oxidoreductase activity (ISO)

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (IEA)

progesterone 21-hydroxylase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

celecoxib pharmacodynamics pathway (ISO)

celecoxib pharmacokinetics pathway (ISO)

citalopram pharmacodynamics pathway (ISO)

citalopram pharmacokinetics pathway (ISO)

clomipramine pharmacokinetics pathway (ISO)

codeine and morphine pharmacodynamics pathway (ISO)

codeine and morphine pharmacokinetics pathway (ISO)

desipramine pharmacodynamics pathway (ISO)

desipramine pharmacokinetics pathway (ISO)

doxepin pharmacokinetics pathway (ISO)

fluoxetine pharmacodynamics pathway (ISO)

fluoxetine pharmacokinetics pathway (ISO)

gefitinib pharmacokinetics pathway (ISO)

imipramine pharmacodynamics pathway (ISO)

imipramine pharmacokinetics pathway (ISO)

methadone pharmacodynamics pathway (ISO)

methadone pharmacokinetics pathway (ISO)

neviparine pharmacokinetics pathway (ISO)

paracetamol pharmacokinetics pathway (ISO)

statin pharmacokinetics pathway (ISO)

tamoxifen pharmacodynamics pathway (ISO)

tamoxifen pharmacokinetics pathway (ISO)

tramadol pharmacokinetics pathway (ISO)

venlafaxine pharmacokinetics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LOC101961588
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	6,804,025 - 6,843,868 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936718	153,340 - 157,966 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CYP2D6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	42,126,499 - 42,130,810 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	42,126,499 - 42,130,865 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	42,522,501 - 42,526,812 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	40,852,445 - 40,856,827 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	22	40,847,000 - 40,851,379	NCBI
Celera	22	26,328,694 - 26,333,076 (-)	NCBI		Celera
Cytogenetic Map	22	q13.2	NCBI
HuRef	22	25,488,519 - 25,492,901 (-)	NCBI		HuRef
CHM1_1	22	42,482,242 - 42,486,624 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	22	42,605,990 - 42,610,301 (-)	NCBI		T2T-CHM13v2.0

Cyp2d22
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	82,254,728 - 82,264,461 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	82,254,728 - 82,264,461 (-)	Ensembl		GRCm39 Ensembl
GRCm38	15	82,370,527 - 82,380,260 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	82,370,527 - 82,380,260 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	82,200,957 - 82,210,690 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	82,199,236 - 82,207,926 (-)	NCBI		MGSCv36	mm8
Celera	15	84,494,227 - 84,513,082 (-)	NCBI		Celera
Cytogenetic Map	15	E1	NCBI
cM Map	15	38.57	NCBI

Cyp2d4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	115,762,662 - 115,771,832 (-)	NCBI		GRCr8
mRatBN7.2	7	113,882,584 - 113,891,754 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	113,881,618 - 113,891,759 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	115,638,375 - 115,646,935 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	117,861,892 - 117,871,066 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	117,831,341 - 117,840,516 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	123,599,264 - 123,608,436 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	123,599,266 - 123,608,436 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	123,583,983 - 123,593,008 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	120,742,273 - 120,752,274 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	120,775,536 - 120,786,502 (-)	NCBI
Celera	7	110,197,422 - 110,206,650 (-)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

LOC100988273
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	51,959,870 - 51,969,146 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	54,654,160 - 54,664,840 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	23,022,449 - 23,031,627 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

CYP2D15
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	23,255,259 - 23,259,380 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	23,255,249 - 23,259,298 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	23,190,268 - 23,194,223 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	24,000,262 - 24,004,211 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	24,000,212 - 24,004,212 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	23,717,484 - 23,721,432 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	24,037,966 - 24,041,898 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	24,212,712 - 24,216,661 (+)	NCBI		UU_Cfam_GSD_1.0

CYP2D6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	6,538,907 - 6,543,642 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	6,539,021 - 6,543,643 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	3,810,426 - 3,815,068 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CYP2D6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	24,667,207 - 24,672,580 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	24,667,282 - 24,671,513 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	100,727,530 - 100,732,209 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021735449	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021735451	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277149	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277156	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277158	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277163	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277167	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277174	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277178	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277182	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_021735449 ⟹ XP_021591124

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,822,113 - 6,827,523 (+)	NCBI
SpeTri2.0	NW_004936718	153,340 - 157,961 (-)	NCBI

Sequence:

show sequence

AATCCCCAGTACCCTCCGACACCCAGGGTCAGGGAGAGTCTGGTGGATCACAGTGGAGGGAACC
CAGGACGAAGAGAGATGGGTGGAGGGTGAAGCCAAGGTGGACCAGTAGTTGTGCAGTGAAAGGA
AGCAGGCTGAGAGGTGTCCTGGTTGATGGCACGGCAGACAGAGCCCGAGGACCCTTTCAACTTT
CCAAGGGCAAAGGTGTGAGAGGACAAAGGCCAGGAGGTGGGACTGGACTTGGCAGTGGGTTTGG
GATCCAGGTGGGCAGGTATAAATTGAATAGGCCCCAGTCCCTTGTGATTCCATCAGAGGGAAAG
GTCTTGGGGATGGGGGAGGAGCCATAAGAGCTTGTCAGTCAGGAACTGAAGGTGGACACAGATT
GACAGACCCACTTAAAATTTTCTGCTGTGGGTCTTGCGCCTCACTGCTCACCTGTGTGACCGTG
TCTTCTGCTCTGTACAGTGGAGCACTATTGTCCCCATTGACGATATCCTGATTGGCAAGGTCAT
AGCTGTGGGTCCAGAAAGTTGAATACAAACTGAGTTAGTCCACTTTACAGGGTGTGACTCCCAG
CCTCATGTTCCCACATGTCAATACCAGGTCTCTTCCCGGAGTTGGCACACTGCAGAGTCCCTGG
GTCTTTTGTGTTGAGGCGAAGGTCTGCAGCCCAGCAGGGAGTTCAGCTGGACAAATACGTGGCC
CTTTTGCCTACAGATGCGGTTCCGTTTTGGTGACGTGTTCAGCCTGCAGCTGGCCTGGAAGCCT
GTCATTGTGCTCAATGGGCTGGCCGCTGTGCGGGAGGCGCTGGTGAACCACAATGAGTACACCT
CCGACCGCCCGTGGATGCCCATCTATGAGCACCTGGGCTTCGGACCACGGTCTCAAGGTGTGAT
CATGGCAACCTATGGACATGCCTGGCGTGAGCAGCGGCGCTTCTCTGTGTCCACCATGCGCAAC
TTTGGCCTGGGCAAGAAGTCCCTGGAGCAGTGGGTGACCAAGGAGGCCAGCTGCCTCTGTACAG
CCTTTGCCAACAAGGCTGGAAGCCCCTTTAACCCCATGTCCCTGCTGAAGAGAGCAGTGTGCAA
CGTGATCTCCTCCCTCATCTATGCCCGACGCTTTGAGTATGATGAACAGCGCTTGGCCAAGATT
CTTGACCTTCTGGAGGACACAGTGAAGGAGGATTCCGGCTTTATGCCCATGGTGCTGAATGTGG
TCCCAGTGCTCCTGCGCATCCCCGGGCTGCCTGGCAGGGTCTTCCCTGCACAGAAGGCCTTCAT
GGCCATGGTGGATGAGCTGTTGGAGGAGCACAGGATGACCTGGGACCCAGCCCAGCCACCGCGA
GACCTGACTGACGCCTTCCTGGCGGAGGTGGAGAAGGCCAAGGGGAACCCTGAGAGCAGCTTCA
ATGATGAGAACCTGCGCATCATGGTGCTTGATCTGTTCACCGCGGGGATGGTGACCACTTCGAC
CACGCTGGCCTGGGCCCTCCTGCTCATGATCCTGCACCCGGATGTGCAGCGCCGTGTCCAACAG
GAGATTGATGAAGTGATAGGGCAGGTGCGGCAGCCAGAGATGGGGGACCAGGACCGCATGCCCT
TCACCATGGCTGTGATTCACGAGGTGCAGCGTTTTGGAGACCTTGTCCCTCTAGGTCTACCCCA
CTCAACAACCCGTGACATTGAGTTGCAGGGCTTCTTCATCCCCAAGGGGACGATGCTCATCACC
AACCTGTCGTCTGTGCTGAAGGATGAGACCGTCTGGGAGAAGCCCCTCCACTTTCACCCTGGAC
ACTTCCTGGATGCCCAGGGCCACTTTGTGAAGCGGGAGGCCTTCATGCCTTTCTCAGCAGGCCG
CCGTGTGTGCCTCGGGGAGCCCCTGGCCCGCATGGAGCTCTTCCTCTTCTTCACCTGCCTCCTG
CAGCGCTTTAGCTTCTCGGTGCCCCCTGGACAAGCCCAGCCCAGCGACTATGGCGTGTTTGGTA
CCATAGTGACCCCGTCCCCCTACCAACTGTGTGCTAAGTCCCGCTAGAGGAGGTGCAGACCCCA
ACCCTGCCTCCAGACGGGGCTCTGATGTTCAATAAACCAGTCTTGTCACTGCCACTTTATTCTG
A

hide sequence

RefSeq Acc Id:

XM_021735451 ⟹ XP_021591126

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,804,025 - 6,827,523 (+)	NCBI
SpeTri2.0	NW_004936718	153,340 - 157,966 (-)	NCBI

Sequence:

show sequence

GGATTAATCCCCAGTACCCTCCGACACCCAGGGTCAGGGAGAGTCTGGTGGATCACAGTGGAGG
GAACCCAGGACGAAGAGAGATGGGTGGAGGGTGAAGCCAAGGTGGACCAGTAGTTGTGCAGTGA
AAGGAAGCAGGCTGAGAGGTGTCCTGGTTGATGGCACGGCAGACAGAGCCCGAGGACCCTTTCA
ACTTTCCAAGGGCAAAGGTGTGAGAGGACAAAGGCCAGGAGGTGGGACTGGACTTGGCAGTGGG
TTTGGGATCCAGGTGGGCAGGTATAAATTGAATAGGCCCCAGTCCCTTGTGATTCCATCAGAGG
GAAAGGTCTTGGGGATGGGGGAGGAGCCATAAGAGCTTGTCAGTCAGGAACTGAAGGTGGACAC
AGATTGACAGACCCACTTAAAATTTTCTGCTGTGGGTCTTGCGCCTCACTGCTCACCTGTGTGA
CCGTGTCTTCTGCTCTGTACAGTGGAGCACTATTGTCCCCATTGACGATATCCTGATTGGCAAG
GTCATAGCTGTGGGTCCAGAAAGTTGAATACAAACTGAGTTAGTCCACTTTACAGGGTGTGACT
CCCAGCCTCATGTTCCCACATGTCAATACCAGGTCTCTTCCCGGAGTTGGCACACTGCAGAGTC
CCTGGGTCTTTTGTGTTGAGGCGAAGGTCTGCAGCCCAGCAGGGAGTTCAGCTGGACAAATACG
TGGCCCTTTTGCCTACAGATGCGGTTCCGTTTTGGTGACGTGTTCAGCCTGCAGCTGGCCTGGA
AGCCTGTCATTGTGCTCAATGGGCTGGCCGCTGTGCGGGAGGCGCTGGTGAACCACAATGAGTA
CACCTCCGACCGCCCGTGGATGCCCATCTATGAGCACCTGGGCTTCGGACCACGGTCTCAAGGT
GTGATCATGGCAACCTATGGACATGCCTGGCGTGAGCAGCGGCGCTTCTCTGTGTCCACCATGC
GCAACTTTGGCCTGGGCAAGAAGTCCCTGGAGCAGTGGGTGACCAAGGAGGCCAGCTGCCTCTG
TACAGCCTTTGCCAACAAGGCTGGAAGCCCCTTTAACCCCATGTCCCTGCTGAAGAGAGCAGTG
TGCAACGTGATCTCCTCCCTCATCTATGCCCGACGCTTTGAGTATGATGAACAGCGCTTGGCCA
AGATTCTTGACCTTCTGGAGGACACAGTGAAGGAGGATTCCGGCTTTATGCCCATGGTGCTGAA
TGTGGTCCCAGTGCTCCTGCGCATCCCCGGGCTGCCTGGCAGGGTCTTCCCTGCACAGAAGGCC
TTCATGGCCATGGTGGATGAGCTGTTGGAGGAGCACAGGATGACCTGGGACCCAGCCCAGCCAC
CGCGAGACCTGACTGACGCCTTCCTGGCGGAGGTGGAGAAGGCCAAGGGGAACCCTGAGAGCAG
CTTCAATGATGAGAACCTGCGCATCATGGTGCTTGATCTGTTCACCGCGGGGATGGTGACCACT
TCGACCACGCTGGCCTGGGCCCTCCTGCTCATGATCCTGCACCCGGATGTGCAGCGCCGTGTCC
AACAGGAGATTGATGAAGTGATAGGGCAGGTGCGGCAGCCAGAGATGGGGGACCAGGACCGCAT
GCCCTTCACCATGGCTGTGATTCACGAGGTGCAGCGTTTTGGAGACCTTGTCCCTCTAGGTCTA
CCCCACTCAACAACCCGTGACATTGAGTTGCAGGGCTTCTTCATCCCCAAGGGGACGACGCTCA
TCACCAACCTGTCGTCTGTGCTGAAGGATGAGACCGTCTGGGAGAAGCCCCTCCACTTTCACCC
TGGACACTTCCTGGATGCCCAGGGCCACTTTGTGAAGCGGGAGGCCTTCATGCCTTTCTCAGCA
GGCCGCCGTGTGTGTCTCGGGGAGCCCCTGGCCCGCATGGAGCTCTTCCTCTTCTTCACCTGCC
TCCTGCAGCGCTTTAGCTTCTCGGTGCCCCCTGGACAAGCCCAGCCCAGCGACTATGGCGTGTT
TGGTACCATAGTGACCCCGTCCCCCTACCAACTGTGTGCTAAGTCCCGCTAGAGGAGGTGCAGA
CCCCAACCCTGCCTCCAGACGGGGCTCTGATGTTCAATAAACCAGTCTTGTCACTGCCACTTTA
TTCTGA

hide sequence

RefSeq Acc Id:

XM_040277137 ⟹ XP_040133071

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,822,112 - 6,829,968 (+)	NCBI

RefSeq Acc Id:

XM_040277141 ⟹ XP_040133075

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,822,112 - 6,829,968 (+)	NCBI

RefSeq Acc Id:

XM_040277146 ⟹ XP_040133080

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,822,112 - 6,829,968 (+)	NCBI

RefSeq Acc Id:

XM_040277149 ⟹ XP_040133083

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,822,112 - 6,829,968 (+)	NCBI

RefSeq Acc Id:

XM_040277156 ⟹ XP_040133090

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,822,111 - 6,829,968 (+)	NCBI

RefSeq Acc Id:

XM_040277158 ⟹ XP_040133092

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,822,110 - 6,843,868 (+)	NCBI

RefSeq Acc Id:

XM_040277163 ⟹ XP_040133097

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,822,110 - 6,843,868 (+)	NCBI

RefSeq Acc Id:

XM_040277167 ⟹ XP_040133101

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,822,110 - 6,843,861 (+)	NCBI

RefSeq Acc Id:

XM_040277174 ⟹ XP_040133108

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,822,110 - 6,843,861 (+)	NCBI

RefSeq Acc Id:

XM_040277178 ⟹ XP_040133112

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,822,110 - 6,826,326 (+)	NCBI

RefSeq Acc Id:

XM_040277182 ⟹ XP_040133116

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,822,110 - 6,826,326 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_021591124	(Get FASTA)	NCBI Sequence Viewer
	XP_021591126	(Get FASTA)	NCBI Sequence Viewer
	XP_040133071	(Get FASTA)	NCBI Sequence Viewer
	XP_040133075	(Get FASTA)	NCBI Sequence Viewer
	XP_040133080	(Get FASTA)	NCBI Sequence Viewer
	XP_040133083	(Get FASTA)	NCBI Sequence Viewer
	XP_040133090	(Get FASTA)	NCBI Sequence Viewer
	XP_040133092	(Get FASTA)	NCBI Sequence Viewer
	XP_040133097	(Get FASTA)	NCBI Sequence Viewer
	XP_040133101	(Get FASTA)	NCBI Sequence Viewer
	XP_040133108	(Get FASTA)	NCBI Sequence Viewer
	XP_040133112	(Get FASTA)	NCBI Sequence Viewer
	XP_040133116	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000020940.2
	ENSSTOP00000024863.1
	ENSSTOP00000025902.1
GenBank Protein	KAG3290807	(Get FASTA)	NCBI Sequence Viewer
	KAG3290808	(Get FASTA)	NCBI Sequence Viewer
	KAG3290809	(Get FASTA)	NCBI Sequence Viewer
	KAG3290810	(Get FASTA)	NCBI Sequence Viewer
	KAG3290811	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_021591126 ⟸ XM_021735451
- Peptide Label:	isoform X13
- UniProtKB:	A0A287CX73 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRFRFGDVFSLQLAWKPVIVLNGLAAVREALVNHNEYTSDRPWMPIYEHLGFGPRSQGVIMATY GHAWREQRRFSVSTMRNFGLGKKSLEQWVTKEASCLCTAFANKAGSPFNPMSLLKRAVCNVISS LIYARRFEYDEQRLAKILDLLEDTVKEDSGFMPMVLNVVPVLLRIPGLPGRVFPAQKAFMAMVD ELLEEHRMTWDPAQPPRDLTDAFLAEVEKAKGNPESSFNDENLRIMVLDLFTAGMVTTSTTLAW ALLLMILHPDVQRRVQQEIDEVIGQVRQPEMGDQDRMPFTMAVIHEVQRFGDLVPLGLPHSTTR DIELQGFFIPKGTTLITNLSSVLKDETVWEKPLHFHPGHFLDAQGHFVKREAFMPFSAGRRVCL GEPLARMELFLFFTCLLQRFSFSVPPGQAQPSDYGVFGTIVTPSPYQLCAKSR hide sequence

RefSeq Acc Id:	XP_021591124 ⟸ XM_021735449
- Peptide Label:	isoform X1
- UniProtKB:	A0A287CX73 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRFRFGDVFSLQLAWKPVIVLNGLAAVREALVNHNEYTSDRPWMPIYEHLGFGPRSQGVIMATY GHAWREQRRFSVSTMRNFGLGKKSLEQWVTKEASCLCTAFANKAGSPFNPMSLLKRAVCNVISS LIYARRFEYDEQRLAKILDLLEDTVKEDSGFMPMVLNVVPVLLRIPGLPGRVFPAQKAFMAMVD ELLEEHRMTWDPAQPPRDLTDAFLAEVEKAKGNPESSFNDENLRIMVLDLFTAGMVTTSTTLAW ALLLMILHPDVQRRVQQEIDEVIGQVRQPEMGDQDRMPFTMAVIHEVQRFGDLVPLGLPHSTTR DIELQGFFIPKGTMLITNLSSVLKDETVWEKPLHFHPGHFLDAQGHFVKREAFMPFSAGRRVCL GEPLARMELFLFFTCLLQRFSFSVPPGQAQPSDYGVFGTIVTPSPYQLCAKSR hide sequence

RefSeq Acc Id:	XP_040133092 ⟸ XM_040277158
- Peptide Label:	isoform X7
- UniProtKB:	I3N994 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040133097 ⟸ XM_040277163
- Peptide Label:	isoform X8
- UniProtKB:	I3N994 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040133101 ⟸ XM_040277167
- Peptide Label:	isoform X9
- UniProtKB:	I3N994 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040133108 ⟸ XM_040277174
- Peptide Label:	isoform X10
- UniProtKB:	I3N994 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040133112 ⟸ XM_040277178
- Peptide Label:	isoform X11

RefSeq Acc Id:	XP_040133116 ⟸ XM_040277182
- Peptide Label:	isoform X12

RefSeq Acc Id:	XP_040133090 ⟸ XM_040277156
- Peptide Label:	isoform X6
- UniProtKB:	A0A287CUB7 (UniProtKB/TrEMBL), A0A287CX73 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040133071 ⟸ XM_040277137
- Peptide Label:	isoform X2
- UniProtKB:	A0A287CX73 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040133075 ⟸ XM_040277141
- Peptide Label:	isoform X3
- UniProtKB:	A0A287CX73 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040133080 ⟸ XM_040277146
- Peptide Label:	isoform X4
- UniProtKB:	A0A287CX73 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040133083 ⟸ XM_040277149
- Peptide Label:	isoform X5
- UniProtKB:	A0A287CUB7 (UniProtKB/TrEMBL), A0A287CX73 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000020124	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000029369.2	UniProtKB/TrEMBL
	ENSSTOT00000033067.1	UniProtKB/TrEMBL
	ENSSTOT00000038346.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.630.10	UniProtKB/TrEMBL
InterPro	Cyt_P450	UniProtKB/TrEMBL
	Cyt_P450_CS	UniProtKB/TrEMBL
	Cyt_P450_E_grp-I	UniProtKB/TrEMBL
	Cyt_P450_E_grp-I_CYP2D-like	UniProtKB/TrEMBL
	Cyt_P450_sf	UniProtKB/TrEMBL
NCBI Gene	LOC101961588	ENTREZGENE
PANTHER	CYTOCHROME P450 2D6-RELATED	UniProtKB/TrEMBL
	CYTOCHROME P450 508A4-RELATED	UniProtKB/TrEMBL
Pfam	p450	UniProtKB/TrEMBL
PRINTS	EP450I	UniProtKB/TrEMBL
	EP450ICYP2D	UniProtKB/TrEMBL
	P450	UniProtKB/TrEMBL
PROSITE	CYTOCHROME_P450	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48264	UniProtKB/TrEMBL
UniProt	A0A287CUB7	ENTREZGENE, UniProtKB/TrEMBL
	A0A287CX73	ENTREZGENE, UniProtKB/TrEMBL
	I3N994	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-26	LOC101961588	cytochrome P450 2D17	LOC101961588	cytochrome P450 2D4-like	Symbol and/or name change	5135510	APPROVED
2021-03-25	LOC101961588	cytochrome P450 2D4-like	LOC110599497	uncharacterized LOC110599497	Data merged from RGD:13020762	737654	PROVISIONAL
2021-03-25	LOC101961588	cytochrome P450 2D4-like	LOC106145311	uncharacterized LOC106145311	Data merged from RGD:12673144	737654	PROVISIONAL
2017-07-13	LOC101961588	cytochrome P450 2D4-like		cytochrome P450 2D17-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB